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Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing

Cook, M. T., Smith, S. L. and Khutoryanskiy, V. V. (2015) Novel glycopolymer hydrogels as mucosa-mimetic materials to reduce animal testing. Chemical Communications, 51 (77). pp. 14447-14450. ISSN 1359-7345

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To link to this item DOI: 10.1039/C5CC02428E

Abstract/Summary

Glycopolymer hydrogels capable of mimicking mucosal tissue in mucoadhesion testing have been designed. Liquid formulations containing mucoadhesive polymers were found to be retained on these tissues to the same extent as ex vivo gastric mucosa, when using a dynamic method of assessing mucoadhesion.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Chemical Analysis Facility (CAF)
Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > NMR (CAF)
Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Electron Microscopy Laboratory (CAF)
Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group
ID Code:42544
Publisher:The Royal Society of Chemistry

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