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Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria

Le, T. M. V., AbuOun, M., Morrison, V., Thomson, N., James, I. C., Woodward, M. J., Nguyen, V. V. C., Jeremy, F., Constance, S. and Stephen, B. (2011) Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria. Antimicrobial Agents and Chemotherapy, 55 (4). pp. 1798-1802. ISSN 1098-6596

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To link to this article DOI: 10.1128/aac.01200-10

Abstract/Summary

The qnrS1 gene induces reduced susceptibility to fluoroquinolones in enterobacteria. We investigated the structure, antimicrobial susceptibility phenotype, and antimicrobial resistance gene characteristics of qnrS1 plasmids from hospitalized patients and community controls in southern Vietnam. We found that the antimicrobial susceptibilities, resistance gene characteristics, and plasmid structures of qnrS1 plasmids from the hospital differed from those from the community. Our data imply that the characteristics of the two plasmid groups are indicative of distinct selective pressures in the differing environments.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Food Microbial Sciences Research Group
No Reading authors. Back catalogue items
ID Code:28282
Publisher:ASM Press

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