Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis

Friede, T.; Parsons, N.; Stallard, N.; Todd, Susan; Valdes Marquez, E.; Chataway, J.; Nicholas, R.

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Friede, T., Parsons, N., Stallard, N., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Valdes Marquez, E., Chataway, J. and Nicholas, R. (2011) Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis. Statistics in Medicine, 30 (13). pp. 1528-1540. ISSN 1097-0258 doi: 10.1002/sim.4202

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Item Type	Article
URI	https://centaur.reading.ac.uk/id/eprint/23387
Identification Number/DOI	10.1002/sim.4202
Refereed	Yes
Divisions	Science > School of Mathematical, Physical and Computational Sciences > Department of Mathematics and Statistics > Applied Statistics Science > School of Mathematical, Physical and Computational Sciences > Department of Mathematics and Statistics
Uncontrolled Keywords	adaptive seamless design; closed test procedure; combination test; short-term endpoint; surrogate endpoint
Publisher	Wiley
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