Number of items at this level: 125.
2024
Mitry, M. M.A., Dallas, M. ORCID: https://orcid.org/0000-0002-5190-0522, Boateng, S. Y., Greco, F. and Osborn, H. M.I. ORCID: https://orcid.org/0000-0002-0683-0457
(2024)
Selective activation of prodrugs in breast cancer using metabolic glycoengineering and the tetrazine ligation bioorthogonal reaction.
Bioorganic Chemistry, 147.
107304.
ISSN 0045-2068
doi: https://doi.org/10.1016/j.bioorg.2024.107304
Poshtkohi, A., Wade, J., McDaid, L., Liu, J., Dallas, M. L. ORCID: https://orcid.org/0000-0002-5190-0522 and Bithell, A.
(2024)
Mathematical modeling of PI3K/Akt pathway in microglia.
Neural Computation, 36 (4).
pp. 645-676.
ISSN 1530-888X
doi: https://doi.org/10.1162/neco_a_01643
2023
Cheeseman, J., Badia, C., Elgood-Hunt, G., Gardner, R. A., Trinh, D. N., Monopoli, M. P., Kuhnle, G. ORCID: https://orcid.org/0000-0002-8081-8931, Spencer, D. I. R. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2023)
Elevated concentrations of Neu5Ac and Neu5,9Ac2 in human plasma: potential biomarkers of cardiovascular disease.
Glycoconjugate Journal, 40 (6).
pp. 645-654.
ISSN 1573-4986
doi: https://doi.org/10.1007/s10719-023-10138-3
Khater, M., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Greco, F. and Osborn, H. ORCID: https://orcid.org/0000-0002-0683-0457
(2023)
Anticancer evaluation of new organometallic ruthenium(II) flavone complexes.
Medicinal Chemistry, 14 (2).
pp. 253-267.
ISSN 2632-8682
doi: https://doi.org/10.1039/D2MD00304J
Kramer, H.B.R. and Allman, S. A.
(2023)
Sugar coating autophagy: exploring the links between the inhibition of NGLY1 (N-glycanase 1) and autophagy induction.
Autophagy Reports, 2 (1).
2166324.
ISSN 2769-4127
doi: https://doi.org/10.1080/27694127.2023.2166324
Mitry, M. M. A., Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2023)
In vivo applications of bioorthogonal reactions- chemistry and targeting mechanisms.
Chemistry - A European Journal, 29 (20).
e202203942.
ISSN 0947-6539
doi: https://doi.org/10.1002/chem.202203942
Mitry, M. M.A., Boateng, S. Y., Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2023)
Bioorthogonal activation of prodrugs, for the potential treatment of breast cancer, using the Staudinger reaction.
RSC Medicinal Chemistry, 14 (8).
pp. 1537-1548.
ISSN 2632-8682
doi: https://doi.org/10.1039/D3MD00137G
Pozza, M. D., Mesdom, P., Abdullrahman, A., Prieto Otoya, T. D., Arnoux, P., Frochot, C. ORCID: https://orcid.org/0000-0002-7659-3864, Niogret, G., Saubaméa, B., Burckel, P., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Hollenstein, M. ORCID: https://orcid.org/0000-0003-0263-9206, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Gasser, G. ORCID: https://orcid.org/0000-0002-4244-5097
(2023)
Increasing the π-expansive ligands in ruthenium(II) polypyridyl complexes: synthesis, characterization, and biological evaluation for photodynamic therapy applications.
Inorganic Chemistry, 62 (45).
pp. 18510-18523.
ISSN 1520-510X
doi: https://doi.org/10.1021/acs.inorgchem.3c02606
2022
Albadawi, D. A. I., Ravishankar, D., Vallance, T. M., Patel, K., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517
(2022)
Impacts of commonly used edible plants on the modulation of platelet function.
International Journal of Molecular Sciences, 23 (2).
605.
ISSN 1422-0067
doi: https://doi.org/10.3390/ijms23020605
Allman, S., Cordy, J., Hall, J. ORCID: https://orcid.org/0000-0003-3716-4378, Kleanthous, V. and Lander, L.
