Naturally acquired attaching and effacing Escherichia coli in sheepWales, A. D., Pearson, G. R., Best, A., Cookson, A. L., La Ragione, R. M., Roe, J. M., Hayes, C. M. and Woodward, M. J. (2005) Naturally acquired attaching and effacing Escherichia coli in sheep. Research in Veterinary Science, 78 (2). pp. 109-115. ISSN 0034-5288 Full text not archived in this repository. It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing. To link to this item DOI: 10.1016/j.rvsc.2004.07.002 Abstract/SummaryIn a series of experiments involving the inoculation of sheep with Escherichia coli O157:H7, and subsequent detailed histopathological examination of the intestinal mucosa, attaching-effacing (AE) lesions formed by elements of the natural flora were observed in 18% of animals. These incidental AE lesions typically were small and sparse, and were not associated with clinical disease. It was possible to identify further some of the lesional bacteria, revealing that E. coli O115 had formed lesions in one of the seven affected animals, and similarly E. coli O26 had formed some of the lesions in another. As AE strains, source flocks, housing and feed sources were diverse, a common source of lesion-forming bacteria appears to be unlikely. It is postulated that subclinical AE lesions are a mechanism of persistence of AE bacteria in sheep.
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