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Effect of Ginkgo biloba (EGb 761®) on differential gene expression

Rimbach, G. , Wolffram, S. , Watanabe, C. , Packer, L. and Gohil, K. (2003) Effect of Ginkgo biloba (EGb 761®) on differential gene expression. Pharmacopsychiatry, 36 (S1). pp. 95-99. ISSN 0176-3679

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To link to this item DOI: 10.1055/s-2003-40457

Abstract/Summary

Supplementation of diets with plant extracts such as ginkgo biloba extract (EGb 761®) (definition see editorial) for health and prevention of degenerative diseases is popular. However, it is often difficult to analyse the biological activities of plant extracts due to their complex nature and the possible synergistic and/or antagonistic effects of their components. Genome-wide expression monitoring with high-density oligonucleotide arrays provides one way to examine the molecular targets of plant extracts and may prove a useful tool in evaluating their therapeutic claims. Here, we will briefly describe some of our work on the effect of EGb 761® on differential gene expression in relation to its potential anti-carcinogenic, photoprotective and neuromodulatory properties.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences
ID Code:13043
Additional Information:2nd Biocenter Symposium on Drug Therapy - Ginkgo Biloba Extract EGb 761 in Dementia and Other Memory Disorders Frankfurt, Germany

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