1. Adesnik H and Scanziani M (2010) Lateral competition for cortical space by layer-specific horizontal
circuits. Nature 464:1155-1160.
2. Avermann M, Tomm C, Mateo C, Gerstner W, Petersen CC (2012) Microcircuits of excitatory and
inhibitory neurons in layer 2/3 of mouse barrel cortex. J Neurophysiol 107:3116-3134.
3. Bandyopadhyay S, Shamma SA, Kanold PO (2010) Dichotomy of functional organization in the mouse
auditory cortex. Nat Neurosci 13:361-368.
4. Barbour DL and Callaway EM (2008) Excitatory local connections of superficial neurons in rat auditory
cortex. J Neurosci 28:11174-11185.
5. Bender KJ, Rangel J, Feldman DE (2003) Development of columnar topography in the excitatory layer 4 to
layer 2/3 projection in rat barrel cortex. J Neurosci 23:8759-8770.
6. Benedetti BL, Takashima Y, Wen JA, Urban-Ciecko J, Barth AL (2012) Differential Wiring of Layer 2/3
Neurons Drives Sparse and Reliable Firing During Neocortical Development. Cereb Cortex, 11:2690-9.
7. Brown SP and Hestrin S (2009) Cell-type identity: a key to unlocking the function of neocortical circuits.
8. Bruno RM, Hahn TT, Wallace DJ, de Kock CP, Sakmann B (2009) Sensory experience alters specific
branches of individual corticocortical axons during development. J Neurosci 29:3172-3181.
9. Bureau I, von Saint PF, Svoboda K (2006) Interdigitated paralemniscal and lemniscal pathways in the
mouse barrel cortex. PLoS Biol 4:e382.
10. Chen JL, Carta S, Soldado-Magraner J, Schneider BL, Helmchen F (2013) Behaviour-dependent
recruitment of long-range projection neurons in somatosensory cortex. Nature 499:336-340.
11. Cho RH, Segawa S, Mizuno A, Kaneko T (2004) Intracellularly labeled pyramidal neurons in the cortical
areas projecting to the spinal cord. I. Electrophysiological properties of pyramidal neurons. Neurosci Res
50:381-394.
12. Dantzker JL and Callaway EM (2000) Laminar sources of synaptic input to cortical inhibitory interneurons
and pyramidal neurons. Nat Neurosci 3:701-707.
13. De Kock CPJ and Sakmann B (2009) Spiking in primary somatosensory cortex during natural whisking in
awake head-restrained rats is cell-type specific. Proc Natl Acad Sci USA 106:16446–50
14. Diamond ME, Huang W, Ebner FF (1994) Laminar comparison of somatosensory cortical plasticity.
Science 265:1885-1888.
15. Diamond ME, von Heimendahl M, Knutsen PM, Kleinfeld D, Ahissar E (2008) 'Where' and 'what' in the
whisker sensorimotor system. Nat Rev Neurosci 9:601-612.
16. Douglas RJ and Martin KA (2004) Neuronal circuits of the neocortex. Annu Rev Neurosci 27:419-451.
17. Douglas RJ and Martin KA (2007) Mapping the matrix: the ways of neocortex. Neuron 56:226-238.
20
18. Feldman DE and Brecht M (2005) Map plasticity in somatosensory cortex. Science 310:810-815.
19. Feldmeyer D (2012) Excitatory neuronal connectivity in the barrel cortex. Front Neuroanat 6:24.
20. Feldmeyer D, Brecht M, Helmchen F, Petersen CC, Poulet JF, Staiger JF, Luhmann HJ, Schwarz C (2013)
Barrel cortex function. Prog Neurobiol 103:3-27.
21. Feldmeyer D, Lubke J, Sakmann B (2006) Efficacy and connectivity of intracolumnar pairs of layer 2/3
pyramidal cells in the barrel cortex of juvenile rats. J Physiol (Lond ) 575:583-602.
22. Feldmeyer D, Lübke J, Silver RA, Sakmann B (2002) Synaptic connections between layer 4 spiny neuronelayer
2/3 pyramidal cell pairs in juvenile rat barrel cortex: physiology and anatomy of interlaminar
signalling within a cortical column. J Physiol (Lond ) 538:803-822.
23. Finnerty GT, Roberts LS, Connors BW (1999) Sensory experience modifies the short-term dynamics of
neocortical synapses. Nature 400:367-371.
24. Fino E, Packer AM, Yuste R (2013) The logic of inhibitory connectivity in the neocortex. Neuroscientist
19:228-237.
25. Gottlieb JP and Keller A (1997) Intrinsic circuitry and physiological properties of pyramidal neurons in rat
barrel cortex. Exp Brain Res 115:47-60.
26. Guic-Robles E, Jenkins WM, Bravo H (1992) Vibrissal roughness discrimination is barrelcortex-dependent.
Behav Brain Res 48:145-152.
27. Harris JA, Petersen RS, Diamond ME (1999) Distribution of tactile learning and its neural basis. Proc Natl
Acad Sci USA 96:7587-7591.
28. Holmgren C, Harkany T, Svennenfors B, Zilberter Y (2003) Pyramidal cell communication within local
networks in layer 2/3 of rat neocortex. J Physiol (Lond ) 551:139-153.
29. Houweling AR and Brecht M (2008) Behavioural report of single neuron stimulation in somatosensory
cortex. Nature 451:65-68.
30. Kampa BM, Letzkus JJ, Stuart GJ (2006) Cortical feed-forward networks for binding different streams of
sensory information. Nat Neurosci 9:1472-1473.
31. Kerr JN, de Kock CP, Greenberg DS, Bruno RM, Sakmann B, Helmchen F (2007) Spatial organization of
neuronal population responses in layer 2/3 of rat barrel cortex. J Neurosci 27:13316-13328.
32. Ko H, Hofer SB, Pichler B, Buchanan KA, Sjostrom PJ, Mrsic-Flogel TD (2011) Functional specificity of
local synaptic connections in neocortical networks. Nature 473:87-91.
33. Kötter R, Schubert D, Dyhrfjeld-Johnsen J, Luhmann HJ, Staiger JF (2005) Optical release of caged
glutamate for stimulation of neurons in the in vitro slice preparation. J Biomed Opt 10:11003.
34. Larkman A and Mason A (1990) Correlations between morphology and electrophysiology of pyramidal
neurons in slices of rat visual cortex. I. Establishment of cell classes. J Neurosci 10:1407-1414.
35. Larsen DD and Callaway EM (2006) Development of layer-specific axonal arborizations in mouse primary
somatosensory cortex. J Comp Neurol 494:398-414.
36. Lefort S, Tomm C, Floyd Sarria JC, Petersen CC (2009) The excitatory neuronal network of the C2 barrel
column in mouse primary somatosensory cortex. Neuron 61:301-316.
37. Lein ES, Hawrylycz MJ, Ao N, Ayres M, Bensinger A, Bernard A, Boe AF, Boguski MS, Brockway KS,
Byrnes EJ, Chen L, Chen L, Chen TM, Chin MC, Chong J, Crook BE, Czaplinska A, Dang CN, Datta S,
Dee NR, Desaki AL, Desta T, Diep E, Dolbeare TA, Donelan MJ, Dong HW, Dougherty JG, Duncan BJ,
Ebbert AJ, Eichele G, Estin LK, Faber C, Facer BA, Fields R, Fischer SR, Fliss TP, Frensley C, Gates SN,
Glattfelder KJ, Halverson KR, Hart MR, Hohmann JG, Howell MP, Jeung DP, Johnson RA, Karr PT,
Kawal R, Kidney JM, Knapik RH, Kuan CL, Lake JH, Laramee AR, Larsen KD, Lau C, Lemon TA, Liang
AJ, Liu Y, Luong LT, Michaels J, Morgan JJ, Morgan RJ, Mortrud MT, Mosqueda NF, Ng LL, Ng R, Orta
GJ, Overly CC, Pak TH, Parry SE, Pathak SD, Pearson OC, Puchalski RB, Riley ZL, Rockett HR, Rowland
SA, Royall JJ, Ruiz MJ, Sarno NR, Schaffnit K, Shapovalova NV, Sivisay T, Slaughterbeck CR, Smith SC,
Smith KA, Smith BI, Sodt AJ, Stewart NN, Stumpf KR, Sunkin SM, Sutram M, Tam A, Teemer CD,
Thaller C, Thompson CL, Varnam LR, Visel A, Whitlock RM, Wohnoutka PE, Wolkey CK, Wong VY,
Wood M, Yaylaoglu MB, Young RC, Youngstrom BL, Yuan XF, Zhang B, Zwingman TA, Jones AR
(2007) Genome-wide atlas of gene expression in the adult mouse brain. Nature 445:168-176.
