Download
Download![[thumbnail of WRglassRevisedNoTrackb.pdf]](https://centaur.reading.ac.uk/style/images/fileicons/text.png "WRglassRevisedNoTrackb.pdf")
Castelletto, V. 
ORCID: https://orcid.org/0000-0002-3705-0162 and Hamley, I. W. ORCID: https://orcid.org/0000-0002-4549-0926
(2026)
Chiral glass formation by Dipeptide salts.
Biomacromolecules.
ISSN 1525-7797
doi: 10.1021/acs.biomac.5c02634
Abstract/Summary
A simple dipeptide WR (tryptophan–arginine) in the form of salts with organic acids tartaric acid or crotonic acid is shown to form glasses through a benign preparation route by evaporation of aqueous solution. The glasses have a remarkable range of properties including moldability, high transparency across a broad range of wavelengths, and fluorescence. The glasses show self-healing and adhesive properties, and have accessible glass transition temperatures. The glasses are shown to be amorphous via small-angle and wide-angle X-ray scattering (SAXS/WAXS) and scanning electron microscopy (SEM). Remarkably, the glasses are found to have a chiral structure, as shown by circular dichroism (CD) spectroscopy. Investigation of glass precursor dipeptide salt solutions shows that the glasses form from an initial unordered solution containing chiral peptide molecules. The diverse properties of the dipeptide glass materials points to a wide range of potential future applications.
Altmetric Badge
Dimensions Badge
| Item Type | Article |
| URI | https://centaur.reading.ac.uk/id/eprint/128503 |
| Identification Number/DOI | 10.1021/acs.biomac.5c02634 |
| Refereed | Yes |
| Divisions | Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Optical Spectroscopy (CAF) Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Thermal Analysis (CAF) Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Xray (CAF) Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Electron Microscopy Laboratory (CAF) |
| Publisher | American Chemical Society |
| Download/View statistics | View download statistics for this item |
Downloads
Downloads per month over past year
University Staff: Request a correction | Centaur Editors: Update this record