(2022)
Exploring the perception of additional information content in 360° 3D VR video for teaching and learning.
Virtual Worlds, 1 (1).
pp. 1-17.
ISSN 2813-2084
doi: https://doi.org/10.3390/virtualworlds1010001
Baker, Y. R., Thorpe, C., Chen, J., Poller, L. M., Cox, L., Kumar, P., Lim, W. F., Lie, L., McClorey, G., Epple, S., Singleton, D., McDonough, M. A., Hardwick, J. S., Christensen, K. E., Wood, M. J. A., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, El-Sagheer, A. H. and Brown, T.
(2022)
An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.
Nature Communications, 13.
pp. 1-13.
ISSN 2041-1723
doi: https://doi.org/10.1038/s41467-022-31636-2
Cheeseman, J., Badia, C., Thomson, R. I., Kuhnle, G. ORCID: https://orcid.org/0000-0002-8081-8931, Gardner, R. A., Spencer, D. I. R. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2022)
Quantitative standards of 4-O acetyl and 9-O acetyl N-acetyl neuraminic acid for the analysis of plasma and serum.
ChemBioChem, 23 (5).
e202100662.
ISSN 1439-7633
doi: https://doi.org/10.1002/cbic.202100662
Dalla Pozza, M., Abdullrahman, A., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Gasser, G. and Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378
(2022)
Three’s a crowd – stabilisation, structure, and applications of DNA triplexes.
Chemical Science (35).
pp. 10193-10215.
ISSN 2041-6539
doi: https://doi.org/10.1039/d2sc01793h
Hutchins, M., Bovill, R. A., Stephens, P. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2022)
Glycosides of nadifloxacin—synthesis and antibacterial
activities against methicillin-resistant Staphylococcus aureus.
Molecules, 27 (5).
1504.
ISSN 1420-3049
doi: https://doi.org/10.3390/molecules27051504
Khater, M., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Boateng, S. Y., Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2022)
Halogenated flavonoid derivatives display antiangiogenic activity.
Molecules, 27 (15).
4757.
ISSN 1420-3049
doi: https://doi.org/10.3390/molecules27154757
McQuaid, K. T. ORCID: https://orcid.org/0000-0002-3222-5584, Takahashi, S., Baumgaertner, L., Cardin, D. J., Paterson, N. G., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sugimoto, N. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995
(2022)
Ruthenium polypyridyl complex bound to a unimolecular chair-form G-quadruplex.
Journal of the American Chemical Society, 144 (13).
pp. 5956-5964.
ISSN 0002-7863
doi: https://doi.org/10.1021/jacs.2c00178
Ridzuan, N., Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X and Yahaya, B. H.
(2022)
Isolation and characterization of extracellular vesicles derived from human umbilical cord mesenchymal stem cells.
In: Kannan, N. and Beer, P. (eds.)
Stem Cell Assays.
Methods in Molecular Biology, 2429 (2429).
Springer, pp. 271-280.
ISBN 9781071619797
doi: https://doi.org/10.1007/978-1-0716-1979-7_18
(ISSN 1940-6029)
Skurikhin, E. G., Pershina, O. ORCID: https://orcid.org/0000-0002-0468-0272, Ermakova, N., Pakhomova, A. ORCID: https://orcid.org/0000-0003-0725-1323, Widera, D. ORCID: https://orcid.org/0000-0003-1686-130X, Zhukova, M. ORCID: https://orcid.org/0000-0002-8146-2279, Pan, E. ORCID: https://orcid.org/0000-0002-2163-7647, Sandrikina, L., Kogai, L., Kushlinskii, N., Morozov, S. G., Kubatiev, A. and Dygai, A.
(2022)
Reprogrammed CD8+ T-lymphocytes isolated from bone marrow have anticancer potential in lung cancer.
Biomedicines, 10 (6).
1450.
ISSN 2227-9059
doi: https://doi.org/10.3390/biomedicines10061450
Trinh, D. N., Radlinskaite, M., Cheeseman, J., Kuhnle, G. ORCID: https://orcid.org/0000-0002-8081-8931, Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457, Meleady, P., Spencer, D. I. R. and Monopoli, M. P.
