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Formation of triple helical nanofibers using self-assembling chiral benzene-1,3,5-tricarboxamides and reversal of the nanostructure's handedness using mirror image building blocks

Bose, P.P., Drew, M.G.B., Das, A.K. and Banerjee, A. (2006) Formation of triple helical nanofibers using self-assembling chiral benzene-1,3,5-tricarboxamides and reversal of the nanostructure's handedness using mirror image building blocks. Chemical Communications (30). pp. 3196-3198. ISSN 1359-7345

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To link to this item DOI: 10.1039/b606371c

Abstract/Summary

Intertwining triple helical nanofibers with an overall handedness have been formed from self-assembling chiral benzene-1,3,5-tricarboxamides 1, 2 and 3, whereas the achiralbenzene-1,3,5-tricarboxamide 4 upon self-association gives rise to straight nanofibers without any twist and transmission electron microscopy images of chiral compounds clearly demonstrate that the handedness of the triple helical nanofibers can be reversed by using the enantiomeric benzene-1,3,5-tricarboxamide building blocks.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:11045
Uncontrolled Keywords:PEPTIDE-AMPHIPHILE NANOFIBERS, BETA-SHEET STRUCTURE, SUPRAMOLECULAR, CHIRALITY, DESIGNED PEPTIDE, PROTEIN, FIBER, SCAFFOLD, CELLS, NANOPARTICLES, FABRICATION

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