Number of items: 88.
Article
Flight, L., Julious, S., Brennan, A. and Todd, S.
ORCID: https://orcid.org/0000-0002-9981-923X
(2022)
Expected value of sample information to guide the design of group sequential clinical trials.
Medical Decision Making, 42 (4).
pp. 461-473.
ISSN 1552-681X
doi: https://doi.org/10.1177/0272989X211045036
Markey, O., Vasilopoulou, D., Kliem, K. E., Fagan, C. C., Grandison, A. S., Sutton, R., Humphries, D. J., Todd, S.
ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G.
ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. and Lovegrove, J. A.
(2022)
Effect of fat reformulated dairy food consumption on postprandial flow-mediated dilatation and cardiometabolic risk biomarkers compared with conventional dairy: a randomized, controlled trial.
American Journal of Clinical Nutrition, 115 (3).
pp. 679-693.
ISSN 0002-9165
doi: https://doi.org/10.1093/ajcn/nqab428
Markey, O., Vasilopoulou, D., Kliem, K. E., Fagan, C. C., Grandison, A. S., Sutton, R., Humphries, D. J., Todd, S.
ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G.
ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. and Lovegrove, J. A.
(2021)
Postprandial fatty acid profile, but not cardiometabolic risk markers, is modulated by dairy fat manipulation in adults with moderate cardiovascular disease risk: the randomized controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) study.
Journal of Nutrition, 151 (7).
pp. 1755-1768.
ISSN 1541-6100
doi: https://doi.org/10.1093/jn/nxab050
Emmerson, J., Todd, S.
ORCID: https://orcid.org/0000-0002-9981-923X and Brown, J. M.
(2021)
Recommendations for designing and analysing multi-arm non-inferiority trials: a review of methodology and current practice.
Trials, 22 (1).
417.
ISSN 1745-6215
doi: https://doi.org/10.1186/s13063-021-05364-9
Dimier, N. and Todd, S.
ORCID: https://orcid.org/0000-0002-9981-923X
(2021)
Assessment of the information theory approach to
evaluating time-to-event surrogate and true endpoints in a
meta-analytic setting.
Pharmaceutical Statistics, 20 (2).
pp. 335-347.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.2080
Howard, D. R., Hockaday, A., Brown, J. M., Gregory, W. M., Todd, S.
ORCID: https://orcid.org/0000-0002-9981-923X, Munir, T., Oughton, J. B., Dimbleby, C. and Hillmen, P.
(2021)
A platform trial in practice: adding a new experimental research arm to the ongoing confirmatory FLAIR trial in chronic lymphocytic leukaemia.
Trials, 22 (1).
38.
ISSN 1745-6215
doi: https://doi.org/10.1186/s13063-020-04971-2
Kimani, P. K., Todd, S., Renfro, L. A., Glimm, E., Khan, J. N., Kairalla, J. A. and Stallard, N.
(2020)
Point and interval estimation in two-stage adaptive designs with time to event data and biomarker-driven subpopulation selection.
Statistics in Medicine, 39 (19).
pp. 2568-2586.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.8557
Dimairo, M., Pallmann, P., Wason, J., Todd, S., Jaki, T., Julious, S., Mander, A., Weir, C., Koenig, F., Walton, M., Nicholl, J., Coates, E., Biggs, K., Hamasaki, T., Proschan, M., Scott, J., Ando, Y., Hind, D. and Altman, D.
(2020)
The adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an adaptive design.
British Medical Journal, 369.
m115.
ISSN 1468-5833
doi: https://doi.org/10.1136/bmj.m115
Vasilopoulou, D., Markey, O., Kliem, K. E., Fagan, C. C., Grandison, A. S., Humphries, D. J., Todd, S.
ORCID: https://orcid.org/0000-0002-9981-923X, Jackson, K. G.
ORCID: https://orcid.org/0000-0002-0070-3203, Givens, D. I. and Lovegrove, J. A.
(2020)
Reformulation initiative for partial replacement of saturated with unsaturated fats in dairy foods attenuates the increase in LDL cholesterol and improves flow-mediated dilatation compared with conventional dairy: the randomized, controlled REplacement of SaturatEd fat in dairy on Total cholesterol (RESET) study.
The American Journal of Clinical Nutrition, 111 (4).
pp. 739-748.