(2022)
Biomolecular corona stability in association with plasma
cholesterol level.
Nanomaterials, 12 (15).
2661.
ISSN 2079-4991
doi: https://doi.org/10.3390/nano12152661
2021
Babra, T., Warriner, C., Bazin, N., Hayes, W. ORCID: https://orcid.org/0000-0003-0047-2991 and Greenland, B.
(2021)
A fluoride degradable crosslinker for debond-on-demand polyurethane based crosslinked adhesives.
Materials Today Communications, 26.
101777.
ISSN 2352-4928
doi: https://doi.org/10.1016/j.mtcomm.2020.101777
Cheeseman, J., Kuhnle, G. ORCID: https://orcid.org/0000-0002-8081-8931, Stafford, G., Gardner, R., Spencer, D. and Osborn, H. ORCID: https://orcid.org/0000-0002-0683-0457
(2021)
Sialic acid as a potential biomarker for cardiovascular disease, diabetes and cancer.
Biomarkers in Medicine, 15 (11).
pp. 911-928.
ISSN 1752-0363
doi: https://doi.org/10.2217/bmm-2020-0776
Cheeseman, J., Kuhnle, G. ORCID: https://orcid.org/0000-0002-8081-8931, Spencer, D. I.R. and Osborn, H. ORCID: https://orcid.org/0000-0002-0683-0457
(2021)
Assays for the identification and quantification of sialic acids: challenges, opportunities and future perspectives.
Bioorganic & Medicinal Chemistry, 30.
115882.
ISSN 0968-0896
doi: https://doi.org/10.1016/j.bmc.2020.115882
Dawood, D. H., Srour, A. M., Saleh, D. O., Huff, K. J., Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2021)
New pyridine and chromene scaffolds as potent vasorelaxant and anticancer agents.
RSC Advances, 11.
pp. 29441-29452.
ISSN 2046-2069
doi: https://doi.org/10.1039/D1RA04758B
Manzoni, C. and Ferrari, R.
(2021)
Mendelian and sporadic FTD: disease risk and avenues from genetics to disease pathways through in silico modelling.
In: Ghetti, B., Buratti, E., Boeve, B. and Rademakers, R. (eds.)
Frontotemporal Dementias.
Advances in Experimental Medicine and Biology, 1281.
Springer, pp. 283-296.
ISBN 9783030511395
doi: https://doi.org/10.1007/978-3-030-51140-1_17
2020
Baptista, F. R., Devereux, S. J., Gurung, S. P., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Sazanovich, I. V., Towrie, M., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Kelly, J. M. and Quinn, S. J.
(2020)
The influence of loops on the binding of the [Ru(phen)2dppz]2+ light-switch compound to i-motif DNA structures revealed by time-resolved spectroscopy.
Chemical Communications, 56 (67).
pp. 9703-9706.
ISSN 1359-7345
doi: https://doi.org/10.1039/D0CC03702H
Council, C. E., Kilpin, K. J., Gusthart, J. S. ORCID: https://orcid.org/0000-0002-1529-9493, Allman, S. A., Linclau, B. and Lee, S. S.
(2020)
Enzymatic glycosylation involving fluorinated carbohydrates.
Organic & Biomolecular Chemistry, 18 (18).
pp. 3423-3451.
ISSN 1477-0520
doi: https://doi.org/10.1039/D0OB00436G
Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378 and Allman, S. A.
(2020)
Blending virtual reality with traditional approaches to encourage engagement with core chemistry concepts relevant to an undergraduate pharmacy curriculum.
Pharmacy Education, 20 (1).
pp. 365-374.
ISSN 1477-2701
doi: https://doi.org/10.46542/pe.2020.201.365374
Khater, M., Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2020)
Antiangiogenic activity of flavonoids: a systematic review and meta-analysis.
Molecules, 25 (20).
4712.
