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Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

Hamley, I. W., Kirkham, S., Kowalczyk, R. M., Castelletto, V., Reza, M. and Ruokolainen, J. (2015) Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes. Chemical Communications, 51 (100). pp. 17680-17683. ISSN 1359-7345

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To link to this item DOI: 10.1039/C5CC08224B

Abstract/Summary

The amphiphilic polyene amphotericin B, a powerful treatment for systemic fungal infections, is shown to exhibit a critical aggregation concentration, and to form giant helically-twisted nanostructures via self-assembly in basic aqueous solution.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:48786
Publisher:The Royal Society of Chemistry

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