Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reactionTools  Marrero, J.G. and Harwood, L.M. (2009) Towards the total synthesis of colletofragarones: constructing the macrocyclic lactone by high pressure-mediated intramolecular Diels-Alder reaction. Tetrahedron Letters, 50 (26). pp. 3574-3576. ISSN 0040-4039 Full text not archived in this repository. To link to this article DOI: 10.1016/j.tetlet.2009.03.063 Abstract/SummaryWe report herein an intramolecular Diels-Alder approach towards the construction of the macrocyclic lactone ring and the perhydrobenzofuran system of the colletofragarones, novel metabolites produced by fungi of the genus Colletotrichum that are responsible for inhibition of germination of the conidia in these species. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.
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