Accessibility navigation

All-or-none (or something in between) transition of DNA

Hayashi, Y. (2004) All-or-none (or something in between) transition of DNA. Europhysics Letters, 68 (4). pp. 536-542. ISSN 0295-5075

Text - Accepted Version
· Please see our End User Agreement before downloading.


It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.1209/epl/i2004-10246-x


DNA compaction can be caused by multivalent ions as condensing agents. Both discontinuous (all-or-none) and continuous (pearl-necklace structure) transitions have been observed in experiments as the concentration of the condensing agent was increased. We have investigated the DNA transition by analytical calculations in the infinite-chain limit. A mechanism for pearl-necklace structures could be a combinatorial entropy term, which favours a mixture of globules and coils in a single chain. However, when a surface term is taken into account, it gives rise to a discontinuous transition. We also consider the role of surface charges on the globule.

Item Type:Article
Divisions:Life Sciences > School of Biological Sciences > Department of Bio-Engineering
ID Code:30821
Publisher:Institute of Physics Publishing


Downloads per month over past year

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation