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Priapism following a juvenile Russell’s viper bite: an unusual case report

Senthilkumaran, S., Williams, H., Patel, K., Trim, S., Thirumalaikolundusubramanian, P. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2021) Priapism following a juvenile Russell’s viper bite: an unusual case report. PLoS Neglected Tropical Diseases. ISSN 1935-2735 (In Press)

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Abstract/Summary

Following a bite from a juvenile Russell’s Viper (Daboia russelii), a priapism (painful erection) developed rapidly in a 16-year old male and only subsided after administration of antivenom three hours later. Potential mechanisms for this snakebite-induced priapism are unclear but likely due to venom toxins causing nitric oxide release and subsequent vasodilation of endothelium in the corpus cavernosum although the possible involvement of other mechanisms cannot be ruled out. We strongly believe that this unusual case report may lead to further scientific research in order to improve the clinical understanding of the pathophysiology of envenomation due to Russell’s viper bites. Although it is too early to speculate, further research may also discover the possibilities of developing venom-based candidate molecules to treat sexual dysfunction in males and females.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Biological Sciences > Biomedical Sciences
Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Division of Pharmacology
ID Code:96277
Publisher:Public Library of Science

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