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Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles

Neuman, B. W. (2016) Bioinformatics and functional analyses of coronavirus nonstructural proteins involved in the formation of replicative organelles. Antiviral Research, 135. pp. 97-107. ISSN 0166-3542

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To link to this item DOI: 10.1016/j.antiviral.2016.10.005

Abstract/Summary

Replication of eukaryotic positive-stranded RNA viruses is usually linked to the presence of membrane-associated replicative organelles. The purpose of this review is to discuss the function of proteins responsible for formation of the coronavirus replicative organelle. This will be done by identifying domains that are conserved across the order Nidovirales, and by summarizing what is known about function and structure at the level of protein domains.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Biological Sciences > Biomedical Sciences
ID Code:67978
Publisher:Elsevier

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