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Solid-state fermentation: a continuous process for fungal tannase production

van de Lagemaat, J. and Pyle, D. L. (2004) Solid-state fermentation: a continuous process for fungal tannase production. Biotechnology and Bioengineering, 87 (7). pp. 924-929. ISSN 0006-3592

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To link to this item DOI: 10.1002/bit.20206


Truly continuous solid-state fermentations with operating times of 2-3 weeks were conducted in a prototype bioreactor for the production of fungal (Penicillium glabrum) tannase from a tannin-containing model substrate. Substantial quantities of the enzyme were synthesized throughout the operating periods and (imperfect) steady-state conditions seemed to be achieved soon after start-up of the fermentations. This demonstrated for the first time the possibility of conducting solid-state fermentations in the continuous mode and with a constant noninoculated feed. The operating variables and fermentation conditions in the bioreactor were sufficiently well predicted for the basic reinoculation concept to succeed. However, an incomplete understanding of the microbial mechanisms, the experimental system, and their interaction indicated the need for more research in this novel area of solid-state fermentation. (C) 2004 Wiley Periodicals, Inc.

Item Type:Article
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences
ID Code:12908
Uncontrolled Keywords:solid-state fermentation, continuous process, bioreactor, fungi, tannin, acyl hydrolase, tannic acid, STRATEGIES

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