ISSN 1938-3207
doi: https://doi.org/10.1093/ajcn/nqz344
Flight, L., Julious, S., Brennan, A., Todd, S. T. and Hind, D.
(2020)
How can health economics be used in the design and analysis of adaptive clinical trials? A qualitative analysis.
Trials, 21.
252.
ISSN 1745-6215
doi: https://doi.org/10.1186/s13063-020-4137-2
Stallard, N., Todd, S., Ryan, E. G. and Gates, S.
(2020)
Comparison of Bayesian and frequentist
group-sequential clinical trial designs.
BMC Medical Research Methodology, 20 (1).
ISSN 1471-2288
doi: https://doi.org/10.1186/s12874-019-0892-8
Stallard, N., Todd, S., Parashar, D., Kimani, P. K. and Renfro, L. A.
(2019)
On the need to adjust for multiplicity in confirmatory clinical trials with master protocols.
Annals of Oncology, 30 (4).
pp. 506-509.
ISSN 1569-8041
doi: https://doi.org/10.1093/annonc/mdz038
Kliem, K. E., Humphries, D. J., Markey, O., Vasilopoulou, D., Fagan, C. C., Grandison, A. S., Jackson, K. G., Todd, S., Givens, I. D. and Lovegrove, J. A.
(2019)
Food chain approach to lowering the saturated fat of milk and dairy products.
International Journal of Dairy Technology, 72 (1).
pp. 100-109.
ISSN 1364-727X
doi: https://doi.org/10.1111/1471-0307.12564
Abery, J. E. and Todd, S.
(2019)
Comparing the MAMS framework with the combination method in multi-arm adaptive trials with binary outcomes.
Statistical Methods in Medical Research, 28 (6).
pp. 1716-1730.
ISSN 0962-2802
doi: https://doi.org/10.1177/0962280218773546
Flight, L., Arshad, F., Barnsley, R., Patel, K., Julious, S., Brennan, A. and Todd, S.
(2019)
A review of clinical trials with an adaptive design and health economic analysis.
Value in Health, 22 (4).
pp. 391-398.
ISSN 1098-3015
doi: https://doi.org/10.1016/j.jval.2018.11.008
Dimairo, M., Coates, E., Pallmann, P., Todd, S., Julious, S., Jaki, T., Wason, J., Mander, A., Weir, C., Koenig, F., Walton, M., Biggs, K., Nicholl, J., Hamasaki, T., Proschan, M., Scott, J., Ando, Y., Hind, D. and Altman, D.
(2018)
Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design.
BMC Medicine, 16 (210).
ISSN 1741-7015
doi: https://doi.org/10.1186/s12916-018-1196-2
Kimani, P. K., Todd, S., Renfro, L. A. and Stallard, N.
(2018)
Point estimation following two-stage adaptive threshold
enrichment clinical trials.
Statistics in Medicine, 37 (22).
pp. 3179-3196.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.7831
Weech, M., Altowaijri, H., Mayneris-Perxachs, J., Vafeiadou, K., Madden, J., Todd, S., Jackson, K. G., Lovegrove, J. A. and Yaqoob, P.
(2018)
Replacement of dietary saturated fat with unsaturated fats increases numbers of circulating endothelial progenitor cells and decreases number of microparticles: findings from the randomized, controlled DIVAS study.
American Journal of Clinical Nutrition, 107 (6).
pp. 876-882.
ISSN 0002-9165
doi: https://doi.org/10.1093/ajcn/nqy018
Howard, D. R., Brown, J. M., Todd, S. and Gregory, W. M.
(2018)
Recommendations on multiple testing adjustment in multi-arm trials with a shared control group.
Statistical Methods in Medical Research, 27 (5).
pp. 1513-1530.
ISSN 0962-2802
doi: https://doi.org/10.1177/0962280216664759
Enani, S., Przemska-Kosicka, A., Childs, C. E., Maidens, C., Dong, H., Conterno, L., Tuohy, K., Todd, S., Gosney, M. and Yaqoob, P.
(2018)
Impact of ageing and a synbiotic on the immune response to seasonal influenza vaccination; a randomised controlled trial.
Clinical Nutrition, 37 (2).
pp. 443-451.
ISSN 0261-5614
doi: https://doi.org/10.1016/j.clnu.2017.01.011
Przemska-Kosicka, A., Childs, C. E., Maidens, C., Dong, H., Todd, S., Gosney, M. A., Tuohy, K. M. and Yaqoob, P.
