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Items where Author is "Widera, Dr Darius"

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Article

Haque, N., Widera, D. and Abu Kasim, N. H. (2019) Stem cells from human extracted deciduous teeth expanded in foetal bovine and human sera express different paracrine factors after exposure to freshly prepared human serum. Advances in Experimental Medicine and Biology. ISSN 0065-2598 doi: https://doi.org/10.1007/5584_2018_299

Widera, D., Martinez-Aguilar, R. and Cottrell, G. (2019) TLR4 and PAR2 in physiology and pathophysiology of the nervous system: more than just receptor cooperation? Neural Regeneration Research. ISSN 1876-7958 (In Press)

Sheard, J., Ramasamy, T. S. and Widera, D. (2018) From fibroblasts to medicinal signalling cells: a paradigm shift in translational stem cell research. Drug Target Review, 2018 (2). pp. 42-44. ISSN 2059-1349

Zakaria, N., Yusoff, N. M., Zakaria, Z., Widera, D. and Yahaya, B. H. (2018) Inhibition of NF-κB signalling reduces the stemness characteristics of lung cancer stem cells. Frontiers in Oncology, 8. 166. ISSN 2234-943X doi: https://doi.org/10.3389/fonc.2018.00166

Zeuner, M.-T., Didenko, N. N., Humphries, D., Stergiadis, S., Morash, T. M., Patel, K., Grimm, W.-D. and Widera, D. (2018) Isolation and characterisation of neural crest-derived stem cells from adult ovine palatal tissue. Frontiers in Cell and Developmental Biology, 6. 39. ISSN 2296-634X doi: https://doi.org/10.3389/fcell.2018.00039

Krüger, C. L., Zeuner, M.-T., Cottrell, G. S., Widera, D. and Heilemann, M. (2017) Quantitative single-molecule imaging of TLR4 reveals ligand-specific receptor dimerization. Science Signaling, 10 (503). eaan1308. ISSN 1937-9145 doi: https://doi.org/10.1126/scisignal.aan1308

Vallance, T., Zeuner, M.-T., Williams, H., Widera, D. and Vaiyapuri, S. (2017) Toll-like receptor 4 signalling and its impact on platelet function, thrombosis, and haemostasis. Mediators of inflammation, 2017. 9605894. ISSN 0962-9351 doi: https://doi.org/10.1155/2017/9605894

Mellows, B., Mitchell, R., Antonioli, M., Kretz, O., Chamber, D., Zeuner, M.-T., Bernd, D., Musante, L., Durrgah, R., Debacq-Chainiaux, F., Holthofer, H., Joch, B., Ray, S., Widera, D., David, A. L., Huber, T. B., Dengjel, J., De Coppi, P. and Patel, K. (2017) Protein and molecular characterization of a clinically compliant amniotic fluid stem cell derived extracellular vesicle fraction capable of accelerating muscle regeneration through the enhancement of angiogenesis. Stem Cells and Development, 26 (18). pp. 1316-1333. ISSN 1547-3287 doi: https://doi.org/10.1089/scd.2017.0089

Azoidis, I., Metcalfe, J., Reynolds, J., Keeton, S., Hakki, S. S., Sheard, J. and Widera, D. (2017) Three-dimensional cell culture of human mesenchymal stem cells in nanofibrillar cellulose hydrogels. MRS Communications, 7 (3). pp. 458-465. ISSN 2159-6859 doi: https://doi.org/10.1557/mrc.2017.59

Kardia, E., Zakaria, N., Halim, N. S. S. A., Widera, D. and Yahaya, B. H. (2017) The use of mesenchymal stromal cells in treatment of lung disorders. Regenerative Medicine, 12 (2). pp. 2013-2016. ISSN 1746-076X doi: https://doi.org/10.2217/rme-2016-0112

Zeuner, M.-T., Vallance, T., Vaiyapuri, S., Cottrell, G. S. and Widera, D. (2017) Development and characterisation of a novel NF-κB reporter cell line for investigation of neuroinflammation. Mediators of inflammation, 2017. 6209865. ISSN 0962-9351 doi: https://doi.org/10.1155/2017/6209865