ISSN 1420-3049
doi: https://doi.org/10.3390/molecules25204712
Natfji, A. A. ORCID: https://orcid.org/0000-0002-6168-4632, Nikitin, D. O., Semina, I. I., Moustafine, R. I., Khutoryanskiy, V. V. ORCID: https://orcid.org/0000-0002-7221-2630, Lin, H., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Greco, F.
(2020)
Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects.
Journal of Controlled Release, 322.
pp. 227-235.
ISSN 0168-3659
doi: https://doi.org/10.1016/j.jconrel.2020.02.037
Tomkins, J. E.
(2020)
Defining the Proximal Interactome of Death-Associated Protein Kinase 1.
PhD thesis, University of Reading.
doi: https://doi.org/10.48683/1926.00104248
2019
Conlon, P. F., Eguaogie, O., Wilson, J., Sweet, J. S. T., Steinhögl, J., Englert, K., Hancox, O. G. A., Law, C. J., Allman, S. A., Tucker, J. H. R., Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378 and Vyle, J. S.
(2019)
Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography.
Chemical Science, 10 (47).
pp. 10948-10957.
ISSN 1478-6524
doi: https://doi.org/10.1039/C9SC04098F
Howse, G. L., Bovill, R. A., Stephens, P. J. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2019)
Synthesis and antibacterial profiles of targeted triclosan derivatives.
European Journal of Medicinal Chemistry, 162.
pp. 51-58.
ISSN 0223-5234
doi: https://doi.org/10.1016/j.ejmech.2018.10.053
Khater, M., Ravishankar, D., Greco, F. and Osborn, H. ORCID: https://orcid.org/0000-0002-0683-0457
(2019)
Metal complexes of flavonoids: their synthesis, characterization, and enhanced anti-oxidant and anti-cancer activities.
Future Medicinal Chemistry, 11 (21).
ISSN 1756-8927
doi: https://doi.org/10.4155/fmc-2019-0237
McQuaid, K. ORCID: https://orcid.org/0000-0002-3222-5584, Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Baumgaertner, L., Cardin, D. J. and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995
(2019)
Three thymine/adenine binding modes of the ruthenium complex Λ-[Ru (TAP)2(dppz)]2+ to the G-quadruplex forming sequence d(TAGGGTT) shown by X-ray crystallography.
Chemical Communications, 55.
pp. 9116-9119.
ISSN 1359-7345
doi: https://doi.org/10.1039/C9CC04316K
McQuaid, K., Abell, H., Gurung, S. P., Allan, D. R., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378
(2019)
Structural studies reveal the enantiospecific recognition of a DNA G-quadruplex by a ruthenium polypyridyl complex.
Angewandte Chemie International Edition, 58 (29).
pp. 9881-9885.
ISSN 1433-7851
doi: https://doi.org/10.1002/anie.201814502
Strohfeldt, K.
(2019)
The power of the virtual client – using problem-based
learning as a tool for integration in a
pharmaceutical sciences laboratory course.
Higher Education Pedagogies, 4 (1).
pp. 462-475.
ISSN 2375-2696
doi: https://doi.org/10.1080/23752696.2019.1686647
Vallance, T. M., Ravishankar, D., Albadawi, D. A. I., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517
(2019)
Synthetic flavonoids as novel modulators of platelet function and thrombosis.
International Journal of Molecular Sciences, 20 (12).
e3106.
ISSN 1422-0067
doi: https://doi.org/10.3390/ijms20123106
2018
Bootman, M. D., Allman, S., Rietdorf, K. and Bultynck, G.
(2018)
Deleterious effects of calcium indicators within cells: an inconvenient truth.
Cell Calcium, 73.
pp. 82-87.
ISSN 0143-4160
doi: https://doi.org/10.1016/j.ceca.2018.04.005
Brown, G. D., Bauer, J., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Kuemmerle, R.
(2018)
A solution NMR approach to determine the chemical structures of carbohydrates using the hydroxyl groups as starting points.
ACS Omega, 3 (12).
pp. 17957-17975.
ISSN 2470-1343
doi: https://doi.org/10.1021/acsomega.8b02136
Murray, C. A., Zhu, Z., Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Colquhoun, H. M. and Greenland, B. W.