38. Lübke J, Roth A, Feldmeyer D, Sakmann B (2003) Morphometric analysis of the columnar innervation
domain of neurons connecting layer 4 and layer 2/3 of juvenile rat barrel cortex. Cereb Cortex 13:1051-
1063.
39. Mason A and Larkman A (1990) Correlations between morphology and electrophysiology of pyramidal
neurons in slices of rat visual cortex. II. Electrophysiology. J Neurosci 10:1415-1428.
40. Molnar Z and Cheung AF (2006) Towards the classification of subpopulations of layer V pyramidal
projection neurons. Neurosci Res 55:105-115.
41. Mountcastle VB (1997) The columnar organization of the neocortex. Brain 120 ( Pt 4):701-722.
42. Murayama M, Perez-Garci E, Nevian T, Bock T, Senn W, Larkum ME (2009) Dendritic encoding of
sensory stimuli controlled by deep cortical interneurons. Nature 457:1137-1141.
43. Oberlaender M, de Kock CPJ, Bruno RM, Ramirez A, Meyer HS, Dercksen VJ, Helmstaedter M, Sakmann
B (2012) Cell Type–Specific Three-Dimensional Structure of Thalamocortical Circuits in a Column of Rat
Vibrissal CortexCereb. Cortex 22 (10): 2375-2391
44. Ohki K, Chung S, Ch'ng YH, Kara P, Reid RC (2005) Functional imaging with cellular resolution reveals
precise micro-architecture in visual cortex. Nature 433:597-603.
45. Otsuka T and Kawaguchi Y (2008) Firing-pattern-dependent specificity of cortical excitatory feed-forward
subnetworks. J Neurosci 28:11186-11195.
46. Paxinos G and Watson C (1998) The rat brain in stereotaxic coordinates. San Diego: Academic Press.
47. Peters A, Kara DA (1985) The neuronal composition of area 17 of rat visual cortex. I. The pyramidal cells.
J Comp Neurol 234:218-241.
48. Petersen CC and Crochet S (2013) Synaptic computation and sensory processing in neocortical layer 2/3.
Neuron 78:28-48.
49. Petersen CC and Sakmann B (2001) Functionally independent columns of rat somatosensory barrel cortex
revealed with voltage-sensitive dye imaging. J Neurosci 21:8435-8446.
50. Rothschild G, Nelken I, Mizrahi A (2010) Functional organization and population dynamics in the mouse
primary auditory cortex. Nat Neurosci 13:353-360.
51. Sato H, Shimanuki Y, Saito M, Toyoda H, Nokubi T, Maeda Y, Yamamoto T, Kang Y (2008) Differential
columnar processing in local circuits of barrel and insular cortices. J Neurosci 28:3076-3089.
52. Sato TR and Svoboda K (2010) The functional properties of barrel cortex neurons projecting to the primary
motor cortex. J Neurosci 30:4256-4260.
53. Schubert D, Kötter R, Luhmann HJ, Staiger JF (2006) Morphology, electrophysiology and functional input
connectivity of pyramidal neurons characterizes a genuine layer va in the primary somatosensory cortex.
Cereb Cortex 16:223-236.
54. Schubert D, Kötter R, Staiger JF (2007) Mapping functional connectivity in barrel-related columns reveals
layer- and cell type-specific microcircuits. Brain Struct Funct 212:107-119.
55. Schubert D, Kötter R, Zilles K, Luhmann HJ, Staiger JF (2003) Cell type-specific circuits of cortical layer
IV spiny neurons. J Neurosci 23:2961-2970.
56. Schubert D, Staiger JF, Cho N, Kötter R, Zilles K, Luhmann HJ (2001) Layer-specific intracolumnar and
transcolumnar functional connectivity of layer V pyramidal cells in rat barrel cortex. J Neurosci 21:3580-
3592.
