Accessibility navigation

Ultrasound-guided compression method effectively counteracts Russell’s viper bite-induced pseudoaneurysm

Senthilkumaran, S., Miller, S. W., Williams, H. F., Vaiyapuri, R., Savania, R., Elangovan, N., Thirumalaikolundusubramanian, P., Patel, K. and Vaiyapuri, S. ORCID: (2022) Ultrasound-guided compression method effectively counteracts Russell’s viper bite-induced pseudoaneurysm. Toxins, 14 (4). 260. ISSN 2072-6651

Text (Open access) - Published Version
· Available under License Creative Commons Attribution.
· Please see our End User Agreement before downloading.

[img] Text - Accepted Version
· Restricted to Repository staff only


It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.3390/toxins14040260


Russell’s viper (Daboia russelii), one of the ‘Big Four’ venomous snakes in India is responsible for a majority of snakebite-induced deaths and permanent disabilities. Russell’s viper bites are known to induce bleeding/clotting abnormalities as well as myotoxic, nephrotoxic, cytotoxic and neurotoxic envenomation effects. In addition, they have been reported to induce rare envenomation effects such as priapism, sialolithiasis and splenic rupture. However, Russell’s viper bite-induced pseudoaneurysm (PA) has not been previously reported. PA or false aneurysm is a rare phenomenon that occurs in arteries following traumatic injuries includ-ing some animal bites, and it can become a life-threatening condition if not treated promptly. Here, we document two clinical cas-es of Russell’s viper bites where PA has developed despite antivenom treatment. Notably, a non-surgical procedure, ultra-sound-guided compression (USGC), either alone, or in combination with thrombin was effectively used in both the cases to treat the PA. Following this procedure and additional measures, the patients made complete recoveries without the recurrence of PA which were confirmed by subsequent examination and ultrasound scans. These data demonstrate the development of PA as a rare complication following Russell’s viper bites and the effective use of a simple, non-surgical procedure, USGC for the successful treatment of PA. These results will create awareness among healthcare professionals on the development of PA and the use of USGC in snakebite victims following Russell’s viper as well as other viper bites.

Item Type:Article
Divisions:Life Sciences > School of Biological Sciences > Biomedical Sciences
Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Division of Pharmacology
Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmacy Practice Research Group
ID Code:104762


Downloads per month over past year

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation