Article

Degens, H., Patel, K. and Matsakas, A. (2025) Myostatin knockout mice have larger muscle fibres with normal function and morphology. Muscle & Nerve, 71 (6). pp. 1122-1131. ISSN 1097-4598 doi: 10.1002/mus.28389

Barlow, J., Sfyri, P. P., Mitchell, R., Verpoorten, S., Scully, D., Andreeou, C., Papadopoulos, P., Patel, K. and Matsakas, A. (2021) Platelet releasate normalises the compromised muscle regeneration in a mouse model of hyperlipidaemia. Experimental Physiology, 106 (3). pp. 700-713. ISSN 0958-0670 doi: 10.1113/EP088937

Vaughan, D., Kretz, O., Alqallaf, A., Mitchell, R., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Matsakas, A., Pasternack, A., Collins-Hooper, H., Ritvos, O., Ballesteros, R., Huber, T. B., Amthor, H., Mukherjee, A. and Patel, K. (2020) Diminution in sperm quantity and quality in mouse models of Duchenne Muscular Dystrophy induced by a myostatin-based muscle growth-promoting intervention. European Journal of Translational Myology, 30 (2). pp. 276-285. ISSN 2037-7452 doi: 10.4081/ejtm.2019.8904

Verpoorten, S., Sfryi, P., Scully, D., Mitchell, R., Tzimou, A., Mougious, V., Patel, K. and Matsakas, A. (2020) Loss of CD36 protects against diet-induced obesity but results in impaired muscle stem cell function, delayed muscle regeneration and hepatic steatosis. Acta Physiologica, 228 (3). e13395. ISSN 1748-1716 doi: 10.1111/apha.13395

Scully, D., Sfyri, P., Wilkinson, H. N., Acebes-Huerta, A., Verpoorten, S., Munoz-Turrillas, M., Parnell, A., Patel, K., Hardman, M. J., Gutierrez, L. and Matsakas, A. (2020) Optimising platelet secretomes to deliver robust tissue specific regeneration. Journal of Tissue Engineering and Regenerative Medicine, 14 (1). pp. 82-98. ISSN 1932-7005 doi: 10.1002/term.2965

Scully, D., Sfyri, P., Verpooten, S., Papadopoulos, P., Muñoz-Turrillas, M. C., Mitchell, R., Aburima, A., Patel, K., Gutierez, l., Naseem, K. M. and Matsakas, A. (2019) Platelet releasate promotes skeletal myogenesis by increasing muscle stem cell commitment to differentiation and accelerates muscle regeneration following acute injury. Acta Physiologica, 225 (3). e13207. ISSN 1748-1708 doi: 10.1111/apha.13207

Williams, H., Mellows, B., Mitchell, R., Sfyri, P., Layfield, H., Salamah, M., Vaiyapuri, R., Collins-Hooper, H., Bicknell, A., Matsakas, A., Patel, K. and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517 (2019) Mechanisms underpinning the permanent muscle damage induced by snake venom metalloprotease. PLoS Neglected Tropical Diseases, 13 (1). e0007041. ISSN 1935-2735 doi: 10.1371/journal.pntd.0007041

Alyodawi, K., Vermeij, W. P., Omairi, S., kretz, O., Hopkinson, M., Solagna, F., Joch, B., Brandt, R. M. C., Barnhoorn, S., van Vliet, N., Ridwan, Y., Essers, J., Mitchell, R., Morash, T., Pasternack, A., Ritvos, O., Matsakas, A., Collins-Hooper, H., Huber, T. B., Hoeijmakers, J. H. J. and Patel, K. (2019) Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling. Journal of Cachexia, Sarcopenia and Muscle, 10 (3). pp. 662-686. ISSN 2190-6009 doi: 10.1002/jcsm.12404

Omairi, S., Hua, K.-L., Collins-Hooper, H., Scott, C., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Torelli, S., Montanero, F., Matsakas, A. and Patel, K. (2019) Regulation of the dystrophin-associated glycoprotein complex composition by the metabolic properties of muscle fibres. Scientific Reports, 9. 2770. ISSN 2045-2322 doi: 10.1038/s41598-019-39532-4

Sfyri, P. P., Yuldasheva, N. Y., Tzimou, A., Giallourou, N., Crispi, V., Aburima, A., Beltran-Alvarez, P., Patel, K., Mougios, V., Swann, J. R., Kearney, M. T. and Matsakas, A. (2018) Attenuation of oxidative stress-induced lesions in skeletal muscle in a mouse model of obesity-independent hyperlipidaemia and atherosclerosis through the inhibition of Nox2 activity. Free Radical Biology & Medicine, 129. pp. 504-519. ISSN 0891-5849 doi: 10.1016/j.freeradbiomed.2018.10.422

Paolini, A., Omairi, S., Mitchell, R., Vaughan, D., Matsakas, A., Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517, Ricketts, T., Rubinsztein, D. C. and Patel, K. (2018) Attenuation of autophagy impacts on muscle fibre development, starvation induced stress and fibre regeneration following acute injury. Scientific Reports, 8. 9062. ISSN 2045-2322 doi: 10.1038/s41598-018-27429-7