(2018)
Age-related changes in the natural killer cell response to seasonal influenza vaccination are not influenced by a synbiotic; a randomised controlled trial.
Frontiers in Immunology, 9.
591.
ISSN 1664-3224
doi: https://doi.org/10.3389/fimmu.2018.00591
Dimier, N. and Todd, S.
(2017)
An investigation into the two-stage meta-analytic copula modelling approach for evaluating time-to-event surrogate endpoints which comprise of one or more events of interest.
Pharmaceutical Statistics, 16 (5).
pp. 322-333.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.1812
Markey, O., Vasilopoulou, D., Kliem, K. E., Koulman, A., Fagan, C. C., Summerhill, K., Wang, L. Y., Grandison, A. S., Humphries, D. J., Todd, S., Jackson, K. G., Givens, D. I. and Lovegrove, J. A.
(2017)
Plasma phospholipid fatty acid profile confirms compliance to a novel saturated fat-reduced, monounsaturated fat-enriched dairy product intervention in adults at moderate cardiovascular risk: a randomized controlled trial.
Nutrition journal, 16 (1).
33.
ISSN 1475-2891
doi: https://doi.org/10.1186/s12937-017-0249-2
Kunz, C. U., Stallard, N., Parsons, N., Todd, S. and Friede, T.
(2017)
Blinded versus unblinded estimation of a correlation
coefficient to inform interim design adaptations.
Biometrical Journal, 59 (2).
pp. 344-357.
ISSN 0323-3847
doi: https://doi.org/10.1002/bimj.201500233
Przemska-Kosicka, A., Childs, C. E., Enani, S., Maidens, C., Dong, H., Dayel, I. B., Tuohy, K., Todd, S., Gosney, M. A. and Yaqoob, P.
(2016)
Effect of a symbiotic on the response to seasonal influenza vaccination is strongly influenced by degree of immunosenescence.
Immunity & Aging, 13 (1).
6.
ISSN 1742-4933
doi: https://doi.org/10.1186/s12979-016-0061-4
Dimairo, M., Julious, S. A., Todd, S., Nicholl, J. P. and Boote, J.
(2015)
Cross-sector surveys assessing perceptions of key stakeholders towards barriers, concerns and facilitators to the appropriate use of adaptive designs in confirmatory trials.
Trials, 16 (1).
585.
ISSN 1745-6215
doi: https://doi.org/10.1186/s13063-015-1119-x
Stevely, A., Dimairo, M., Todd, S., Julious, S. A., Nicholl, J., Hind, D. and Cooper, C. L.
(2015)
An investigation of the shortcomings of the CONSORT 2010 statement for the reporting of group sequential randomised controlled trials: a methodological systematic review.
PLoS ONE, 10 (11).
e0141104.
ISSN 1932-6203
doi: https://doi.org/10.1371/journal.pone.0141104
Stallard, N., Kunz, C. U., Todd, S., Parsons, N. and Friede, T.
(2015)
Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial.
Statistics in Medicine, 34 (23).
pp. 3104-3115.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.6567
Dimairo, M., Boote, J., Julious, S. A., Nicholl, J. P. and Todd, S.
(2015)
Missing steps in a staircase: a qualitative study of the perspectives of key stakeholders on the use of adaptive designs in confirmatory trials.
Trials, 16 (1).
430.
ISSN 1745-6215
doi: https://doi.org/10.1186/s13063-015-0958-9
Siqueira, A. L., Todd, S. and Whitehead, A.
(2015)
Sample size considerations in active-control non-inferiority trials with binary data based on the odds ratio.
Statistical Methods in Medical Research, 24 (4).
pp. 453-461.
ISSN 0962-2802
doi: https://doi.org/10.1177/0962280214520729
Kimani, P. K., Todd, S. and Stallard, N.
(2015)
Estimation after subpopulation selection in adaptive seamless trials.
Statistics in Medicine, 34 (18).
pp. 2581-2601.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.6506
Vafeiadou, K., Weech, M., Altowaijri, H., Todd, S., Yaqoob, P., Jackson, K. G.
ORCID: https://orcid.org/0000-0002-0070-3203 and Lovegrove, J. A.
