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The importance of loop length on the stability of i-motif structures

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Gurung, S. P., Schwarz, C., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X (2015) The importance of loop length on the stability of i-motif structures. Chemical Communications, 51 (26). pp. 5630-5632. ISSN 1359-7345

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To link to this item DOI: 10.1039/C4CC07279K

Abstract/Summary

Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.

Item Type:Article
Refereed:Yes
Divisions:Life Sciences > School of Chemistry, Food and Pharmacy > Department of Chemistry
Interdisciplinary centres and themes > Chemical Analysis Facility (CAF) > Optical Spectroscopy (CAF)
Life Sciences > School of Chemistry, Food and Pharmacy > School of Pharmacy > Medicinal Chemistry Research Group
ID Code:39189
Publisher:The Royal Society of Chemistry
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