Zeuner, M.-T., Krueger, C. L., Volk, K., Bieback, K., Cottrell, G. S., Heilemann, M. and Widera, D. (2016) Biased signalling is an essential feature of TLR4 in glioma cells. Biochimica Et Biophysica Acta (BBA) - Molecular Cell Research, 1863 (12). pp. 3084-3095. ISSN 0167-4889 doi: https://doi.org/10.1016/j.bbamcr.2016.09.016

Müller, J., Greiner, J. F. W., Zeuner, M., Brotzmann, V., Schäfermann, J., Wieters, F., Widera, D., Sudhoff, H., Kaltschmidt, B. and Kaltschmidt, C. (2016) 1,8-cineol potentiates IRF3-mediated antiviral response in human stem cells and an ex vivo model of rhinosinusitis. Clinical Science. ISSN 0143-5221 doi: https://doi.org/10.1042/CS20160218

Widera, D., Klenke, C., Nair, D., Heidbreder, M., Malkusch, S., Sibarita, J.-B., Choquet, D., Kaltschmidt, B., Heilemann, M. and Kaltschmidt, C. (2016) Single-particle tracking uncovers dynamics of glutamate-induced retrograde transport of NF-κB p65 in living neurons. Neurophotonics, 3 (4). 041804. ISSN 2329-4248 doi: https://doi.org/10.1117/1.NPh.3.4.041804

Zeuner, M.-T., Patel, K., Denecke, B., Giebel, B. and Widera, D. (2016) Paracrine effects of TLR4-polarised mesenchymal stromal cells are mediated by extracellular vesicles. Journal of Translational Medicine, 14. 34. ISSN 1479-5876 doi: https://doi.org/10.1186/s12967-016-0794-z

Grimm, W.-D., Giesenhagen, B., Hakki, S., Schau, I., Sirak, S., Sletov, A., Varga, G., Vukovic, M. A. and Widera, D. (2015) Translational research and therapeutic applications of neural crest-derived stem cells in regenerative periodontology. Current Oral Health Reports, 2 (4). pp. 266-274. ISSN 2196-3002 doi: https://doi.org/10.1007/s40496-015-0067-6

Schürmann, M., Frese, N., Beyer, A., Heimann, P., Widera, D., Mönkemöller, V., Huser, T., Barbara, K., Christian, K. and Armin, G. (2015) Helium ion microscopy visualizes lipid nanodomains in mammalian cells. Small, 11 (43). pp. 5781-5789. ISSN 1613-6810 doi: https://doi.org/10.1002/smll.201501540

Zeuner, M., Bieback, K. and Widera, D. (2015) Controversial role of toll-like receptor 4 in adult stem cells. Stem cell reviews and reports, 11 (4). pp. 621-634. ISSN 1558-6804 doi: https://doi.org/10.1007/s12015-015-9589-5

Weber, M., Apostolova, G., Widera, D., Mittelbronn, M., Dechant, G., Kaltschmidt, B. and Rohrer, H. (2015) Alternative generation of CNS neural stem cells and PNS derivatives from neural crest-derived peripheral stem cells. Stem Cells, 33 (2). pp. 574-588. ISSN 1066-5099 doi: https://doi.org/10.1002/stem.1880

Müller, J., Ossig, C., Greiner, J. F. W., Hauser, S., Fauser, M., Widera, D., Kaltschmidt, C., Storch, A. and Kaltschmidt, B. (2015) Intrastriatal transplantation of adult human neural crest-derived stem cells improves functional outcome in parkinsonian rats. Stem cells translational medicine, 4 (1). pp. 31-43. ISSN 2157-6564 doi: https://doi.org/10.5966/sctm.2014-0078