(2015)
Replacement of saturated with unsaturated fats had no impact on vascular function but beneficial effects on lipid biomarkers, E-selectin and blood pressure: results from the randomized, controlled Dietary Intervention and VAScular function (DIVAS) study.
American Journal of Clinical Nutrition, 102 (1).
pp. 40-48.
ISSN 0002-9165
doi: https://doi.org/10.3945/ajcn.114.097089
Cohen, D. R., Todd, S., Gregory, W. M. and Brown, J. M.
(2015)
Adding a treatment arm to an ongoing clinical trial: a review of methodology and practice.
Trials, 16.
179.
ISSN 1745-6215
doi: https://doi.org/10.1186/s13063-015-0697-y
Kunz, C. U., Friede, T., Parsons, N., Todd, S. and Stallard, N.
(2015)
A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints.
Journal of Biopharmaceutical Statistics, 25 (1).
pp. 170-189.
ISSN 1054-3406
doi: https://doi.org/10.1080/10543406.2013.840646
Wu, S.-Y., Mayneris-Perxachs, J., Lovegrove, J. A., Todd, S. and Yaqoob, P.
(2014)
Fish oil supplementation alters numbers of circulating endothelial progenitor cells and micro particles independent of eNOS genotype.
American Journal of Clinical Nutrition, 100 (5).
pp. 1232-1243.
ISSN 1938-3207
doi: https://doi.org/10.3945/ajcn.114.088880
Weech, M., Vafeiadou, K., Hasaj, M., Todd, S., Yaqoob, P., Jackson, K. G. and Lovegrove, J. A.
(2014)
Development of a food-exchange model to replace saturated fat with MUFAS and n-6 PUFAS in adults at moderate cardiovascular risk.
Journal of Nutrition, 144 (6).
pp. 846-855.
ISSN 1541-6100
doi: https://doi.org/10.3945/jn.114.190645
Kimani, P., Todd, S. and Stallard, N.
(2014)
A comparison of methods for constructing confidence intervals after phase II/III clinical trials.
Biometrical Journal, 56 (1).
pp. 107-128.
ISSN 0323-3847
doi: https://doi.org/10.1002/bimj.201300036
Kunz, C. U., Friede, T., Parsons, N., Todd, S. and Stallard, N.
(2014)
Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data.
Pharmaceutical Statistics, 13 (4).
pp. 238-246.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.1619
Kimani, P. K., Todd, S. and Stallard, N.
(2013)
Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility.
Statistics in Medicine, 32 (17).
pp. 2893-2910.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.5757
Chapman, C.M.C., Gibson, G.R., Todd, S. and Rowland, I.
(2013)
Comparative in vitro inhibition of urinary tract pathogens by single- and multi-strain probiotics.
European Journal of Nutrition, 52 (6).
pp. 1669-1677.
ISSN 1436-6215
doi: https://doi.org/10.1007/s00394-013-0501-2
Todd, S., Baksh, M. F. and Whitehead, J.
(2012)
Sequential methods for pharmacogenetic studies.
Computational Statistics & Data Analysis, 56 (5).
pp. 1221-1231.
ISSN 0167-9473
doi: https://doi.org/10.1016/j.csda.2011.02.019
Todd, S., Valdes-Marquez, E. and West, J.
(2012)
A practical comparison of blinded methods for sample size reviews in survival data clinical trials.
Pharmaceutical Statistics, 11 (2).
pp. 141-148.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.516
Vafeiadou, K., Weech, M., Sharma, V., Yaqoob, P., Todd, S., Williams, C., Jackson, K. and Lovegrove, J.
(2012)
A review of the evidence for the effects of total dietary fat, SFA, MUFA and n-6 PUFA on vascular function, endothelial progenitor cells and microparticles.
British Journal of Nutrition, 107 (3).
pp. 303-324.
ISSN 1475-2662
doi: https://doi.org/10.1017/S0007114511004764
Parsons, N., Friede, T., Todd, S., Marquez, E. V., Chataway, J., Nicholas, R. and Stallard, N.
(2012)
An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection.
Computational Statistics & Data Analysis, 56 (5).
pp. 1150-1160.
ISSN 0167-9473
doi: https://doi.org/10.1016/j.csda.2010.10.027
Stallard, N. and Todd, S.
(2011)
Seamless phase II/III designs.
Statistical Methods in Medical Research, 20 (6).
pp. 623-634.
