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Ring-rearrangement metathesis of bicyclic amino acid derivatives

Maechling, S., Norman, S.E., McKendrick, J.E., Basra, S., Koppner, K. and Blechert, S. (2006) Ring-rearrangement metathesis of bicyclic amino acid derivatives. Tetrahedron Letters, 47 (2). pp. 189-192. ISSN 0040-4039

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To link to this article DOI: 10.1016/j.tetlet.2005.10.155

Abstract/Summary

In this letter, we describe the ring-rearrangement metathesis (RRM) of bicyclic amino acid derivatives. The procedure is of use for the synthesis of constrained amino acid and peptide derivatives with potential as reverse-turn inducers. (c) 2005 Elsevier Ltd. All rights reserved.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:11448
Uncontrolled Keywords:metathesis, amino acids, peptides, peptidomimetics, REGIOSELECTIVE DOMINO METATHESIS, CLOSING OLEFIN METATHESIS, DIELS-ALDER REACTION, EFFICIENT SYNTHESIS, CONFORMATIONAL-ANALYSIS, ASYMMETRIC-SYNTHESIS, FREIDINGER LACTAMS, PEPTIDES, PEPTIDOMIMETICS, CATALYSTS

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