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Assessment of depression, anxiety and apathy in prodromal and early Huntington disease

Vaccarino, A. L., Sills, T., Anderson, K. E., Bachoud-Lévi, A.-C., Borowsky, B., Craufurd, D., Duff, K., Giuliano, J., Groves, M., Guttman, M., Kupchak, P., Ho, A. K. ORCID: https://orcid.org/0000-0002-2581-126X, Paulsen, J. S., Pedersen, K. F., van Duijn, E., van Kammen, D. P. and Evans, K. (2011) Assessment of depression, anxiety and apathy in prodromal and early Huntington disease. PLoS Currents, 3. RRN1242. ISSN 2157-3999

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To link to this item DOI: 10.1371/currents.RRN1242

Abstract/Summary

The Functional Rating Scale Taskforce for pre-Huntington Disease (FuRST-pHD) is a multinational, multidisciplinary initiative with the goal of developing a data-driven, comprehensive, psychometrically sound, rating scale for assessing symptoms and functional ability in prodromal and early Huntington disease (HD) gene expansion carriers. The process involves input from numerous sources to identify relevant symptom domains, including HD individuals, caregivers, and experts from a variety of fields, as well as knowledge gained from the analysis of data from ongoing large-scale studies in HD using existing clinical scales. This is an iterative process in which an ongoing series of field tests in prodromal (prHD) and early HD individuals provides the team with data on which to make decisions regarding which questions should undergo further development or testing and which should be excluded. We report here the development and assessment of the first iteration of interview questions aimed to assess Depression, Anxiety and Apathy in prHD and early HD individuals.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Psychology and Clinical Language Sciences > Psychopathology and Affective Neuroscience
Life Sciences > School of Psychology and Clinical Language Sciences > Department of Psychology
Life Sciences > School of Psychology and Clinical Language Sciences > Nutrition and Health
ID Code:26360

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