ISSN 0962-2802
doi: https://doi.org/10.1177/0962280210379035
Friede, T., Parsons, N., Stallard, N., Todd, S., Valdes Marquez, E., Chataway, J. and Nicholas, R.
(2011)
Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis.
Statistics in Medicine, 30 (13).
pp. 1528-1540.
ISSN 1097-0258
doi: https://doi.org/10.1002/sim.4202
O'Kelly, M., Julious, S. A., Pyke, S., Day, S., Todd, S., Seldrup, J. and Matcham, J.
(2011)
Making available information from studies sponsored by the pharmaceutical industry: some current practices.
Pharmaceutical Statistics, 10 (1).
pp. 60-69.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.430
Matcham, J., Julious, S., Pyke, S., O'Kelly, M., Todd, S., Seldrup, J. and Day, S.
(2011)
Proposed best practice for statisticians in the reporting and publication of pharmaceutical industry-sponsored clinical trials.
Pharmaceutical Statistics, 10 (1).
pp. 70-73.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.417
Pyke, S., Julious, S. A., Day, S., O'Kelly, M., Todd, S., Matcham, J. and Seldrup, J.
(2011)
The potential for bias in reporting of industry-sponsored clinical trials.
Pharmaceutical Statistics, 10 (1).
pp. 74-79.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.429
Chataway, J., Nicholas, R., Todd, S., Miller, D. H., Parsons, N., Valdes-Marquez, E., Stallard, N. and Friede, T.
(2011)
A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis.
Multiple Sclerosis Journal, 17 (1).
pp. 81-88.
ISSN 1477-0970
doi: https://doi.org/10.1177/1352458510382129
Whitehead, J., Branson, M. and Todd, S.
(2010)
A combined score test for binary and ordinal endpoints from clinical trials.
Statistics in Medicine, 29 (5).
pp. 521-532.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.3822
Friede, T., Nicholas, R., Stallard, N., Todd, S. C., Parsons, N., Valdes-Marquez, E. and Chataway, J.
(2010)
Refinement of the Clinical Scenario Evaluation Framework for Assessment of Competing Development Strategies with an Application to Multiple Sclerosis.
Drug Information Journal, 44 (6).
pp. 713-718.
ISSN 0092-8615
Siqueira, A.L., Whitehead, A. and Todd, S.
(2008)
Active-control trials with binary data: a comparison of methods for testing superiority or non-inferiority using the odds ratio.
Statistics in Medicine, 27 (3).
pp. 353-370.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.2975
Stallard, N., Todd, S. and Whitehead, J.
(2008)
Estimation following selection of the largest of two normal means.
Journal of Statistical Planning and Inference, 138 (6).
pp. 1629-1638.
ISSN 0378-3758
doi: https://doi.org/10.1016/j.jspi.2007.05.045
Whitehead, A. , Whitehead, J. , Todd, S., Zhou, Y. and Smith, M.
(2008)
Fitting models for the joint action of two drugs using SAS(R).
Pharmaceutical Statistics, 7 (4).
pp. 272-284.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.312
Todd, S.
(2007)
A 25-year review of sequential methodology in clinical studies.
Stat Med, 26 (2).
pp. 237-52.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.2763
Baksh, M.F., Haars, G., Todd, S., Van Noord, P.A.H. and Whitehead, J.
(2006)
Comparing correlations of continuous observations from two independent populations using a sequential approach.
Statistics in Medicine, 25 (24).
pp. 4293-4310.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.2676
Baksh, M. F., Todd, S., Whitehead, J. and Lucini, M. M.
(2005)
Design considerations in the sequential analysis of matched case–control data.
Statistics in Medicine, 24 (6).
pp. 853-867.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.1968
Perkins, G.D., Barrett, H., Bullock, I. , Gabbott, D.A., Todd, S. and Bion, J.F.
(2005)
The Acute Care Undergraduate TEaching (ACUTE) initiative: consensus development of core competencies in acute care for undergraduates in the United Kingdom.
Intensive Care Medicine, 31 (12).
pp. 1627-1633.
ISSN 0342-4642
doi: https://doi.org/10.1007/s00134-005-2837-4
Siqueira, A., Whitehead, A., Todd, S. and Lucini, M.
(2005)
Comparison of sample size formulae for 2x2 cross-over designs applied to bioequivalence studies.
