Regression, developmental trajectory and associated problems in disorders in the autism spectrum: the SNAP study
Baird, G., Charman, T., Pickles, A., Chandler, S., Loucas, T., Meldrum, D., Carcani-Rathwell, I., Serkana, D. and Simonoff, E. (2008) Regression, developmental trajectory and associated problems in disorders in the autism spectrum: the SNAP study. Journal of Autism and Developmental Disorders, 38 (10). pp. 1827-1836. ISSN 0162-3257
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To link to this article DOI: 10.1007/s10803-008-0571-9
We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with non-ASD neurodevelopmental problems, drawn from those with special educational needs within a population of 56,946 children. Language regression was reported in 30% with narrowly defined autism, 8% with broader ASD and less than 3% with developmental problems without ASD. A smaller group of children were identified who underwent a less clear setback. Regression was associated with higher rates of autistic symptoms and a deviation in developmental trajectory. Regression was not associated with epilepsy or gastrointestinal problems.