Items where Division is "Medicinal Chemistry Research Group"
Number of items at this level: 123. 2023
Cheeseman, Jack, Badia, Concepcion, Elgood-Hunt, Georgia, Gardner, Richard, Trinh, Duong, Monopoli, Marco, Kuhnle, Gunter Khater, Mai, Brazier, John, Greco, Francesca and Osborn, Helen (2023) Anticancer evaluation of new organometallic ruthenium(II) flavone complexes. Medicinal Chemistry, 14 (2). pp. 253-267. ISSN 2632-8682 doi: https://doi.org/10.1039/D2MD00304J Kramer, H.B.R. and Allman, Sarah Ann (2023) Sugar coating autophagy: exploring the links between the inhibition of NGLY1 (N-glycanase 1) and autophagy induction. Autophagy Reports, 2 (1). 2166324. ISSN 2769-4127 doi: https://doi.org/10.1080/27694127.2023.2166324 Mitry, Madonna M. A., Greco, Francesca and Osborn, Helen M. I. (2023) In vivo applications of bioorthogonal reactions- chemistry and targeting mechanisms. Chemistry - A European Journal, 29 (20). e202203942. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.202203942 Mitry, Madonna M.A., Boateng, Samuel Y., Greco, Francesca and Osborn, Helen M. I. (2023) Bioorthogonal activation of prodrugs, for the potential treatment of breast cancer, using the Staudinger reaction. RSC Medicinal Chemistry. ISSN 2632-8682 doi: https://doi.org/10.1039/D3MD00137G
Pozza, Maria Dalla, Mesdom, Pierre, Abdullrahman, Ahmad, Prieto Otoya, Tayler D., Arnoux, Philippe, Frochot, Céline 2022
Albadawi, Dina A. I., Ravishankar, Divyashree, Vallance, Thomas M., Patel, Ketan, Osborn, Helen M. I. and Vaiyapuri, Sakthivel Allman, Sarah, Cordy, Joanna, Hall, James, Kleanthous, Vicky and Lander, Lizzy (2022) Exploring the perception of additional information content in 360° 3D VR video for teaching and learning. Virtual Worlds, 1 (1). pp. 1-17. ISSN 2813-2084 doi: https://doi.org/10.3390/virtualworlds1010001 Baker, Ysobel R., Thorpe, Cameron, Chen, Jinfeng, Poller, Laura M., Cox, Lina, Kumar, Pawan, Lim, Wooi F., Lie, Lillian, McClorey, Graham, Epple, Sven, Singleton, Daniel, McDonough, Michael A., Hardwick, Jack S., Christensen, Kirsten E., Wood, Matthew J. A., Hall, James P., El-Sagheer, Afaf H. and Brown, Tom (2022) An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nature Communications, 13. pp. 1-13. ISSN 2041-1723 doi: https://doi.org/10.1038/s41467-022-31636-2
Cheeseman, Jack, Badia, Concepcion, Thomson, Rebecca I., Kuhnle, Gunter
Dalla Pozza, Maria, Abdullrahman, Ahmad, Cardin, Christine J. Hutchins, Mark, Bovill, Richard A., Stephens, Peter J., Brazier, John A. and Osborn, Helen M. I. (2022) Glycosides of nadifloxacin—synthesis and antibacterial activities against methicillin-resistant Staphylococcus aureus. Molecules, 27 (5). 1504. ISSN 1420-3049 doi: https://doi.org/10.3390/molecules27051504
Khater, Mai, Watson, Kimberly A.
McQuaid, Kane T., Takahashi, Shuntaro, Baumgaertner, Lena, Cardin, David J., Paterson, Neil G., Hall, James P., Sugimoto, Naoki and Cardin, Christine J.