Pharmaceutical Statistics, 4 (4).
pp. 233-243.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.183
Stallard, N. and Todd, S.
(2005)
Point estimates and confidence regions for sequential trials involving selection.
Journal of Statistical Planning and Inference, 135 (1).
pp. 402-419.
ISSN 0378-3758
doi: https://doi.org/10.1016/j.jspi.2004.05.006
Rogers, M. S., Chang, A. M. Z. and Todd, S.
(2005)
Using group-sequential analysis to achieve the optimal sample size.
Bjog-an International Journal of Obstetrics and Gynaecology, 112 (5).
pp. 529-533.
ISSN 1470-0328
doi: https://doi.org/10.1111/j.1471-0528.2005.00479.x
Kelly, P.J., Stallard, N. and Todd, S.
(2005)
An adaptive group sequential design for phase II/III clinical trials that select a single treatment from several.
Journal of Biopharmaceutical Statistics, 15 (4).
pp. 641-658.
ISSN 1054-3406
doi: https://doi.org/10.1081/BIP-200062857
Todd, S. and Stallard, N.
(2005)
A new clinical trial design combining phases II and III: sequential designs with treatment selection and a change of endpoint.
Drug Information Journal, 39.
pp. 109-118.
ISSN 0092-8615
Kelly, P.J., Sooriyarachchi, M.R., Stallard, N. and Todd, S.
(2005)
A practical comparison of group-sequential and adaptive designs.
Journal of Biopharmaceutical Statistics, 15 (4).
pp. 719-738.
ISSN 1054-3406
doi: https://doi.org/10.1081/BIP-200062859
Whitehead, J. and Todd, S.
(2004)
The double triangular test in practice.
Pharmaceutical Statistics, 3 (1).
pp. 39-49.
ISSN 1539-1612
doi: https://doi.org/10.1002/pst.91
Elliot, J.M., Virankabutra, T., Jones, S., Tanudsintum, S., Lipkin, G., Todd, S. and Bion, J.
(2003)
Erythropoietin mimics the acute phase response in critical illness.
Clinical Care, 7.
R35-R40.
ISSN 1364-8535
doi: https://doi.org/10.1186/cc2185
Stallard, N. and Todd, S.
(2003)
Sequential designs for phase III clinical trials incorporating treatment selection.
Statistics in Medicine, 22 (5).
pp. 689-703.
ISSN 0277-6715
doi: https://doi.org/10.1002/sim.1362
Todd, S.
(2003)
An adaptive approach to implementing bivariate group sequential clinical trial designs.
Journal of Biopharmaceutical Statistics, 13 (4).
pp. 605-619.
ISSN 1054-3406
doi: https://doi.org/10.1081/BIP-120024197
Vincent, E., Todd, S. and Whitehead, J.
(2002)
A sequential procedure for comparing two experimental treatments with a control.
Journal of Biopharmaceutical Statistics, 12 (2).
pp. 249-265.
ISSN 1054-3406
doi: https://doi.org/10.1081/BIP-120015747
Stallard, N., Whitehead, J., Todd, S. and Whitehead, A.
(2001)
Stopping rules for phase II studies.
British Journal of Clinical Pharmacology, 51 (6).
pp. 523-529.
ISSN 0306-5251
doi: https://doi.org/10.1046/j.0306-5251.2001.01381.x
Todd, S., Whitehead, A., Stallard, N. and Whitehead, J.
(2001)
Interim analyses and sequential designs in phase III studies.
British Journal of Clinical Pharmacology, 51 (5).
pp. 394-399.
ISSN 0306-5251
doi: https://doi.org/10.1046/j.1365-2125.2001.01382.x
Whitehead, J., Zhou, Y., Stallard, N., Todd, S. and Whitehead, A.
(2001)
Learning from previous responses in phase I dose-escalation studies.
British Journal of Clinical Pharmacology, 52 (1).
pp. 1-7.
ISSN 03065251
doi: https://doi.org/10.1046/j.0306-5251.2001.01383.x
Whitehead, J., Whitehead, A., Todd, S., Bolland, K. and Sooriyarachchi, M. R.
(2001)
Mid-trial design reviews for sequential clinical trials.
Statistics in Medicine, 20 (2).
pp. 165-176.