(2018)
Quadruple stacking of macrocyclic viologen radical-cations.
Supramolecular Chemistry, 30 (9).
pp. 751-757.
ISSN 1061-0278
doi: https://doi.org/10.1080/10610278.2017.1375113
Parker, M. P., Murray, C. A., Hart, L. R., Greenland, B. W., Hayes, W. ORCID: https://orcid.org/0000-0003-0047-2991, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995 and Colquhoun, H. M.
(2018)
Mutual complexation between π-π stacked molecular tweezers.
Crystal Growth and Design, 18 (1).
pp. 386-392.
ISSN 1528-7505
doi: https://doi.org/10.1021/acs.cgd.7b01376
Stachulski, A. V., Santoro, M. G., Piacentini, S., Belardo, G., La Frazia, S., Pidathala, C., Row, E. C., Berry, N. G., Iqbal, M., Allman, S. A., Semple, J.E., Eklov, B. M., O'Neill, P. M. and Rossignol, J.-F.
(2018)
Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus.
Future Medicinal Chemistry, 10 (8).
pp. 851-862.
ISSN 1756-8927
doi: https://doi.org/10.4155/fmc-2017-0217
2017
Hall, J. P. ORCID: https://orcid.org/0000-0003-3716-4378, Gurung, S. P., Henle, J., Poidl, P., Andersson, J., Lincoln, P., Winter, G., Sorensen, T., Cardin, D. J., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995
(2017)
Guanine can direct binding specificity of Ru-dppz complexes to DNA through steric effects.
Chemistry: A European Journal, 23 (21).
pp. 4981-4985.
ISSN 0947-6539
doi: https://doi.org/10.1002/chem.201605508
Hart, L. R., Hayes, W. ORCID: https://orcid.org/0000-0003-0047-2991 and Greenland, B. W.
(2017)
Polymeric materials based on NDI and its congeners.
In: Pantos, G. D. (ed.)
Naphthalenediimide and its Congeners: From Molecules to Materials.
Monographs in Supramolecular Chemistry.
Royal Society of Chemistry, London, pp. 167-217.
ISBN 9781849739221
doi: https://doi.org/10.1039/9781782621386-00167
Natfji, A. A., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Greco, F.
(2017)
Feasibility of polymer-drug conjugates for non-cancer applications.
Current Opinion in Colloid & Interface Science, 31.
pp. 51-66.
ISSN 1359-0294
doi: https://doi.org/10.1016/j.cocis.2017.07.004
Natfji, A. A., Ravishankar, D., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Greco, F.
(2017)
Parameters affecting the enhanced permeability and retention effect: the need for patient selection.
Journal of Pharmaceutical Sciences, 106 (11).
pp. 3179-3187.
ISSN 0022-3549
doi: https://doi.org/10.1016/j.xphs.2017.06.019
Ravishankar, D., Salamah, M., Attina, A., Pothi, R., Vallance, T. M., Javed, M., Williams, H. F., Alzahrani, E. M. S., Kabova, E., Vaiyapuri, R., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155, Gibbins, J. ORCID: https://orcid.org/0000-0002-0372-5352, Strohfeldt, K., Greco, F., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Vaiyapuri, S. ORCID: https://orcid.org/0000-0002-6006-6517
(2017)
Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy.
Scientific Reports, 7.
5738.
ISSN 2045-2322
doi: https://doi.org/10.1038/s41598-017-05936-3
Takahashi, S., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X and Sugimoto, N.
(2017)
Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America, 114 (36).
pp. 9605-9610.
ISSN 0027-8424
doi: https://doi.org/10.1073/pnas.1704258114
Thomson, R. I., Gardner, R. A., Strohfeldt, K., Fernandes, D. L., Stafford, G. P., Spencer, D. I. R. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2017)
Analysis of three epoetin alpha products by LC and LC-MS indicates differences in glycosylation critical quality attributes, including sialic acid content.
Analytical Chemistry, 89 (12).
pp. 6455-6462.
ISSN 0003-2700
doi: https://doi.org/10.1021/acs.analchem.7b00353
2016
Al-Ani, W., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155 and Cobb, A. J. A.