Schürmann, M., Wolff, A., Widera, D., Hauser, S., Heimann, P., Hütten, A., Kaltschmidt, C. and Kaltschmidt, B. (2014) Interaction of adult human neural crest-derived stem cells with a nanoporous titanium surface is sufficient to induce their osteogenic differentiation. Stem Cell Research, 13 (1). pp. 98-110. ISSN 1876-7753 doi: https://doi.org/10.1016/j.scr.2014.04.017

Fricke, F., Malkusch, S., Wangorsch, G., Greiner, J. F., Kaltschmidt, B., Kaltschmidt, C., Widera, D., Dandekar, T. and Heilemann, M. (2014) Quantitative single-molecule localization microscopy combined with rule-based modeling reveals ligand-induced TNF-R1 reorganization toward higher-order oligomers. Histochemistry and cell biology, 142 (1). pp. 91-101. ISSN 1432-119X doi: https://doi.org/10.1007/s00418-014-1195-0

Greiner, J. F. W., Grunwald, L.-M., Müller, J., Sudhoff, H., Widera, D., Kaltschmidt, C. and Kaltschmidt, B. (2014) Culture bag systems for clinical applications of adult human neural crest-derived stem cells. Stem cell research and therapy, 5 (2). 34. ISSN 1757-6512 doi: https://doi.org/10.1186/scrt422

Slotta, C., Müller, J., Tran, L., Hauser, S., Widera, D., Kaltschmidt, B. and Kaltschmidt, C. (2014) An investigation of the specificity of research antibodies against NF-κB-subunit p65. Journal of histochemistry and cytochemistry, 62 (2). pp. 157-161. ISSN 1551-5044 doi: https://doi.org/10.1369/0022155413515484

Widera, D., Müller, J., Imielski, Y., Heimann, P., Kaltschmidt, C. and Kaltschmidt, B. (2014) Methods for the modulation and analysis of NF-κB-dependent adult neurogenesis. Journal of Visualized Experiments, 84. e50870. ISSN 1940-087X doi: https://doi.org/10.3791/50870

Greiner, J. F.-W., Müller, J., Zeuner, M.-T., Hauser, S., Seidel, T., Klenke, C., Grunwald, L.-M., Schomann, T., Widera, D., Sudhoff, H., Kaltschmidt, B. and Kaltschmidt, C. (2013) 1,8-Cineol inhibits nuclear translocation of NF-κB p65 and NF-κB-dependent transcriptional activity. Biochimica Et Biophysica Acta-Molecular Cell Research, 1833 (12). pp. 2866-2878. ISSN 0167-4889 doi: https://doi.org/10.1016/j.bbamcr.2013.07.001

Nguyen, T. D., Widera, D., Greiner, J., Müller, J., Martin, I., Slotta, C., Hauser, S., Kaltschmidt, C. and Kaltschmidt, B. (2013) Prolonged cultivation of hippocampal neural precursor cells shifts their differentiation potential and selects for aneuploid cells. Biological chemistry, 394 (12). pp. 1623-1636. ISSN 1437-4315 doi: https://doi.org/10.1515/hsz-2013-0191

Widera, M., Erkelenz, S., Hillebrand, F., Krikoni, A., Widera, D., Kaisers, W., Deenen, R., Gombert, M., Dellen, R., Pfeiffer, T., Kaltschmidt, B., Münk, C., Bosch, V., Köhrer, K. and Schaal, H. (2013) An intronic G run within HIV-1 intron 2 is critical for splicing regulation of vif mRNA. Journal of Virology, 87 (5). pp. 2707-2720. ISSN 0022-538X doi: https://doi.org/10.1128/JVI.02755-12

Klenke, C., Widera, D., Engelen, T., Müller, J., Noll, T., Niehaus, K., Schmitz, M. L., Kaltschmidt, B. and Kaltschmidt, C. (2013) Hsc70 is a novel interactor of NF-kappaB p65 in living hippocampal neurons. PLoS ONE, 8 (6). e65280. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0065280

