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Comparison of cytokine production in cultures of whole human blood and purified mononuclear cells

Yaqoob, P., Newsholme, E. and Calder, P. (1998) Comparison of cytokine production in cultures of whole human blood and purified mononuclear cells. Cytokine, 11 (8). pp. 600-605. ISSN 1096-0023

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Abstract/Summary

In order to examine inter- and intra-individual variations in cytokine production, blood was collected from 48 healthy subjects on each of 4 occasions separated by 4 weeks. Whole blood (diluted 1:10) and mononuclear cell (MNC) cultures were stimulated for 24 h with either concanavalin A (Con A) or bacterial lipopolysaccharide (LPS) and the concentrations of IL-1.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
ID Code:68759
Publisher:Elsevier

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