(2016)
Asymmetric organocatalytic synthesis of cyclopentane γ-nitroketones.
Synlett, 27 (1).
pp. 17-20.
ISSN 0936-5214
doi: https://doi.org/10.1055/s-0035-1560504
Bovill, R., Evans, P. G., Howse, G. L. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2016)
Synthesis and biological analysis of novel glycoside derivatives of L-AEP, as targeted antibacterial agents.
Bioorganic & Medicinal Chemistry Letters, 26 (15).
pp. 3774-3779.
ISSN 0960-894X
doi: https://doi.org/10.1016/j.bmcl.2016.05.052
Bryant, L. A., Fanelli, R. and Cobb, A. J. A.
(2016)
Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts.
Beilstein Journal of Organic Chemistry, 12.
pp. 429-443.
ISSN 1860-5397
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Organic and Biomolecular Chemistry, 14 (3).
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Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes.
Nucleic Acids Research, 44 (19).
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ISSN 1362-4962
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Heath, F., Newman, A., Clementi, C., Pasut, G., Lin, H., Stephens, G. J. ORCID: https://orcid.org/0000-0002-8966-4238, Whalley, B. J., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Greco, F.
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A novel PEG–haloperidol conjugate with a non-degradable linker shows the feasibility of using polymer–drug conjugates in a non-prodrug fashion.
Polymer Chemistry, 7 (47).
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ISSN 1759-9954
doi: https://doi.org/10.1039/c6py01418f
Keane, P. M., Baptista, F. R., Gurung, S. P., Devereux, S. J., Sazanovich, I. V., Towrie, M., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Cardin, C. J. ORCID: https://orcid.org/0000-0002-2556-9995, Kelly, J. M. and Quinn, S. J.
(2016)
Long-lived excited-state dynamics of i-motif structures probed by time-resolved infrared spectroscopy.
ChemPhysChem, 17 (9).
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ISSN 1439-7641
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Parshotam, J. P., Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Bovill, R. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
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An efficient and rapid microwave-assisted synthesis of 1-acetyl-1H-indol-3-YL acetates.
Current Microwave Chemistry, 3 (3).
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ISSN 2213-3364
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Ravishankar, D., Corona, G., Hogan, S. M., Spencer, J. P. E. ORCID: https://orcid.org/0000-0003-2931-7274, Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
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Thioflavones as novel neuroprotective agents.
Bioorganic & Medicinal Chemistry, 24 (21).
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Ravishankar, D., Watson, K. A. ORCID: https://orcid.org/0000-0002-9987-8539, Greco, F. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
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Novel synthesised flavone derivatives provide significant insight into the structural features required for enhanced anti-proliferative activity.
RSC Advances, 6 (69).
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Sinclair, F., Chen, L., Greenland, B. W. and Shaver, M. P.
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Installing multiple functional groups on biodegradable polyesters
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2015
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Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to d3-amino acids.
Chemical Communications, 51 (70).
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Sialic acids in biological and therapeutic processes: opportunities and challenges.
Future Medicinal Chemistry, 7 (16).
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Targeted activation of toll-like receptors: conjugation of a toll-like receptor 7 agonist to a monoclonal antibody maintains antigen binding and specificity.
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Donor-acceptor π−π stacking interactions: from small molecule complexes to healable supramolecular polymer networks.
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Supramolecular polymer networks and gels.
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Chemical Communications, 51 (26).
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Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy.
Nature Chemistry, 7.
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Stabilization of the i-motif structure by the intra-strand cross-link formation.
Bioorganic & Medicinal Chemistry Letters, 25 (16).
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MacDonald, J. P., Parker, M. P., Greenland, B. W., Hermida-Merino, D., Hamley, I. W. ORCID: https://orcid.org/0000-0002-4549-0926 and Shaver, M. P.
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Tuning thermal properties and microphase
separation in aliphatic polyester ABA copolymers.
Polymer Chemistry, 6 (9).
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Olorunniji, F. J., McPherson, A. L., Pavlou, H. J., McIlwraith, M. J., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X, Cosstick, R. and Stark, W. M.
