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Hippocampal adaptations in Mild Cognitive Impairment patients are modulated by bilingual language experiences

Voits, T., Rothman, J., Calabria, M., Robson, H., Aguirre, N., Cattaneo, G., Costumero, V., Hernández, M., Juncadella Puig, M., Marín-Marín, L., Suades, A., Costa, A. and Pliatsikas, C. ORCID: https://orcid.org/0000-0001-7093-1773 (2024) Hippocampal adaptations in Mild Cognitive Impairment patients are modulated by bilingual language experiences. Bilingualism: Language and Cognition, 27 (2). 263 -273. ISSN 1469-1841

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To link to this item DOI: 10.1017/S1366728923000354

Abstract/Summary

Bilingualism has been shown to contribute to increased resilience against cognitive aging. One of the key brain structures linked to memory and dementia symptom onset, the hippocampus, has been observed to adapt in response to bilingual experience, at least in healthy individuals. However, in the context of neurodegenerative pathology, it is yet unclear what role previous bilingual experience might have in terms of sustaining integrity of this structure or related behavioral correlates. The present study adds to the limited cohort of research on the effects of bilingualism on neurocognitive outcomes in Mild Cognitive Impairment (MCI) using structural brain data. We investigate whether bilingual language experience (operationalized as language entropy) results in graded neurocognitive adaptations within a cohort of bilinguals diagnosed with MCI. Results reveal a non-linear effect of bilingual language entropy on hippocampal volume, although it does not predict episodic memory performance, nor age of MCI diagnosis.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary Research Centres (IDRCs) > Centre for Literacy and Multilingualism (CeLM)
Interdisciplinary Research Centres (IDRCs) > Centre for Integrative Neuroscience and Neurodynamics (CINN)
Life Sciences > School of Psychology and Clinical Language Sciences > Department of Clinical Language Sciences
Life Sciences > School of Psychology and Clinical Language Sciences > Language and Cognition
ID Code:111658
Uncontrolled Keywords:bilingualism, Mild Cognitive Impairment, neurodegeneration, aging
Publisher:Cambridge University Press

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