57. Shepherd GM, Pologruto TA, Svoboda K (2003) Circuit analysis of experience-dependent plasticity in the
developing rat barrel cortex. Neuron 38:277-289.
58. Shepherd GM, Stepanyants A, Bureau I, Chklovskii D, Svoboda K (2005) Geometric and functional
organization of cortical circuits. Nat Neurosci 8:782-790.
59. Shepherd GM and Svoboda K (2005) Laminar and columnar organization of ascending excitatory
projections to layer 2/3 pyramidal neurons in rat barrel cortex. J Neurosci 25:5670-5679.
60. Silberberg G and Markram H (2007) Disynaptic inhibition between neocortical pyramidal cells mediated
by Martinotti cells. Neuron 53:735-746.
61. Smith SL and Hausser M (2010) Parallel processing of visual space by neighboring neurons in mouse
visual cortex. Nat Neurosci 13:1144-1149.
62. Sorensen SA, Bernard A, Menon V, Royall JJ, Glattfelder KJ, Hirokawa K, Mortrud M, Miller JA, Zeng H,
Hohmann JG, Jones AR, Lein ES (2013) Correlated Gene Expression and Target Specificity Demonstrate
Excitatory Projection Neuron Diversity. Cereb Cortex, Epub ahead of print.
63. Staiger JF, Flagmeyer I, Schubert D, Zilles K, Kötter R, Luhmann HJ (2004) Functional diversity of layer
IV spiny neurons in rat somatosensory cortex: quantitative morphology of electrophysiologically
characterized and biocytin labeled cells. Cereb Cortex 14:690-701.
64. Stepanyants A, Martinez LM, Ferecsko AS, Kisvarday ZF (2009) The fractions of short- and long-range
connections in the visual cortex. Proc Natl Acad Sci U S A 106:3555-3560.
65. Sugino K, Hempel CM, Miller MN, Hattox AM, Shapiro P, Wu C, Huang ZJ, Nelson SB (2006) Molecular
taxonomy of major neuronal classes in the adult mouse forebrain. Nat Neurosci 9:99-107.
66. Thomson AM and Bannister AP (1998) Postsynaptic pyramidal target selection by descending layer III
pyramidal axons: dual intracellular recordings and biocytin filling in slices of rat neocortex. Neuroscience
84:669-683.
67. Thomson AM and Bannister AP (2003) Interlaminar connections in the neocortex. Cereb Cortex 13:5-14.
68. Thomson AM and Lamy C (2007) Functional maps of neocortical local circuitry. Front Neurosci 1:19-42.
69. van Brederode JFM, Foehring RC, Spain WJ (2000) Morphological and electrophysiological properties of
atypically oriented layer 2 pyramidal cells of the juvenile rat neocortex. Neuroscience 101:851-861.
70. Waters J, Larkum M, Sakmann B, Helmchen F (2003) Supralinear Ca2+ influx into dendritic tufts of layer
2/3 neocortical pyramidal neurons in vitro and in vivo. J Neurosci 23:8558-8567.
71. Welker C and Woolsey TA (1974) Structure of layer IV in the somatosensory neocortex of the rat:
description and comparison with the mouse. J Comp Neurol 158:437-453.
72. Wimmer VC, Bruno RM, de Kock CP, Kuner T, Sakmann B (2010) Dimensions of a projection column
and architecture of VPM and POm axons in rat vibrissal cortex. Cereb Cortex 20:2265-2276.
73. Woolsey TA and van der Loos H (1970) The structural organization of layer IV in the somatosensory
region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete
cytoarchitectonic units. Brain Res 17:205-242.
74. Yin X, Goudriaan J, Lantinga EA, Vos J, Spiertz HJ (2003) A flexible sigmoid function of determinate
growth, erratum. Ann Bot 91:753-371.
75. Yoshimura Y, Dantzker JL, Callaway EM (2005) Excitatory cortical neurons form fine-scale functional
networks. Nature 433:868-873.
76. Yu C, Derdikman D, Haidarliu S, Ahissar E (2006) Parallel Thalamic Pathways for Whisking and Touch
Signals in the Rat. PLoS Biol 4(5)