Schomann, T., Qunneis, F., Widera, D., Kaltschmidt, C. and Kaltschmidt, B. (2013) Improved method for ex ovo-cultivation of developing chicken embryos for human stem cell xenografts. Stem cells international, 2013. 960958. ISSN 1687-966X doi: https://doi.org/10.1155/2013/960958

Sporbert, A., Cseresnyes, Z., Heidbreder, M., Domaing, P., Hauser, S., Kaltschmidt, B., Kaltschmidt, C., Heilemann, M. and Widera, D. (2013) Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots. PLoS ONE, 8 (5). e64023. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0064023

Martin, I., Nguyen, T. D., Krell, V., Greiner, J. F. W., Müller, J., Hauser, S., Heimann, P. and Widera, D. (2012) Generation of Schwann cell-derived multipotent neurospheres isolated from intact sciatic nerve. Stem cell reviews and reports, 8 (4). pp. 1178-1187. ISSN 1558-6804 doi: https://doi.org/10.1007/s12015-012-9387-2

Chakarov, N., Greiner, J. F. W., Hauser, S., Schuetzmann, D., Krüger, O., Boerner, M. and Widera, D. (2012) Label-free enrichment of avian Leucocytozoon using flow cytometric sorting. Parasitology, 139 (12). pp. 1547-1552. ISSN 0031-1820 doi: https://doi.org/10.1017/S0031182012000972

Heidbreder, M., Zander, C., Malkusch, S., Widera, D., Kaltschmidt, B., Kaltschmidt, C., Nair, D., Choquet, D., Sibarita, J.-B. and Heilemann, M. (2012) TNF-α influences the lateral dynamics of TNF receptor I in living cells. Biochimica Et Biophysica Acta-Molecular Cell Research, 1823 (10). pp. 1984-1989. ISSN 0167-4889 doi: https://doi.org/10.1016/j.bbamcr.2012.06.026

Kaltschmidt, B., Kaltschmidt, C. and Widera, D. (2012) Adult craniofacial stem cells: sources and relation to the neural crest. Stem cell reviews and reports, 8 (3). pp. 658-671. ISSN 1558-6804 doi: https://doi.org/10.1007/s12015-011-9340-9

Hauser, S., Widera, D., Qunneis, F., Müller, J., Zander, C., Greiner, J., Strauss, C., Lüningschrör, P., Heimann, P., Schwarze, H., Ebmeyer, J., Sudhoff, H., Araúzo-Bravo, M. J., Greber, B., Zaehres, H., Schöler, H., Kaltschmidt, C. and Kaltschmidt, B. (2012) Isolation of novel multipotent neural crest-derived stem cells from adult human inferior turbinate. Stem cells and development, 21 (5). pp. 742-756. ISSN 1547-3287 doi: https://doi.org/10.1089/scd.2011.0419

Klenke, C., Janowski, S., Borck, D., Widera, D., Ebmeyer, J., Kalinowski, J., Leichtle, A., Hofestädt, R., Upile, T., Kaltschmidt, C., Kaltschmidt, B. and Sudhoff, H. (2012) Identification of novel cholesteatoma-related gene expression signatures using full-genome microarrays. PLoS ONE, 7 (12). e52718. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0052718

Widera, D., Hauser, S., Kaltschmidt, C. and Kaltschmidt, B. (2012) Origin and regenerative potential of vertebrate mechanoreceptor-associated stem cells. Anatomy research international, 2012. 837626. ISSN 2090-2751 doi: https://doi.org/10.1155/2012/837626

Widera, D., Heimann, P., Zander, C., Imielski, Y., Heidbreder, M., Heilemann, M., Kaltschmidt, C. and Kaltschmidt, B. (2011) Schwann cells can be reprogrammed to multipotency by culture. Stem cells and development, 20 (12). pp. 2053-2064. ISSN 1547-3287 doi: https://doi.org/10.1089/scd.2010.0525

Greiner, J. F. W., Hauser, S., Widera, D., Müller, J., Qunneis, F., Zander, C., Martin, I., Mallah, J., Schuetzmann, D., Prante, C., Schwarze, H., Prohaska, W., Beyer, A., Rott, K., Hütten, A., Gölzhäuser, A., Sudhoff, H., Kaltschmidt, C. and Kaltschmidt, B. (2011) Efficient animal-serum free 3D cultivation method for adult human neural crest-derived stem cell therapeutics. European cells & materials, 22. pp. 403-419. ISSN 1473-2262

Heidbreder, M., Endesfelder, U., van de Linde, S., Hennig, S., Widera, D., Kaltschmidt, B., Kaltschmidt, C. and Heilemann, M. (2010) Subdiffraction fluorescence imaging of biomolecular structure and distributions with quantum dots. Biochimica Et Biophysica Acta-Molecular Cell Research, 1803 (10). pp. 1224-1229. ISSN 0167-4889 doi: https://doi.org/10.1016/j.bbamcr.2010.06.004

Arnold, W. H., Becher, S., Dannan, A., Widera, D., Dittmar, T., Jacob, M., Mannherz, H. G., Dittmar, T., Kaltschmidt, B., Kaltschmidt, C. and Grimm, W.-D. (2010) Morphological characterization of periodontium-derived human stem cells. Annals of Anatomy - Anatomischer Anzeiger, 192 (4). pp. 215-219. ISSN 1618-0402 doi: https://doi.org/10.1016/j.aanat.2010.05.004

Kaus, A., Widera, D., Kassmer, S., Peter, J., Zaenker, K., Kaltschmidt, C. and Kaltschmidt, B. (2010) Neural stem cells adopt tumorigenic properties by constitutively activated NF-kappaB and subsequent VEGF up-regulation. Stem cells and development, 19 (7). pp. 999-1015. ISSN 1547-3287 doi: https://doi.org/10.1089/scd.2009.0416

Widera, D., Zander, C., Heidbreder, M., Kasperek, Y., Noll, T., Seitz, O., Saldamli, B., Sudhoff, H., Sader, R., Kaltschmidt, C. and Kaltschmidt, B. (2009) Adult palatum as a novel source of neural crest-related stem cells. Stem Cells, 27 (8). pp. 1899-1910. ISSN 1066-5099 doi: https://doi.org/10.1002/stem.104

Widera, D., Kaus, A., Kaltschmidt, C. and Kaltschmidt, B. (2008) Neural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours? Journal of Cellular and Molecular Medicine, 12 (2). pp. 459-470. ISSN 1582-4934 doi: https://doi.org/10.1111/j.1582-4934.2007.00208.x

Widera, D., Grimm, W.-D., Moebius, J. M., Mikenberg, I., Piechaczek, C., Gassmann, G., Wolff, N. A., Thévenod, F., Kaltschmidt, C. and Kaltschmidt, B. (2007) Highly efficient neural differentiation of human somatic stem cells, isolated by minimally invasive periodontal surgery. Stem cells and development, 16 (3). pp. 447-60. ISSN 1547-3287 doi: https://doi.org/10.1089/scd.2006.0068

Moebius, J. M., Widera, D., Schmitz, J., Kaltschmidt, C. and Piechaczek, C. (2007) Impact of polysialylated CD56 on natural killer cell cytotoxicity. BMC immunology, 8 (1). 13. ISSN 1471-2172 doi: https://doi.org/10.1186/1471-2172-8-13

Mikenberg, I., Widera, D., Kaus, A., Kaltschmidt, B. and Kaltschmidt, C. (2007) Transcription factor NF-kappaB is transported to the nucleus via cytoplasmic dynein/dynactin motor complex in hippocampal neurons. PLoS ONE, 2 (7). e589. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0000589

Piotrowska, M. J., Widera, D., Kaltschmidt, B., an der Heiden, U. and Kaltschmidt, C. (2006) Mathematical model for NF-kappaB-driven proliferation of adult neural stem cells. Cell proliferation, 39 (6). pp. 441-55. ISSN 0960-7722 doi: https://doi.org/10.1111/j.1365-2184.2006.00403.x

Lindecke, A., Korte, M., Zagrebelsky, M., Horejschi, V., Elvers, M., Widera, D., Prüllage, M., Pfeiffer, J., Kaltschmidt, B. and Kaltschmidt, C. (2006) Long-term depression activates transcription of immediate early transcription factor genes: involvement of serum response factor/Elk-1. The European Journal of Neuroscience, 24 (2). pp. 555-63. ISSN 0953-816X doi: https://doi.org/10.1111/j.1460-9568.2006.04909.x

Mikenberg, I., Widera, D., Kaus, A., Kaltschmidt, B. and Kaltschmidt, C. (2006) TNF-alpha mediated transport of NF-kappaB to the nucleus is independent of the cytoskeleton-based transport system in non-neuronal cells. European Journal of Cell Biology, 85 (6). pp. 529-36. ISSN 0171-9335 doi: https://doi.org/10.1016/j.ejcb.2006.02.007

Widera, D., Mikenberg, I., Kaus, A., Kaltschmidt, C. and Kaltschmidt, B. (2006) Nuclear Factor-kappaB controls the reaggregation of 3D neurosphere cultures in vitro. European cells & materials, 11. pp. 76-85. ISSN 1473-2262

Widera, D., Mikenberg, I., Kaltschmidt, B. and Kaltschmidt, C. (2006) Potential role of NF-kappaB in adult neural stem cells: the underrated steersman? International journal of developmental neuroscience, 24 (2-3). pp. 91-102. ISSN 0736-5748 doi: https://doi.org/10.1016/j.ijdevneu.2005.11.017

Widera, D., Mikenberg, I., Elvers, M., Kaltschmidt, C. and Kaltschmidt, B. (2006) Tumor necrosis factor alpha triggers proliferation of adult neural stem cells via IKK/NF-kappaB signaling. BMC Neuroscience, 7 (1). 64. ISSN 1471-2202 doi: https://doi.org/10.1186/1471-2202-7-64

Kaltschmidt, B., Widera, D. and Kaltschmidt, C. (2005) Signaling via NF-kappaB in the nervous system. Biochimica Et Biophysica Acta-Molecular Cell Research, 1745 (3). pp. 287-99. ISSN 0167-4889 doi: https://doi.org/10.1016/j.bbamcr.2005.05.009

Widera, D., Holtkamp, W., Entschladen, F., Niggemann, B., Zänker, K., Kaltschmidt, B. and Kaltschmidt, C. (2004) MCP-1 induces migration of adult neural stem cells. European Journal of Cell Biology, 83 (8). pp. 381-7. ISSN 0171-9335 doi: https://doi.org/10.1078/0171-9335-00403

Book or Report Section

Neugart, F., Widera, D., Kaltschmidt, B., Kaltschmidt, C. and Heilemann, M. (2012) TNF receptor membrane dynamics studied with fluorescence microscopy and spectroscopy. In: Fluorescent Methods to Study Biological Membranes. Springer, pp. 439-455. doi: https://doi.org/10.1007/4243_2012_60

Widera, D., Kaltschmidt, C. and Kaltschmidt, B. (2009) NF-κB – potential role in adult neural stem cells. In: Encyclopedia of Neuroscience. Springer, pp. 2862-2867. doi: https://doi.org/10.1007/978-3-540-29678-2_3971

Kaltschmidt, B., Mikenberg, I., Widera, D. and Kaltschmidt, C. (2006) The role of NF-κB in brain function. In: Transcription Factors in the Nervous System. Wiley-VCH, pp. 327-352. doi: https://doi.org/10.1002/3527608036.ch16

Book

Gramignoli, R., Sallustio, F., Widera, D. and Raschzok, N., eds. (2019) Tissue repair and regenerative mechanisms by stem/progenitor cells and their secretome. Frontiers in Medicine. Frontiers.

This list was generated on Mon Mar 18 14:50:53 2019 UTC.

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