Interaction between attaching-effacing Escherichia coli O26:K60 and O157:H7 in young lambsAktan, I., Woodward, M. and La Ragione, R. M. (2009) Interaction between attaching-effacing Escherichia coli O26:K60 and O157:H7 in young lambs. Research in Veterinary Science, 87 (1). pp. 13-15. ISSN 0034-5288 Full text not archived in this repository. It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing. To link to this item DOI: 10.1016/j.rvsc.2008.11.006 Abstract/SummaryRecent surveys have shown that Escherichia coli O26 is prevalent in ruminants compared with E. coli O157. These serogroups share common colonisation factors and we hypothesised that prior colonisation by E. coli O26 may show reduced colonisation by E. coli O157. To test this hypothesis, strains of E. coli O26:K6O and O157:H7 were tested in competitive in vitro and in vivo studies. Using an established 6-week-old lamb model, an experimental group of lambs was dosed orally with E. coli O26:K6O and then E. coli O157:147 four days later. The faecal shedding of O26:K6O and O157:H7 organisms from this experimental group was compared with that from animals dosed with either O26:K6O alone or O157:H7 alone. Shedding data indicated that counts for O157:H7 were unaffected by the competition from O26:K6O, whereas the O26:K6O counts were lower when competing with O157:H7. (C) 2008 Elsevier Ltd. All rights reserved.
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