Ridzuan, Noridzzaida, Widera, Darius
Skurikhin, Evgenii G., Pershina, Olga
Trinh, Duong N., Radlinskaite, Meda, Cheeseman, Jack, Kuhnle, Gunter 2021Babra, Tahkur, Warriner, Colin, Bazin, Nicholas, Hayes, Wayne and Greenland, Barny (2021) A fluoride degradable crosslinker for debond-on-demand polyurethane based crosslinked adhesives. Materials Today Communications, 26. 101777. ISSN 2352-4928 doi: https://doi.org/10.1016/j.mtcomm.2020.101777
Cheeseman, Jack, Kuhnle, Gunter
Cheeseman, Jack, Kuhnle, Gunter Dawood, Dina H., Srour, Aladdin M., Saleh, Dalia O., Huff, Kelley J., Greco, Francesca and Osborn, Helen M. I. (2021) New pyridine and chromene scaffolds as potent vasorelaxant and anticancer agents. RSC Advances, 11. pp. 29441-29452. ISSN 2046-2069 doi: https://doi.org/10.1039/D1RA04758B Manzoni, Claudia and Ferrari, Raffaele (2021) Mendelian and sporadic FTD: disease risk and avenues from genetics to disease pathways through in silico modelling. In: Ghetti, Bernardino, Buratti, Emanuele, Boeve, Bradley and Rademakers, Rosa (eds.) Frontotemporal Dementias. Advances in Experimental Medicine and Biology, 1281. Springer, pp. 283-296. ISBN 9783030511395 doi: https://doi.org/10.1007/978-3-030-51140-1_17 2020Baptista, Frederico R., Devereux, Stephen J., Gurung, Sarah P., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Brazier, John A., Kelly, John M. and Quinn, Susan J. (2020) The influence of loops on the binding of the [Ru(phen)2dppz]2+ light-switch compound to i-motif DNA structures revealed by time-resolved spectroscopy. Chemical Communications, 56 (67). pp. 9703-9706. ISSN 1359-7345 doi: https://doi.org/10.1039/D0CC03702H Council, Claire E., Kilpin, Kelly J., Gusthart, Jessica S., Allman, Sarah A., Linclau, Bruno and Lee, Seung Seo (2020) Enzymatic glycosylation involving fluorinated carbohydrates. Organic & Biomolecular Chemistry, 18 (18). pp. 3423-3451. ISSN 1477-0520 doi: https://doi.org/10.1039/D0OB00436G Hall, James P. and Allman, Sarah A. (2020) Blending virtual reality with traditional approaches to encourage engagement with core chemistry concepts relevant to an undergraduate pharmacy curriculum. Pharmacy Education, 20 (1). pp. 365-374. ISSN 1477-2701 doi: https://doi.org/10.46542/pe.2020.201.365374 Khater, Mai, Greco, Francesca and Osborn, Helen M. I. (2020) Antiangiogenic activity of flavonoids: a systematic review and meta-analysis. Molecules, 25 (20). 4712. ISSN 1420-3049 doi: https://doi.org/10.3390/molecules25204712 Natfji, Az Alddien, Nikitin, Dmitry O., Semina, Irina I., Moustafine, Rouslan I., Khutoryanskiy, Vitaliy V., Lin, Hong, Stephens, Gary J., Watson, Kimberly A., Osborn, Helen M. I. and Greco, Francesca (2020) Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects. Journal of Controlled Release, 322. pp. 227-235. ISSN 0168-3659 doi: https://doi.org/10.1016/j.jconrel.2020.02.037 Tomkins, James E. (2020) Defining the Proximal Interactome of Death-Associated Protein Kinase 1. PhD thesis, University of Reading. doi: https://doi.org/10.48683/1926.00104248 2019Conlon, Patrick F., Eguaogie, Olga, Wilson, Jordan, Sweet, Jamie S. T., Steinhögl, Julian, Englert, Klaudia, Hancox, Oliver G. A., Law, Christopher J., Allman, Sarah A., Tucker, James H. R., Hall, James P. and Vyle, Joseph S. (2019) Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography. Chemical Science, 10 (47). pp. 10948-10957. ISSN 1478-6524 doi: https://doi.org/10.1039/C9SC04098F Howse, G. L., Bovill, R. A., Stephens, P. J. and Osborn, Helen M. I. (2019) Synthesis and antibacterial profiles of targeted triclosan derivatives. European Journal of Medicinal Chemistry, 162. pp. 51-58. ISSN 0223-5234 doi: https://doi.org/10.1016/j.ejmech.2018.10.053 Khater, Mai, Ravishankar, Divyashree, Greco, Francesca and Osborn, Helen (2019) Metal complexes of flavonoids: their synthesis, characterization, and enhanced anti-oxidant and anti-cancer activities. Future Medicinal Chemistry, 11 (21). ISSN 1756-8927 doi: https://doi.org/10.4155/fmc-2019-0237 McQuaid, Kane, Hall, James P., Baumgaertner, Lena, Cardin, David J. and Cardin, Christine J. (2019) Three thymine/adenine binding modes of the ruthenium complex Λ-[Ru (TAP)2(dppz)]2+ to the G-quadruplex forming sequence d(TAGGGTT) shown by X-ray crystallography. Chemical Communications, 55. pp. 9116-9119. ISSN 1359-7345 doi: https://doi.org/10.1039/C9CC04316K McQuaid, Kane, Abell, Holly, Gurung, Sarah P., Allan, David R., Winter, Graeme, Sorensen, Thomas, Cardin, David J., Brazier, John A., Cardin, Christine J. and Hall, James P. (2019) Structural studies reveal the enantiospecific recognition of a DNA G-quadruplex by a ruthenium polypyridyl complex. Angewandte Chemie International Edition, 58 (29). pp. 9881-9885. ISSN 1433-7851 doi: https://doi.org/10.1002/anie.201814502 Strohfeldt, Katja (2019) The power of the virtual client – using problem-based learning as a tool for integration in a pharmaceutical sciences laboratory course. Higher Education Pedagogies, 4 (1). pp. 462-475. ISSN 2375-2696 doi: https://doi.org/10.1080/23752696.2019.1686647 Vallance, Thomas M., Ravishankar, Divyashree, Albadawi, Dina A. I., Osborn, Helen M. I. and Vaiyapuri, Sakthivel (2019) Synthetic flavonoids as novel modulators of platelet function and thrombosis. International Journal of Molecular Sciences, 20 (12). e3106. ISSN 1422-0067 doi: https://doi.org/10.3390/ijms20123106 2018Bootman, Martin D., Allman, Sarah, Rietdorf, Katja and Bultynck, Geert (2018) Deleterious effects of calcium indicators within cells: an inconvenient truth. Cell Calcium, 73. pp. 82-87. ISSN 0143-4160 doi: https://doi.org/10.1016/j.ceca.2018.04.005 Brown, Geoffrey D., Bauer, Julia, Osborn, Helen M. I. and Kuemmerle, Rainer (2018) A solution NMR approach to determine the chemical structures of carbohydrates using the hydroxyl groups as starting points. ACS Omega, 3 (12). pp. 17957-17975. ISSN 2470-1343 doi: https://doi.org/10.1021/acsomega.8b02136 Murray, Claire A., Zhu, Zhixue, Cardin, Christine J., Colquhoun, Howard M. and Greenland, Barnaby W. (2018) Quadruple stacking of macrocyclic viologen radical-cations. Supramolecular Chemistry, 30 (9). pp. 751-757. ISSN 1061-0278 doi: https://doi.org/10.1080/10610278.2017.1375113 Parker, Matthew P., Murray, Claire A., Hart, Lewis R., Greenland, Barny W., Hayes, Wayne, Cardin, Christine J. and Colquhoun, Howard M. (2018) Mutual complexation between π-π stacked molecular tweezers. Crystal Growth and Design, 18 (1). pp. 386-392. ISSN 1528-7505 doi: https://doi.org/10.1021/acs.cgd.7b01376 Stachulski, Andrew V., Santoro, M. Gabriella, Piacentini, Sara, Belardo, Giuseppe, La Frazia, Simone, Pidathala, Chandrakala, Row, Eleanor C., Berry, Neil G., Iqbal, Mazhar, Allman, Sarah A., Semple, J.Edward, Eklov, Brian M., O'Neill, Paul M. and Rossignol, Jean-Francois (2018) Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus. Future Medicinal Chemistry, 10 (8). pp. 851-862. ISSN 1756-8927 doi: https://doi.org/10.4155/fmc-2017-0217 2017Hall, James P., Gurung, Sarah P., Henle, Jessica, Poidl, Patrick, Andersson, Johanna, Lincoln, Per, Winter, Graeme, Sorensen, Thomas, Cardin, David J., Brazier, John A. and Cardin, Christine J. (2017) Guanine can direct binding specificity of Ru-dppz complexes to DNA through steric effects. Chemistry: A European Journal, 23 (21). pp. 4981-4985. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.201605508 Hart, Lewis R., Hayes, Wayne and Greenland, Barnaby W. (2017) Polymeric materials based on NDI and its congeners. In: Pantos, G. Dan (ed.) Naphthalenediimide and its Congeners: From Molecules to Materials. Monographs in Supramolecular Chemistry. Royal Society of Chemistry, London, pp. 167-217. ISBN 9781849739221 doi: https://doi.org/10.1039/9781782621386-00167 Natfji, Az Alddien, Osborn, Helen M. I. and Greco, Francesca (2017) Feasibility of polymer-drug conjugates for non-cancer applications. Current Opinion in Colloid & Interface Science, 31. pp. 51-66. ISSN 