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Combining C-H functionalisation and flow photochemical heterocyclic metamorphosis (FP-HM) for the synthesis of benzo[1,3]oxazepines

Babra, J. S., Russell, A. T., Smith, C. D. and Zhang, Y. (2018) Combining C-H functionalisation and flow photochemical heterocyclic metamorphosis (FP-HM) for the synthesis of benzo[1,3]oxazepines. Tetrahedron, 74 (38). pp. 5351-5357. ISSN 0040-4020

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To link to this item DOI: 10.1016/j.tet.2018.05.066

Abstract/Summary

C-H Activation/functionalisation and Flow Photochemical Heterocyclic Metamorphosis (FP-HM) have been combined to synthesize a library of benzo[1,3]oxazepines, a rarely described heterocyclic family. This combined protocol allows a range of arylated products to be made from simple starting materials, and the cheap flow photochemical system has proven effective for rapid synthesis of gram-quantities of benzo[1,3]oxazepines.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Chemical Analysis Facility (CAF)
Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Mass Spectrometry (CAF)
Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > NMR (CAF)
ID Code:77396
Uncontrolled Keywords:Flow; Photochemistry; Heterocyclic metamorphosis; Quinoline N-oxide; Benzo[1,3]oxazepine
Publisher:Elsevier

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