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Synthetic entry to functionalised morpholines and [1,4]-oxazepanes via reductive amination reactions of carbohydrate derived dialdehydes

Clark, S.M. and Osborn, H.M.I. (2004) Synthetic entry to functionalised morpholines and [1,4]-oxazepanes via reductive amination reactions of carbohydrate derived dialdehydes. Tetrahedron-Asymmetry, 15 (22). pp. 3643-3652. ISSN 0957-4166

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To link to this item DOI: 10.1016/j.tetasy.2004.10.002

Abstract/Summary

The rapid synthesis of functionalised morpholines and [1,4]-oxazepanes displaying up to three stereocentres, by reductive amination reactions between carbohydrate derived dialdehydes and a range of amines, is described. (C) 2004 Elsevier Ltd. All rights reserved.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
ID Code:11142
Uncontrolled Keywords:POTENT GLYCOSIDASE INHIBITORS, SELECTIVE REDUCING AGENT, GLYCOL, FISSION, RIGID SYSTEMS, D-GLUCOSE, DERIVATIVES, RING, MONOSACCHARIDES, SYNTHONS, ANALOGS

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