1359-0294 doi: https://doi.org/10.1016/j.cocis.2017.07.004 Natfji, Az Alddien, Ravishankar, Divyashree, Osborn, Helen M. I. and Greco, Francesca (2017) Parameters affecting the enhanced permeability and retention effect: the need for patient selection. Journal of Pharmaceutical Sciences, 106 (11). pp. 3179-3187. ISSN 0022-3549 doi: https://doi.org/10.1016/j.xphs.2017.06.019 Ravishankar, Divyashree, Salamah, Maryam, Attina, Alda, Pothi, Radhika, Vallance, Thomas M., Javed, Muhammad, Williams, Harry F., Alzahrani, Eman M. S., Kabova, Elena, Vaiyapuri, Rajendran, Shankland, Kenneth, Gibbins, Jonathan, Strohfeldt, Katja, Greco, Francesca, Osborn, Helen M. I. and Vaiyapuri, Sakthivel (2017) Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy. Scientific Reports, 7. 5738. ISSN 2045-2322 doi: https://doi.org/10.1038/s41598-017-05936-3 Takahashi, Shuntaro, Brazier, John A. and Sugimoto, Naoki (2017) Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America, 114 (36). pp. 9605-9610. ISSN 0027-8424 doi: https://doi.org/10.1073/pnas.1704258114 Thomson, Rebecca I., Gardner, Richard A., Strohfeldt, Katja, Fernandes, Daryl L., Stafford, Graham P., Spencer, Daniel I. R. and Osborn, Helen M. I. (2017) Analysis of three epoetin alpha products by LC and LC-MS indicates differences in glycosylation critical quality attributes, including sialic acid content. Analytical Chemistry, 89 (12). pp. 6455-6462. ISSN 0003-2700 doi: https://doi.org/10.1021/acs.analchem.7b00353 2016Al-Ani, Widad, Shankland, Kenneth and Cobb, Andre J. A. (2016) Asymmetric organocatalytic synthesis of cyclopentane γ-nitroketones. Synlett, 27 (1). pp. 17-20. ISSN 0936-5214 doi: https://doi.org/10.1055/s-0035-1560504 Bovill, Richard, Evans, P. G., Howse, G. L. and Osborn, Helen M. I. (2016) Synthesis and biological analysis of novel glycoside derivatives of L-AEP, as targeted antibacterial agents. Bioorganic & Medicinal Chemistry Letters, 26 (15). pp. 3774-3779. ISSN 0960-894X doi: https://doi.org/10.1016/j.bmcl.2016.05.052 Bryant, Laura A., Fanelli, Rossana and Cobb, Alexander J. A. (2016) Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts. Beilstein Journal of Organic Chemistry, 12. pp. 429-443. ISSN 1860-5397 doi: https://doi.org/10.3762/bjoc.12.46 Chen, Long, Willcock, Helen, Wedge, Christopher J., Hartl, Frantisek, Colquhoun, Howard M. and Greenland, Barny W. (2016) Efficient access to conjugated 4,4’-bipyridinium oligomers using the Zincke reaction: synthesis, spectroscopic and electrochemical properties. Organic and Biomolecular Chemistry, 14 (3). pp. 980-988. ISSN 1477-0520 doi: https://doi.org/10.1039/c5ob02211h Hall, James P., Keane, Paraic M., Beer, Hanna, Buchner, Katrin, Winter, Graeme, Sorensen, Thomas L., Cardin, David J., Brazier, John A. and Cardin, Christine J. (2016) Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes. Nucleic Acids Research, 44 (19). pp. 9472-9482. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkw753 Heath, Felicity, Newman, Amy, Clementi, Chiara, Pasut, Gianfranco, Lin, Hong, Stephens, Gary J., Whalley, Ben J., Osborn, Helen M. I. and Greco, Francesca (2016) A novel PEG–haloperidol conjugate with a non-degradable linker shows the feasibility of using polymer–drug conjugates in a non-prodrug fashion. Polymer Chemistry, 7 (47). pp. 7204-7210. ISSN 1759-9954 doi: https://doi.org/10.1039/c6py01418f Keane, Paraic M., Baptista, Frederico R., Gurung, Sarah P., Devereux, Stephen J., Sazanovich, Igor V., Towrie, Michaal, Brazier, John A., Cardin, Christine J., Kelly, John M. and Quinn, Susan J. (2016) Long-lived excited-state dynamics of i-motif structures probed by time-resolved infrared spectroscopy. ChemPhysChem, 17 (9). pp. 1281-1287. ISSN 1439-7641 doi: https://doi.org/10.1002/cphc.201501183 Parshotam, Jay P., Brazier, John A., Bovill, Richard and Osborn, Helen M. I. (2016) An efficient and rapid microwave-assisted synthesis of 1-acetyl-1H-indol-3-YL acetates. Current Microwave Chemistry, 3 (3). pp. 247-257. ISSN 2213-3364 doi: https://doi.org/10.2174/2213335603666160108001556 Ravishankar, Divyashree, Corona, Giulia, Hogan, Stephanie M., Spencer, Jeremy P. E., Greco, Francesca and Osborn, Helen M. I. (2016) Thioflavones as novel neuroprotective agents. Bioorganic & Medicinal Chemistry, 24 (21). pp. 5513-5520. ISSN 0968-0896 doi: https://doi.org/10.1016/j.bmc.2016.09.006 Ravishankar, Divyashree, Watson, Kim A., Greco, Francesca and Osborn, Helen M. I. (2016) Novel synthesised flavone derivatives provide significant insight into the structural features required for enhanced anti-proliferative activity. RSC Advances, 6 (69). pp. 64544-64556. ISSN 2046-2069 doi: https://doi.org/10.1039/C6RA11041J Sinclair, Fern, Chen, Long, Greenland, Barnaby W. and Shaver, Michael P. (2016) Installing multiple functional groups on biodegradable polyesters via post-polymerization olefin cross-metathesis. Macromolecules, 49 (18). pp. 6826-6834. ISSN 0024-9297 doi: https://doi.org/10.1021/acs.macromol.6b01571 2015Aitken, Lewis S., Hammond, Lisa E., Sundaram, Rajkumar, Shankland, Kenneth, Brown, Geoffrey D. and Cobb, Andre J. A. (2015) Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to d3-amino acids. Chemical Communications, 51 (70). pp. 13558-13561. ISSN 1359-7345 doi: https://doi.org/10.1039/c5cc05158d Bauer, Julia and Osborn, Helen M. I. (2015) Sialic acids in biological and therapeutic processes: opportunities and challenges. Future Medicinal Chemistry, 7 (16). pp. 2285-2299. ISSN 1756-8927 doi: https://doi.org/10.4155/fmc.15.135 Gadd, Adam J. R., Greco, Francesca, Cobb, Alexander J. A. and Edwards, Alexander D. (2015) Targeted activation of toll-like receptors: conjugation of a toll-like receptor 7 agonist to a monoclonal antibody maintains antigen binding and specificity. Bioconjugate Chemistry, 26 (8). pp. 1743-1752. ISSN 1043-1802 doi: https://doi.org/10.1021/acs.bioconjchem.5b00302 Greenland, Barny W. and Hayes, Wayne (2015) Donor-acceptor π−π stacking interactions: from small molecule complexes to healable supramolecular polymer networks. In: Supramolecular polymer networks and gels. Advances in Polymer Science. Springer, pp. 143-166. Gurung, Sarah P., Schwarz, Christine, Hall, James P., Cardin, Christine J. and Brazier, John A. (2015) The importance of loop length on the stability of i-motif structures. Chemical Communications, 51 (26). pp. 5630-5632. ISSN 1359-7345 doi: https://doi.org/10.1039/C4CC07279K Hall, James P., Poynton, Fergus E., Keane, Paraic M., Gurung, Sarah P., Brazier, John A., Cardin, David J., Winter, Graeme, Gunnlaugsson, Thorfinnur, Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Kelly, John M. and Quinn, Susan J. (2015) Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy. Nature Chemistry, 7. pp. 961-967. ISSN 1755-4330 doi: https://doi.org/10.1038/nchem.2369 Kikuta, Kenji, Piao, Haishun, Brazier, John, Taniguchi, Yosuke, Onizuka, Kazumitsu, Nagatsugi, Fumi and Sasaki, Shigeki (2015) Stabilization of the i-motif structure by the intra-strand cross-link formation. Bioorganic & Medicinal Chemistry Letters, 25 (16). pp. 3307-3310. ISSN 0960-894X doi: https://doi.org/10.1016/j.bmcl.2015.05.064 MacDonald, J. P., Parker, M. P., Greenland, B. W., Hermida-Merino, D., Hamley, I. W. and Shaver, M. P. (2015) Tuning thermal properties and microphase separation in aliphatic polyester ABA copolymers. Polymer Chemistry, 6 (9). pp. 1445-1453. ISSN 1759-9954 doi: https://doi.org/10.1039/c4py01459f Olorunniji, Femi J., McPherson, Arlene L., Pavlou, Hania J., McIlwraith, Michael J., Brazier, John, Cosstick, Richard and Stark, W. Marshall (2015) Nicked-site substrates for a serine recombinase reveal enzyme–DNA communications and an essential tethering role of covalent enzyme–DNA linkages. Nucleic Acids Research, 43 (12). pp. 6134-6143. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gkv521 Ravishankar, Divyashree, Watson, Kimberly A., Boateng, Samuel Y., Green, Rebecca J., Greco, Francesca and Osborn, Helen M.I. (2015) Exploring quercetin and luteolin derivatives as antiangiogenic agents. European Journal of Medicinal Chemistry, 97. pp. 259-274. ISSN 0223-5234 doi: https://doi.org/10.1016/j.ejmech.2015.04.056 Strohfeldt, Katja and Khutoryanskaya, Olga (2015) Using problem-based learning in a chemistry practical class for pharmacy students and engaging them with feedback. American Journal of Pharmaceutical Education, 79 (9). 141. ISSN 1553-6467 doi: https://doi.org/10.5688/ajpe799141 2014Dell'Isola, Antonio, McLachlan, Matthew M. W., Neuman, Benjamin W., Al-Mullah, Hawaa M. N., Binks, Alexander W. D., Elvidge, Warren, Shankland, Kenneth and Cobb, Alexander J. A. (2014) Synthesis and antiviral properties of spirocyclic [1,2,3]-triazolooxazine nucleosides. Chemistry- A European Journal, 20 (37). pp. 11685-11689. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.201403560 Hart, Lewis R., Hunter, James H, Nguyen, Ngoc A, Harries, Josephine L, Greenland, Barnaby W., Mackay, Michael E, Colquhoun, Howard M. and Hayes, Wayne (2014) Multivalency in healable supramolecular polymers: the effect of supramolecular cross-link density on the mechanical properties and healing of noncovalent polymer networks. Polymer Chemistry, 5 (11). pp. 3680-3688. ISSN 1759-9954 doi: https://doi.org/10.1039/C4PY00292J Harvey, David J., Edgeworth, Matthew, Krishna, Benjamin A., Bonomelli, Camille, Allman, Sarah A., Crispin, Max and Scrivens, James H. (2014) Fragmentation of negative ions from N-linked carbohydrates: Part 6. Glycans containing oneN-acetylglucosamine in the core. Rapid Communications in Mass Spectrometry, 28 (18). pp. 2008-2018. ISSN 0951-4198 doi: https://doi.org/10.1002/rcm.6980 Rajora, Amit K., Ravishankar, Divyashree, Osborn, Helen M.I. and Greco, Francesca (2014) Impact of the enhanced permeability and retention (EPR) effect and cathepsins levels on the activity of polymer-drug conjugates. Polymers, 6 (8). pp. 2186-2220. ISSN 2073-4360 doi: https://doi.org/10.3390/polym6082186 Steinke, Joachim H. G., Greenland, Barnaby W., Johns, Stephen, Parker, Matthew P., Atkinson, Robert C. J., Cade, Ian A. and Trussell, Stephen J. (2014) Robust and operationally simple synthesis of Poly(bis(2,2,2- trifluoroethoxy) phosphazene) with controlled molecular weight, low PDI, and high conversion. ACS Macro Letters, 3. pp. 548-551. ISSN 2161-1653 doi: https://doi.org/10.1021/mz500199x Vaiyapuri, Rajendran, Greenland, Barnaby, Colquhoun, Howard M., Elliott, Joanne M. and Hayes, Wayne (2014) Evolution of supramolecular healable composites: a minireview. Polymer International, 63 (6). pp. 933-942. ISSN 0959-8103 doi: https://doi.org/10.1002/pi.4685 2013Alonzi, D. S., Kukushkin, N. V., Allman, S. A., Hakki, Z., Williams, S. J., Pierce, L., Dwek, R. A. and Butters, T. D. (2013) Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins. Cellular and Molecular Life Sciences, 70 (15). pp. 2799-2814. ISSN 1420-682X doi: https://doi.org/10.1007/s00018-013-1304-6 Bajaj, N., Hart, L. R., Greenland, B. W. and Hayes, Wayne (2013) Urea organogelators: synthesis and properties. Macromolecular Symposia, 329 (1). pp. 118-124. ISSN 1022-1360 doi: https://doi.org/10.1002/masy.201200103 Cheng, Ge, Greenland, Barnaby W., Lampard, Chris, Williams, Neal, Bahra, Malkit S. and Hayes, Wayne (2013) Lightly branched comb polyesters: application in fast drying solvent-borne coating formulations. Reactive & Functional Polymers, 73 (4). pp. 619-623. ISSN 1381-5148 doi: https://doi.org/10.1016/j.reactfunctpolym.2013.01.008 Cheng, Ge, Greenland, Barnaby W., Lampard, Chris, Williams, Neil, Barhra, Malkit S. and Hayes, Wayne (2013) Synthesis of novel hyperbranched polymers featuring oxazoline linear units and their application in fast-drying solvent-borne coating formulations. Journal of Polymer Science Part A: Polymer Chemistry, 51 (18). pp. 3964-3974. ISSN 1099-0518 doi: https://doi.org/10.1002/pola.26807 Cobb, Andre, Arezki, Natasha, Dell'Isola, Antonio