Accessibility navigation

Open hardware for microfluidics: exploiting Raspberry Pi singleboard computer and camera systems for customisable laboratory instrumentation

Sariyer, R. M., Edwards, A. D. ORCID: and Needs, S. H. (2023) Open hardware for microfluidics: exploiting Raspberry Pi singleboard computer and camera systems for customisable laboratory instrumentation. Biosensors, 13 (10). 948. ISSN 2079-6374

Text (Open Access) - Published Version
· Available under License Creative Commons Attribution.
· Please see our End User Agreement before downloading.

[img] Text - Accepted Version
· Restricted to Repository staff only


It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing.

To link to this item DOI: 10.3390/bios13100948


The integration of Raspberry Pi miniature computer systems with microfluidics has revolu-tionized the development of low-cost and customizable analytical systems in life science labor-atories. This review explores the applications of Raspberry Pi in microfluidics, with a focus on imaging, including microscopy and automated image capture. By leveraging the low-cost, flexi-bility and accessibility of Raspberry Pi components, high-resolution imaging and analysis have been achieved in direct mammalian and bacterial cellular imaging and a plethora of image based biochemical and molecular assays, from immunoassays, through microbial growth, to nucleic acid methods such as real-time-qPCR. The control of image capture permitted by Raspberry Pi hard-ware can also be combined with onboard image analysis. Open-source hardware offers an op-portunity to develop complex laboratory instrumentation systems at a fraction of the cost of commercial equipment and importantly, offer an opportunity to completely customise to meet the users’ needs. However, these benefits come with a trade-off: challenges remain for those wishing to incorporate open-source hardware equipment in their own work, including requirements for construction and operator skill, need for good documentation and the availability of rapid pro-totyping such as 3D printing plus other components. These advances in open-source hardware have the potential to improve efficiency, accessibility, and cost-effectiveness of microfluidic-based experiments and applications.

Item Type:Article
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Pharmaceutics Research Group
ID Code:113698


Downloads per month over past year

University Staff: Request a correction | Centaur Editors: Update this record

Page navigation