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Using probiotics and prebiotics to improve gut health

Tuohy, K.M., Probert, H.M., Smejkal, C.W. and Gibson, G.R. (2003) Using probiotics and prebiotics to improve gut health. Drug Discovery Today, 8 (15). pp. 692-700. ISSN 1359-6446

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To link to this article DOI: 10.1016/S1359-6446(03)02746-6

Abstract/Summary

Recent molecular-based investigations have confirmed the species diversity and metabolic complexity of the human gut microbiota. It is also increasingly clear that the human gut microbiota plays a crucial role in host health, both as a source of infection and environmental insult and, conversely, in protection against disease and maintenance of gut function. Although little is known about the health impact of the dominant groups of gut bacteria it is generally accepted that bifidobacteria and lactobacilli are important components of what might be termed the beneficial gut microbiota. The microbiota management tools of probiotics, prebiotics and synbiotics have been developed and, indeed, commercialized over the past few decades with the expressed purpose of increasing numbers of bifidobacteria and/or lactobacilli within the gastrointestinal tract.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences
ID Code:12923
Uncontrolled Keywords:ANTIBIOTIC-ASSOCIATED DIARRHEA, PLACEBO-CONTROLLED TRIAL, CLOSTRIDIUM-DIFFICILE COLITIS, BIFIDOBACTERIUM-LACTIS HN019, IRRITABLE-BOWEL-SYNDROME, LACTOBACILLUS GG, DOUBLE-BLIND, SACCHAROMYCES-BOULARDII, MAINTENANCE TREATMENT, ULCERATIVE-COLITIS

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