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Nicked-site substrates for a serine recombinase reveal enzyme–DNA communications and an essential tethering role of covalent enzyme–DNA linkages.
Nucleic Acids Research, 43 (12).
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European Journal of Medicinal Chemistry, 97.
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Synthesis and antiviral properties of spirocyclic [1,2,3]-triazolooxazine nucleosides.
Chemistry- A European Journal, 20 (37).
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Multivalency in healable supramolecular polymers:
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Fragmentation of negative ions from N-linked carbohydrates: Part 6. Glycans containing oneN-acetylglucosamine in the core.
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Polymers, 6 (8).
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Robust and operationally simple synthesis of Poly(bis(2,2,2-
trifluoroethoxy) phosphazene) with controlled molecular weight, low PDI, and high conversion.
ACS Macro Letters, 3.
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Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.
Cellular and Molecular Life Sciences, 70 (15).
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Urea organogelators: synthesis and properties.
Macromolecular Symposia, 329 (1).
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Lightly branched comb polyesters: application in fast drying solvent-borne coating formulations.
Reactive & Functional Polymers, 73 (4).
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Mutual binding of polymer end-groups by complementary π–π-stacking: a molecular “Roman Handshake”.
Chemical Communications, 49 (5).
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Jarvis, A. N., McClaren, A. B., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Sweeney, J.
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Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines.
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Pairwise assembly of organopalladium(II) units with cyanurato(3-) and trithiocyanurato(3-) ligands: formation of chiral Pd12, Pd10 and Pd9 cage-molecules.
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Organocatalytic domino reaction of cyanosulfones: access to complex cyclohexane systems with quaternary carbon centers.
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Flavonoids as prospective compounds for anti-cancer therapy.
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I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes.
Chemical Communication, 48 (87).
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Mild and rapid method for the generation of ortho-(naphtho)-quinone methide intermediates.
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Bioorganic & Medicinal Chemistry, 19 (18).
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ISSN 0008-6215
doi: https://doi.org/10.1016/j.carres.2009.08.034
Kolstoe, S. E., Mangione, P. P., Bellotti, V., Taylor, G. W., Tennent, G. A., Deroo, S., Morrison, A. J., Cobb, A. J. A., Coyne, A., McCammon, M. G., Warner, T. D., Mitchell, J., Gill, R., Smith, M. D., Ley, S. V., Robinson, S. P. and Pepys, M. B.
(2010)
Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Proceedings of the National Academy of Sciences of the United States of America, 107 (47).
pp. 20483-20488.
ISSN 0027-8424
doi: https://doi.org/10.1073/pnas.1008255107
Nodes, W. J., Shankland, K. ORCID: https://orcid.org/0000-0001-6566-0155, Rajkumar, S. and Cobb, A. J. A.
(2010)
Asymmetric phase-transfer-catalyzed synthesis of five-membered cyclic gamma-Amino acid precursors.
Synlett, 2010 (20).
pp. 3011-3014.
ISSN 1437-2096
doi: https://doi.org/10.1055/s-0030-1259050
Strohfeldt, K. and Grant, D. T.
(2010)
A model for self-directed problem-based learning for renal therapeutics.
American Journal of Pharmaceutical Education , 74 (9).
Article 173.
2009
Allman, S. A., Jensen, H. H., Vijayakrishnan, B., Garnett, J. A., Leon, E., Liu, Y., Anthony, D. C., Sibson, N. R., Feizi, T., Matthews, S. and Davis, B. G.
(2009)
Potent fluoro-oligosaccharide probes of adhesion in Toxoplasmosis.
ChemBioChem, 10 (15).
pp. 2522-2529.
ISSN 1439-7633
doi: https://doi.org/10.1002/cbic.200900425
Garnett, J. A., Liu, Y., Leon, E., Allman, S. A., Friedrich, N., Saouros, S., Curry, S., Soldati-Favre, D., Davis, B. G., Feizi, T. and Matthews, S.
(2009)
Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii.
Protein Science, 18 (9).
pp. 1935-1947.
