Atlas of coronavirus replicase structureNeuman, B. W., Chamberlain, P., Bowden, F. and Joseph, J. (2013) Atlas of coronavirus replicase structure. Virus research, 194. pp. 49-66. ISSN 1872-7492 Full text not archived in this repository. It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing. To link to this item DOI: 10.1016/j.virusres.2013.12.004 Abstract/SummaryThe international response to SARS-CoV has produced an outstanding number of protein structures in a very short time. This review summarizes the findings of functional and structural studies including those derived from cryoelectron microscopy, small angle X-ray scattering, NMR spectroscopy, and X-ray crystallography, and incorporates bioinformatics predictions where no structural data is available. Structures that shed light on the function and biological roles of the proteins in viral replication and pathogenesis are highlighted. The high percentage of novel protein folds identified among SARS-CoV proteins is discussed.
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