Accessibility navigation

Self-immolative systems for the disclosure of reactive electrophilic alkylating agents

Lists
Tools

Acton, A. L., Leroux, F., Feula, A., Melia, K., Sambrook, M. R., Hayes, W. ORCID: https://orcid.org/0000-0003-0047-2991 and Russell, A. T. (2019) Self-immolative systems for the disclosure of reactive electrophilic alkylating agents. Chemical Communications, 55. pp. 5219-5222. ISSN 1359-7345

[img]
Preview
 Text (Open access) - Published Version
· Available under License Creative Commons Attribution.
· Please see our End User Agreement before downloading.
3MB
[img] Text - Accepted Version
· Restricted to Repository staff only
1MB

It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1039/C8CC09728C

Abstract/Summary

In this paper we report the design, synthesis and assessment of the first examples of self-immolative systems triggered by non-acidic electrophilic agents such as methyl, allyl or benzylic halides. These systems provide a visual colorimetric disclosure response upon exposure to these electrophilic reagents under mild, basic conditions without the need for the use of analytical instrumentation.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Chemical Analysis Facility (CAF)
Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:82743
Publisher:The Royal Society of Chemistry
Download Statistics

Downloads

Downloads per month over past year

Altmetric
Deposit Details

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation

See also