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A homo-proline tetrazole as an improved organocatalyst for the asymmetric Michael addition of carbonyl compounds to nitro-olefins

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Mitchell, C.E.T., Cobb, A.J.A. and Ley, S.V. (2005) A homo-proline tetrazole as an improved organocatalyst for the asymmetric Michael addition of carbonyl compounds to nitro-olefins. Synlett (4). pp. 611-614. ISSN 0936-5214

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To link to this article DOI: 10.1055/s-2005-862392

Abstract/Summary

A new homo-proline tetrazole derivative 7 has been prepared and shown to have improved properties for achieving asymmetric Michael addition of carbonyl compounds to nitro-olefins.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy
ID Code:13687
Uncontrolled Keywords:asymmetric, nitro-Michael, organocatalysis, homoproline, tetrazole , MANNICH-TYPE REACTIONS, AMINO-ACID DERIVATIVES, ALPHA-AMINO, ONE-POT, ALDEHYDE DONORS, ALDOL REACTIONS, KETONES, 5-PYRROLIDIN-2-YLTETRAZOLE, NITROOLEFINS, NITROSTYRENE
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