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Application of hydrogen-bond propensity calculations to an indomethacin–nicotinamide (1:1) co-crystal

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Majumder, M., Buckton, G., Rawlinson, C. F., Williams, A. C. ORCID: https://orcid.org/0000-0003-3654-7916, Spillman, M. J., Pidcok, E. and Shankland, K. (2013) Application of hydrogen-bond propensity calculations to an indomethacin–nicotinamide (1:1) co-crystal. CrystEngComm, 15. pp. 4041-4044. ISSN 1466-8033

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To link to this item DOI: 10.1039/c3ce40367j

Abstract/Summary

The crystal structure of an indomethacin–nicotinamide (1 : 1) cocrystal produced by milling has been determined from laboratory powder X-ray diffraction (PXRD) data. The hydrogen bonding motifs observed in the structure represent one of the most probable of all the possible combinations of donors and acceptors in the constituent molecules.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group
ID Code:32474
Publisher:Royal Society of Chemistry
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