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Novel probiotics and prebiotics : road to the market

Kumar, H., Salminen, S., Verhagen, H., Rowland, I., Heimbach, J., Bañares, S., Young, T., Nomoto, K. and Lalonde, M. (2015) Novel probiotics and prebiotics : road to the market. Current Opinion in Biotechnology, 32. pp. 99-103. ISSN 0958-1669

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To link to this item DOI: 10.1016/j.copbio.2014.11.021


Novel probiotics and prebiotics designed to manipulate the gut microbiota for improving health outcomes are in demand as the importance of the gut microbiota in human health is revealed. The regulations governing introduction of novel probiotics and prebiotics vary by geographical region. Novel foods and foods with health claims fall under specific regulations in several countries. The paper reviews the main requirements of the regulations in the EU, USA, Canada and Japan. We propose a number of areas that need to be addressed in any safety assessment of novel probiotics and prebiotics. These include publication of the genomic sequence, antibiotic resistance profiling, selection of appropriate in vivo model, toxicological studies (including toxin production) and definition of target population.

Item Type:Article
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
ID Code:38692

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