Markers for nutrition studies: review of criteria for the evaluation of markersde Vries, J., Antoine, J.-M., Burzykowski, T., Chiodini, A., Gibney, M., Kuhnle, G., Méheust, A., Pijls, L. and Rowland, I. (2013) Markers for nutrition studies: review of criteria for the evaluation of markers. European journal of nutrition, 52 (7). pp. 1685-1699. ISSN 1436-6215 Full text not archived in this repository. It is advisable to refer to the publisher's version if you intend to cite from this work. See Guidance on citing. To link to this item DOI: 10.1007/s00394-013-0553-3 Abstract/SummaryThe following criteria were identified as essential elements in the evaluation of markers: (1) the marker has a causal biological link with the endpoint, (2) there is a significant association between marker and endpoint in the target population, (3) marker changes consistently with the endpoint, e.g., in response to an intervention, and (4) change in the marker explains a substantial proportion of the change in the endpoint in response to the intervention.
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