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Theoretical insights into bacterial chemotaxis

Tindall, M., Gaffney, E. A., Maini, P. K. and Armitage, J. P. (2012) Theoretical insights into bacterial chemotaxis. Wiley interdisciplinary reviews. Systems biology and medicine, 4 (3). pp. 247-259. ISSN 1939-005X

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To link to this article DOI: 10.1002/wsbm.1168

Abstract/Summary

Research into understanding bacterial chemotactic systems has become a paradigm for Systems Biology. Experimental and theoretical researchers have worked hand-in-hand for over 40 years to understand the intricate behavior driving bacterial species, in particular how such small creatures, usually not more than 5 µm in length, detect and respond to small changes in their extracellular environment. In this review we highlight the importance that theoretical modeling has played in providing new insight and understanding into bacterial chemotaxis. We begin with an overview of the bacterial chemotaxis sensory response, before reviewing the role of theoretical modeling in understanding elements of the system on the single cell scale and features underpinning multiscale extensions to population models. WIREs Syst Biol Med 2012 doi: 10.1002/wsbm.1168 For further resources related to this article, please visit the WIREs website.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
Faculty of Life Sciences > School of Biological Sciences > Biomedical Sciences
Faculty of Science > School of Mathematical and Physical Sciences > Department of Mathematics and Statistics
ID Code:27987
Publisher:Wiley

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