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Self-immolative systems for the disclosure of reactive electrophilic alkylating agents

Acton, A. L., Leroux, F., Feula, A., Melia, K., Sambrook, M. R., Hayes, W. and Russell, A. T. (2019) Self-immolative systems for the disclosure of reactive electrophilic alkylating agents. Chemical Communications, 55. pp. 5219-5222. ISSN 1359-7345

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To link to this item DOI: 10.1039/C8CC09728C

Abstract/Summary

In this paper we report the design, synthesis and assessment of the first examples of self-immolative systems triggered by non-acidic electrophilic agents such as methyl, allyl or benzylic halides. These systems provide a visual colorimetric disclosure response upon exposure to these electrophilic reagents under mild, basic conditions without the need for the use of analytical instrumentation.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Chemical Analysis Facility (CAF)
Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:82743
Publisher:The Royal Society of Chemistry

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