Elashry, M. I., Matsakas, A., Wenisch, S., Arnhold, S. and Patel, K. (2017) The effect of caloric restriction on the forelimb skeletal muscle fibers of 1 the hypertrophic myostatin null mice. Acta Histochemica. ISSN 0065-1281 doi: 10.1016/j.acthis.2017.06.002

Omairi, S., Matsakas, A., Degens, H., Kretz, O., Hansson, K.-A., Våvang Solbrå, A., Bruusgaard, J., Joch, B., Sartori, R., Giallourou, N., Mitchell, R., Collins-Hooper, H., Foster, K., Pasternack, A., Ritvos, O., Sandri, M., Narkar, V., Swann, J., Huber, T. and Patel, K. (2016) Enhanced exercise and regenerative capacity in a mouse model that violates size constraints of oxidative muscle fibres. eLIFE, 5. e16940. ISSN 2050-084X doi: 10.7554/eLife.16940

Matsakas, A., Prosdocimo, D. A., Mitchell, R., Collins-Hooper, H., Giallourou, N., Swann, J. R., Potter, P., Epting, T., Jain, M. K. and Patel, K. (2015) Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse. Skeletal Muscle, 5. 38. ISSN 2044-5040 doi: 10.1186/s13395-015-0063-5

Collins-Hooper, H., Sartori, R., Macharia, R., Visanuvimol, K., Foster, K., Matsakas, A., Flasskamp, H., Ray, S., Dash, P., Sandri, M. and Patel, K. (2014) Propeptide-mediated inhibition of myostatin increases muscle mass through inhibiting proteolytic pathways in aged mice. Journals of Gerontology Series A: Biological and Medical Sciences, 69 (9). pp. 1049-1059. ISSN 1079-5006 doi: 10.1093/gerona/glt170

Matsakas, A., Romanello, V., Sartori, R., Masiero, E., Macharia, R., Otto, A., Elashry, M., Sandri, M. and Patel, K. (2012) Food restriction reverses the hyper-muscular phenotype and force generation capacity deficit of the myostatin null mouse. International Journal of Sports Medicine, 34 (3). pp. 223-231. ISSN 0172-4622 doi: 10.1055/s-0032-1312605

Otto, A., Macharia, R., Matsakas, A., Valasek, P., Mankoo, B. S. and Patel, K. (2010) A hypoplastic model of skeletal muscle development displaying reduced foetal myoblast cell numbers, increased oxidative myofibres and improved specific tension capacity. Developmental Biology, 343 (1-2). pp. 51-62. ISSN 0012-1606 doi: 10.1016/j.ydbio.2010.04.014

Matsakas, A. and Patel, K. (2009) Intracellular signalling pathways regulating the adaptation of skeletal muscle to exercise and nutritional changes. Histology and Histopathology, 24 (2). pp. 209-222. ISSN 0213-3911

Matsakas, A. (2009) Molecular advances shed light on cardiac myosin heavy chain expression in health and disease. Experimental Physiology, 94 (12). pp. 1161-1162. ISSN 0958-0670 doi: 10.1113/expphysiol.2009.050211

Matsakas, A., Foster, K., Otto, A., Macharia, R., Elashry, M. I., Feist, S., Graham, I., Foster, H., Yaworsky, P., Walsh, F., Dickson, G. and Patel, K. (2009) Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice. Neuromuscular Disorders, 19 (7). pp. 489-499. ISSN 0960-8966 doi: 10.1016/j.nmd.2009.06.367

Elashry, M. I., Otto, A., Matsakas, A., El-Morsy, S. E. and Patel, K. (2009) Morphology and myofiber composition of skeletal musculature of the forelimb in young and aged wild type and myostatin null mice. Rejuvenation Research, 12 (4). pp. 269-281. ISSN 1549-1684 doi: 10.1089/rej.2009.0870

Amthor, H., Otto, A., Vulin, A., Rochat, A., Dumonceaux, J., Garcia, L., Mouisel, E., Hourde, C., Macharia, R., Friedrichs, M., Relaix, F., Zammit, P. S., Matsakas, A., Patel, K. and Partridge, T. (2009) Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity. Proceedings of the National Academy of Sciences of the United States of America, 106 (18). pp. 7479-7484. ISSN 0027-8424 doi: 10.1073/pnas.0811129106

Matsakas, A. and Patel, K. (2009) Skeletal muscle fibre plasticity in response to selected environmental and physiological stimuli. Histology and Histopathology, 24 (5). pp. 611-629. ISSN 0213-3911

Conference or Workshop Item

Omairi, S., Matsakas, A., Torelli, S. and Patel, K. (2020) Muscle-specific expression of Erry in the Myostatin Null Background leads to the development of hypertrophied oxidative muscle. In: UNSPECIFIED. doi: 10.5339/qproc.2020.nmd.26