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Mammalian-microbial cometabolism of L-Carnitine in the context of atherosclerosis

Claus, S. P. (2014) Mammalian-microbial cometabolism of L-Carnitine in the context of atherosclerosis. Cell Metabolism, 20 (5). pp. 699-700. ISSN 1550-4131

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To link to this item DOI: 10.1016/j.cmet.2014.10.014

Abstract/Summary

g-butyrobetaine has long been known as the precursor of endogenous L-carnitine synthesis. In this issue, Koeth et al. (2014) demonstrate that it is also a major metabolite of L-carnitine degradation by gut bacteria that precedes the enteric production of trimethylamine and trimethylamine-N-oxide.

Item Type:Article
Refereed:No
Divisions:Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > NMR (CAF)
Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Food Microbial Sciences Research Group
ID Code:38533
Publisher:Elsevier

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