and Aitken, Lewis (2013) Asymmetric organocatalysis and the nitro group functionality. Synthesis-Stuttgart, 45 (19). pp. 2627-2648. ISSN 0039-7881 doi: https://doi.org/10.1055/s-0033-1338522 Greenland, Barnaby W and Hayes, Wayne (2013) Healable polymeric materials. In: Greenland, Barnaby W and Hayes, Wayne (eds.) Healable polymer systems. Royal Society of Chemistry, London, pp. 1-15. ISBN 9781849736268 doi: https://doi.org/10.1039/9781849737470-00001 Greenland, Barnaby W., Bird, Matthew B., Burattini, Stefano, Cramer, Rainer, O'Reilly, Rachel K., Patterson, Joseph P., Hayes, Wayne, Cardin, Christine J. and Colquhoun, Howard M. (2013) Mutual binding of polymer end-groups by complementary π–π-stacking: a molecular “Roman Handshake”. Chemical Communications, 49 (5). pp. 454-456. ISSN 1359-7345 doi: https://doi.org/10.1039/C2CC35965K Greenland, Barnaby W., Fiore, Gina L., Rowan, Stuart J. and Weder, Christoph (2013) Healable supramolecular polymeric materials. In: Hayes, Wayne and Greenland, Barnaby W. (eds.) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp. 92-125. ISBN 9781849736268 doi: https://doi.org/10.1039/9781849737470-00092 Hart, Lewis R., Harries, J. L., Greenland, Barnaby W., Colquhoun, Howard M. and Hayes, Wayne (2013) Healable supramolecular polymers. Polymer Chemistry, 4. pp. 4860-4870. ISSN 1759-9954 doi: https://doi.org/10.1039/C3PY00081H Hayes, Wayne and Greenland, Barnaby W., eds. (2013) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp165. ISBN 9781849736268 Jarvis, Ashley N., McClaren, Andrew B., Osborn, Helen M. I. and Sweeney, Joseph (2013) Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines. Beilstein Journal of Organic Chemistry, 9. pp. 852-859. ISSN 1860-5397 doi: https://doi.org/10.3762/bjoc.9.98 Murray, Claire A., Cardin, Christine J., Greenland, Barny W., Swift, Andrew and Colquhoun, Howard M. (2013) Pairwise assembly of organopalladium(II) units with cyanurato(3-) and trithiocyanurato(3-) ligands: formation of chiral Pd12, Pd10 and Pd9 cage-molecules. Inorganic Chemistry, 52 (18). pp. 10424-10430. ISSN 0020-1669 doi: https://doi.org/10.1021/ic401253q Rajkumar, Sundaram, Shankland, Kenneth, Goodman, Jonathan M. and Cobb, Alexander J.A. (2013) Organocatalytic domino reaction of cyanosulfones: access to complex cyclohexane systems with quaternary carbon centers. Organic Letters, 15 (6). pp. 1386-1389. ISSN 1523-7060 doi: https://doi.org/10.1021/ol400356k Ravishankar, Divya, Rajora, Amit, Greco, Francesca and Osborn, Helen (2013) Flavonoids as prospective compounds for anti-cancer therapy. International Journal of Biochemistry and Cell Biology, 45 (12). pp. 2821-2831. ISSN 1878-5875 doi: https://doi.org/10.1016/j.biocel.2013.10.004 Vaiyapuri, Rajendran, Greenland, Barnaby W, Colquhoun, Howard M, Elliott, Joanne E and Hayes, Wayne (2013) Molecular recognition between functionalized gold nanoparticles and healable, supramolecular polymer blends – a route to property enhancement. Polymer Chemistry, 4. pp. 4902-4909. ISSN 1759-9954 doi: https://doi.org/10.1039/c3py00086a 2012Brazier, John A., Shah, Arti and Brown, Geoffrey D. (2012) I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes. Chemical Communication, 48 (87). pp. 10739-10741. ISSN 1359-7345 doi: https://doi.org/10.1039/C2CC30863K Rajkumar, S., Shankland, Kenneth, Brown, Geoffrey D. and Cobb, Andre (2012) Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction. Chemical Science, 3. pp. 584-588. ISSN 1478-6524 doi: https://doi.org/10.1039/C1SC00592H Rangam, Gopinath, Schmitz, Kerstin-Maike, Cobb, Andre and Petersen-Mahrt, Svend (2012) AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud. PloS ONE, 7 (8). e43279. