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Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis

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Friede, T., Parsons, N., Stallard, N., Todd, S. ORCID: https://orcid.org/0000-0002-9981-923X, Valdes Marquez, E., Chataway, J. and Nicholas, R. (2011) Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis. Statistics in Medicine, 30 (13). pp. 1528-1540. ISSN 1097-0258

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To link to this item DOI: 10.1002/sim.4202


Item Type:Article
Refereed:Yes
Divisions:Science > School of Mathematical, Physical and Computational Sciences > Department of Mathematics and Statistics > Applied Statistics
Science > School of Mathematical, Physical and Computational Sciences > Department of Mathematics and Statistics
ID Code:23387
Uncontrolled Keywords:adaptive seamless design; closed test procedure; combination test; short-term endpoint; surrogate endpoint
Publisher:Wiley
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