Number of items: 14.
Article
Holbrook, L., Keeton, S., Sasikumar, P., Nock, S., Gelzinis, J., Brunt, E., Ryan, S., Pantos, M. M., Verbetsky, C. A., Gibbins, J. M.
ORCID: https://orcid.org/0000-0002-0372-5352 and Kennedy, D. R.
(2020)
Zafirlukast is a broad-spectrum thiol isomerase inhibitor that inhibits thrombosis without altering bleeding times.
British Journal of Pharmacology.
ISSN 1476-5381
doi: https://doi.org/10.1111/bph.15291
(In Press)
Sahli, K. A., Flora, G. D., Sasikumar, P., Maghrabi, A. H., Holbrook, L., AlOuda, S. K., Elgheznawy, A., Sage, T., Stainer, A., Adiyaman, R., AboHassan, M., Crescente, M., Kriek, N., Vaiyapuri, S., Bye, A., Unsworth, A., Jones, C., McGuffin, L. and Gibbins, J.
(2020)
Structural, functional and mechanistic insights uncover the fundamental role of orphan connexin 62 in platelets.
Blood.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood.2019004575
Flora, G. D., Sahli, K. A., Sasikumar, P., Holbrook, L.-M., Stainer, A. R., Alouda, S. K., Crescente, M., Sage, T., Unsworth, A. J. and Gibbins, J. M.
(2019)
Non-genomic effects of the Pregnane X Receptor negatively regulate platelet functions, thrombosis and haemostasis.
Scientific Reports, 9 (1).
17210.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-019-53218-x
Stainer, A., Sasikumar, P., Bye, A., Unsworth, A., Holbrook, L., Tindall, M., Lovegrove, J. and Gibbins, J.
(2019)
Quercetin and its methylated metabolites possess anti-thrombotic properties that interact with aspirin to enhance its anti-platelet effects.
TH Open, 3 (3).
e244-e258.
ISSN 2512-9465
doi: https://doi.org/10.1055/s-0039-1694028
Stainer, A. R., Sasikumar, P., Bye, A. P., Unsworth, A. P., Holbrook, L. M., Tindall, M., Lovegrove, J. A. and Gibbins, J. M.
(2019)
The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects.
TH Open, 3 (3).
e244-e258.
ISSN 2512-9465
doi: https://doi.org/10.1055/s-0039-1694028
Sasikumar, P., AlOuda, K. S., Kaiser, W. J., Holbrook, L. M., Kriek, N., Unsworth, A. J., Bye, A. P., Sage, T., Ushioda, R. W., Nagata, K., Farndale, R. W. and Gibbins, J. M.
(2018)
The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and haemostasis.
Journal of Thrombosis and Haemostasis, 16 (5).
pp. 946-959.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.13998
Holbrook, L., Sandhar, G. K., Sasikumar, P., Schenk, M. P., Stainer, A. R., Sahli, K., Flora, G. D., Bicknell, A. B. and Gibbins, J. M.
(2018)
A humanized monoclonal antibody that inhibits platelet-surface ERp72 reveals a role for ERp72 in thrombosis.
Journal of Thrombosis and Haemostasis, 16 (2).
pp. 367-377.
ISSN 1538-7836
doi: https://doi.org/10.1111/jth.13878
Unsworth, A. J., Flora, G. D., Sasikumar, P., Bye, A. P., Sage, T., Kriek, N., Crescente, M. and Gibbins, J. M.
(2017)
RXR ligands negatively regulate thrombosis and hemostasis.
Arteriosclerosis Thrombosis and Vascular Biology, 37 (5).
pp. 812-822.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.117.309207
Moraes, L. A., Unsworth, A. J., Vaiyapuri, S., Ali, M. S., Sasikumar, P., Sage, T., Flora, G. D., Bye, A. P., Kriek, N., Dorchies, E., Molendi-Coste, O., Dombrowicz, D., Staels, B., Bishop-Bailey, D. and Gibbins, J. M.
(2016)
Farnesoid X Receptor and its ligands inhibit the function of platelets.
Arteriosclerosis Thrombosis and Vascular Biology, 36 (12).
pp. 2324-2333.
ISSN 1524-4636
doi: https://doi.org/10.1161/ATVBAHA.116.308093
Jones, C. I., Tucker, K. L., Sasikumar, P., Sage, T., Kaiser, W. J., Moore, C., Emerson, M. and Gibbins, J. M.
(2014)
Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi.
Journal of Thrombosis and Haemostasis, 12 (8).
pp. 1342-1352.
ISSN 1538-7933
doi: https://doi.org/10.1111/jth.12620
Moraes, L. A., Vaiyapuri, S., Sasikumar, P., Ali, M. S., Kriek, N. K., Sage, T. and Gibbins, J. M.
(2013)
Antithrombotic actions of statins involve PECAM-1 signalling.
Blood, 122 (18).
pp. 3188-3196.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2013-04-491845
Kim, K., Hahm, E., Li, J., Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Ushio-Fukai, M., Gibbins, J. M. and Cho, J.
(2013)
Platelet protein disulfide isomerase is required for thrombus formation but not essential for hemostasis in mice.
Blood, 122 (6).
pp. 1052-1061.
ISSN 0006-4971
doi: https://doi.org/10.1182/blood-2013-03-492504
Vaiyapuri, S., Jones, C. I., Sasikumar, P., Moraes, L. A., Munger, S. J., Wright, J. R., Ali, M. S., Sage, T., Kaiser, W. J., Tucker, K. L., Stain, C. J., Bye, A. P., Jones, S., Oviedo-Orta, E., Simon, A. M., Mahaut-Smith, M. P. and Gibbins, J. M.
(2012)
Gap junctions and connexin hemichannels underpin hemostasis and thrombosis.
Circulation, 125 (20).
pp. 2479-2491.
ISSN 0009-7322
doi: https://doi.org/10.1161/CIRCULATIONAHA.112.101246
Holbrook, L.-M., Sasikumar, P., Stanley, R. G., Simmonds, A. D., Bicknell, A. B. and Gibbins, J. M.
(2012)
The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function.
Journal of Thrombosis and Haemostasis, 10 (2).
pp. 278-288.
ISSN 1538-7933
doi: https://doi.org/10.1111/j.1538-7836.2011.04593.x
This list was generated on Tue Jan 26 16:07:03 2021 UTC.