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Prebiotics and bowel cancer

Walton, G. E. and Gibson, G. R. (2007) Prebiotics and bowel cancer. Current Topics in Nutraceutical Research, 5 (1). pp. 19-28. ISSN 1540-7535

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Abstract/Summary

Bowel cancer is a growing malignancy, with more than a million annual cases reported worldwide. It has been suggested that there is microbial involvement in onset of the disease and that an altered composition has previously been observed in those suffering from the malignancy, compared to healthy counterparts. The use of prebiotic functional foods to modify the colonic microflora may provide a method of reducing genotoxic potential within the colon, whilst offering-Protective strategies in the form of metabolites such as butyrate. The following review highlights some of the studies that demonstrate the potentia role for prebiotics as protective factors against bowel cancer.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences
ID Code:12871
Uncontrolled Keywords:colorectal cancer, gut flora and prebiotics, ABERRANT CRYPT FOCI, HUMAN INTESTINAL MICROFLORA, HUMAN COLONIC, MICROBIOTA, FECAL BACTERIAL-FLORA, LACTIC-ACID BACTERIA, HUMAN GUT, DIETARY FIBER, HUMAN FECES, BIFIDOBACTERIUM-LACTIS, COLORECTAL ADENOMAS

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