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Investigation of Petasis and Ugi reactions in series in an automated microreactor system

Heublein, N., Moore, J. S., Smith, C. D. and Jensen, K. F. (2014) Investigation of Petasis and Ugi reactions in series in an automated microreactor system. RSC Advances, 4. pp. 363627-63631. ISSN 2046-2069

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To link to this item DOI: 10.1039/c4ra13626h

Abstract/Summary

Petasis and Ugi reactions are used successively without intermediate purification, effectively accomplishing a six-component reaction. The examined reactions are transferred from traditional batch reactors to an automated continuous flow microreactor setup, where optimization and kinetic analyses are performed, proposed mechanisms evaluated, and rate-limiting steps determined.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Chemical Analysis Facility (CAF)
Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:39086
Publisher:Royal Society of Chemistry

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