ISSN 0277-6715
doi: https://doi.org/10.1002/1097-0258(20010130)20:2<165::AID-SIM649>3.0.CO;2-A
Johnson, C. D., Puntis, M., Davidson, N., Todd, S. and Bryce, R.
(2001)
Randomized, dose-finding phase III study of lithium gamolenate in patients with advanced pancreatic adenocarcinoma.
British Journal of Surgery, 88 (5).
pp. 662-668.
ISSN 0007-1323
doi: https://doi.org/10.1046/j.0007-1323.2001.01770.x
Todd, S. and Sahdra, M.
(2001)
A case study of the effect of covariate adjustment in a sequential survival clinical trial.
Journal of Biopharmaceutical Statistics, 11 (4).
pp. 297-311.
ISSN 1054-3406
doi: https://doi.org/10.1081/BIP-120008850
Whitehead, J., Todd, S. and Hall, W. J.
(2000)
Confidence intervals for secondary parameters following a sequential test.
Journal of the Royal Statistical Society: Series B (Statistical Methodology), 62 (4).
pp. 731-745.
ISSN 1369-7412
doi: https://doi.org/10.1111/1467-9868.00260
Stallard, N. and Todd, S.
(2000)
Exact sequential tests for single samples of discrete responses using spending functions.
Statistics in Medicine, 19 (22).
pp. 3051-3064.
ISSN 0277-6715
doi: https://doi.org/10.1002/1097-0258(20001130)19:22<3051::AID-SIM604>3.0.CO;2-E
Todd, S., Woodward, M., Tunstall-Pedoe, H. and Bolton-Smith, C.
(1999)
Dietary Antioxidant vitamins and Fiber in the Etiology of Cardiovascular Disease and All-Causes Mortality: Results from the Scottish Heart Health Study.
American Journal of Epidemiology, 150 (10).
pp. 1073-1080.
ISSN 0002-9262
doi: https://doi.org/10.1093/oxfordjournals.aje.a009931
Todd, S.
(1999)
Sequential designs for monitoring Two Endpoints in a clinical trial.
Therapeutic Innovation & Regulatory Science, 33 (2).
pp. 417-426.
ISSN 2168-4790
doi: https://doi.org/10.1177/009286159903300213
Todd, S. and Whitehead, J.
(1997)
Confidence interval calculation for a sequential clinical trial of binary responses.
Biometrika.
ISSN 0006-3444
Todd, S.
(1997)
Incorporation of sequential trials into a fixed effects meta-analysis.
Statistics in Medicine, 16 (24).
pp. 2915-2925.
ISSN 0277-6715
doi: https://doi.org/10.1002/(SICI)1097-0258(19971230)16:24<2915::AID-SIM688>3.0.CO;2-0
Todd, S., Whitehead, J. and Facey, K.
(1996)
Point and interval estimation following a sequential clinical trial.
Biometrika.
ISSN 0006-3444
Todd, S., Woodward, M., Bolton-Smith, C. and Tunstall-Pedoe, H.
(1995)
An investigation of the relationship between antioxidant vitamin intake and coronary heart disease in men and women using discriminant analysis.
Journal of Clinical Epidemiology, 48 (2).
pp. 297-305.
ISSN 08954356
doi: https://doi.org/10.1016/0895-4356(94)00177-R
Todd, S., Woodward, M. and Bolton-Smith, C.
(1995)
An investigation of the relationship between antioxidant vitamin intake and coronary heart disease in men and women using logistic regression analysis.
Journal of Clinical Epidemiology, 48 (2).
pp. 307-316.
ISSN 08954356
doi: https://doi.org/10.1016/0895-4356(94)00178-S
Report
Branson, M., Todd, S. and Whitehead, J.,
(2004)
Estimating the covariances between efficient score test statistics in comparative studies.
Applied Statistics Technical Report. 04/2.
The University of Reading
Siqueira, A.L., Whitehead, A., Todd, S. and Lucini, M.M.,
(2004)
On sample size calculations for 2x2 cross-over designs applied to bioequivalence studies.
Applied Statistics Technical Report. 04/4.
The University of Reading
Kelly, P., Stallard, N. and Todd, S.,
(2003)
An adaptive group sequential design for clinical trials that involve treatment selection.
Applied Statistics Technical Report. 03/1.
The University of Reading
This list was generated on Thu Jun 1 11:13:06 2023 UTC.