ISSN 0961-8368
doi: https://doi.org/10.1002/pro.204
Jawaid, S., Khan, T. H., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Williams, N. O. A.
(2009)
Tyrosinase activated melanoma prodrugs.
Anti-cancer agents in medicinal chemistry, 9 (7).
pp. 717-727.
ISSN 1871-5206
Nodes, W., Nutt, D. R., Chippindale, A. M. ORCID: https://orcid.org/0000-0002-5918-8701 and Cobb, A. J. A.
(2009)
Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters.
Journal of the American Chemical Society, 131 (44).
pp. 16016-16017.
ISSN 0002-7863
doi: https://doi.org/10.1021/ja9070915
Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457 and Turkson, A.
(2009)
Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside.
Tetrahedron Asymmetry, 20 (18).
pp. 2162-2166.
ISSN 0957-4166
doi: https://doi.org/10.1016/j.tetasy.2009.08.004
Vessieres, A., Plamont, M.-A., Cabestaing, C., Claffey, J., Dieckmann, S., Hogan, M., Mueller-Bunz, H., Strohfeldt, K. A. and Tacke, M.
(2009)
Proliferative and anti-proliferative effects of titanium- and iron-based metallocene anti-cancer drugs.
Journal of Organometallic Chemistry , 694 (6).
pp. 874-879.
ISSN 0022-328X
doi: https://doi.org/10.1016/j.jorganchem.2008.11.071
2008
Baksh, M. F. ORCID: https://orcid.org/0000-0003-3107-8815 and Kelly, P.
(2008)
Statistical methods for examining genetic influences of resistance to anti-epileptic drugs.
Expert Review of Clinical Pharmacology, 1 (1).
pp. 137-144.
ISSN 1751-2433
doi: https://doi.org/10.1586/17512433.1.1.137
Bonjoch, J., Drew, M. G.B., Gonzalez, A., Greco, F., Jawaid, S., Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457, Williams, N. A.O. and Yaqoob, P. ORCID: https://orcid.org/0000-0002-6716-7599
(2008)
Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma.
Journal of Medicinal Chemistry, 51 (20).
pp. 6604-6608.
ISSN 0022-2623
doi: https://doi.org/10.1021/jm8007745
Ellis, D., Norman, S. E. and Osborn, H. M. I. ORCID: https://orcid.org/0000-0002-0683-0457
(2008)
Synthesis of S-linked carbohydrate analogues via a Ferrier reaction.
Tetrahedron, 64 (12).
pp. 2832-2854.
ISSN 0040-4020
doi: https://doi.org/10.1016/j.tet.2008.01.042
Strohfeldt, K. A. and Tacke, M.
(2008)
Bioorganometallic fulvene-derived titanocene anti-cancer drugs.
Chemical Society Reviews, 37 (6).
pp. 1174-1187.
ISSN 0306-0012
doi: https://doi.org/10.1039/b707310k
2007
Campo, V. L., Carvalho, I., Allman, S., Davis, B. G. and Field, R. A.
(2007)
Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins.
Organic & Biomolecular Chemistry, 5 (16).
pp. 2645-2657.
ISSN 1477-0520
doi: https://doi.org/10.1039/b707772f
Gaynor, J. W., Brazier, J. ORCID: https://orcid.org/0000-0002-4952-584X and Cosstick, R.
(2007)
Synthesis of 3 '-S-phosphorothiolate oligonucleotides for their potential use in RNA interference.
Nucleosides Nucleotides & Nucleic Acids, 26 (6-7).
pp. 709-712.
ISSN 1525-7770
doi: https://doi.org/10.1080/15257770701490753
2005
Brazier, J. A. ORCID: https://orcid.org/0000-0002-4952-584X, Shibata, T., Townsley, J., Taylor, B. F., Frary, E., Williams, N. H. and Williams, D. M.
(2005)
Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation.
Nucleic Acids Research, 33 (4).
pp. 1362-1371.
ISSN 1362-4962
doi: https://doi.org/10.1093/nar/gki254
This list was generated on Thu Nov 21 13:58:36 2024 UTC.