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0043279 Shaikh, Abdul K., Cobb, Andre J A and Varvounis, George (2012) Mild and rapid method for the generation of ortho-(naphtho)-quinone methide intermediates. Organic Letters, 14 (2). pp. 584-587. ISSN 1523-7060 doi: https://doi.org/10.1021/ol203196n 2011Benning, R. K., Osborn, Helen Mary Isted and Turkson, Andrea (2011) Regioselective Beckmann rearrangements of furanoside and pyranoside-derived oximes. Tetrahedron: Asymmetry, 22 (1). pp. 109-116. ISSN 0957-4166 doi: https://doi.org/10.1016/j.tetasy.2010.11.031 Burland, Peter A., Osborn, Helen M. I. and Turkson, Andrea (2011) Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes. Bioorganic & Medicinal Chemistry, 19 (18). pp. 5679-5692. ISSN 0968-0896 doi: https://doi.org/10.1016/j.bmc.2011.07.019 Cobb, Andre (2011) General aspects of organocatalytic cyclizations. In: Mahrwald, Rainer (ed.) Enantioselective Organocatalyzed Reactions II: Asymmetric C-C Bond Formation Processes. Springer, pp. 1-40. ISBN 9789048138661 Fais, M., Karamanska, R., Allman, Sarah, Fairhurst, S. A., Innocenti, P., Fairbanks, A. J., Donohoe, T. J., Davis, B. G., Russell, D. A. and Field, R. A (2011) Surface plasmon resonance imaging of glycoarrays identifies novel and unnatural carbohydrate-based ligands for potential ricin sensor development. Chemical Science, 2 (10). pp. 1952-1959. ISSN 2041-6539 doi: https://doi.org/10.1039/c1sc00120e Fante, Cristina, Eldar-Boock, Anat, Satchi-Fainaro, Ronit, Osborn, Helen M. I. and Greco, Francesca (2011) Synthesis and biological evaluation of a polyglutamic acid-dopamine conjugate: a new antiangiogenic agent. Journal of Medicinal Chemistry, 54 (14). pp. 5255-5259. ISSN 0022-2623 doi: https://doi.org/10.1021/jm200382r Fern, S. E., Heath, Peter and Cobb, Alexander John Andre (2011) Aldol reaction of butane-2,3-diacetal protected methyl glycerate. Tetrahedron: Asymmetry, 22 (2). pp. 149-152. ISSN 0957-4166 doi: https://doi.org/10.1016/j.tetasy.2011.01.004 Rassmussen, T. S., Allman, Sarah, Twigg, G., Butters, T. D. and Jensen, H. H. (2011) Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease. Bioorganic & Medicinal Chemistry Letters, 21 (5). pp. 1519-1522. ISSN 0960-894X doi: https://doi.org/10.1016/j.bmcl.2010.12.106 Sarsam, Susan W., Nutt, David R., Strohfeldt, Katja and Watson, Kimberly A. (2011) Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study. Metallomics, 3 (2). pp. 152-161. ISSN 1756-5901 doi: https://doi.org/10.1039/c0mt00041h Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Lawrenson, A. S., Moores, S. L, Iqbal, M., Bentley, J., Allman, S., Edwards, G., Helm, A., Hellier, J., Korba, B. E., Semple, J. E. and Rossignol, J.-F. (2011) Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication. Journal of Medicinal Chemistry, 54 (24). pp. 8670-8680. ISSN 0022-2623 doi: https://doi.org/10.1021/jm201264t Stachulski, A.V., Pidathala, C., Row, E.C., Sharma, R., Berry, N.G., Iqbal, M., Bentley, J., Allman, S.A., Edwards, G., Helm, A., Hellier, J., Korba, B.E., Semple, J.E. and Rossignol, Jean-Francois (2011) Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication. Journal of Medicinal Chemistry, 54 (12). pp. 4119-4132. ISSN 0022-2623 doi: https://doi.org/10.1021/jm200153p 2010Bauer, JO, Stiller, J, Marques-Lopez, E, Strohfeldt, Katja Astrid, Christmann, M and Strohmann , C (2010) Silyl-Modified Analogues of 2-Tritylpyrrolidine: Synthesis and Applications in Asymmetric Organocatalysis. Chemistry - A European Journal, 16 (42). pp. 12553-12558. ISSN 0947-6539 doi: https://doi.org/10.1002/chem.201002166 Burland, P. A., Coisson, D. and Osborn, Helen Mary Isted (2010) Rapid synthesis of carbohydrate derivatives, including mimetics of c-linked disaccharides and c-Linked aza disaccharides, using the Hetero-Diels−Alder Reaction. Journal of Organic Chemistry, 75 (21). pp. 7210-7218. ISSN 0022-3263 doi: https://doi.org/10.1021/jo101219w Carlescu, Irina, Osborn, Helen M.I., Desbrieres, Jacques, Scutaru, Dan and Popa, Marcel (2010) Synthesis of poly(aspartimide)-based bio-glycoconjugates. Carbohydrate Research, 345 (1). pp. 33-40. ISSN 0008-6215 doi: https://doi.org/10.1016/j.carres.2009.08.034 Kolstoe, S. E., Mangione, P. P., Bellotti, V., Taylor, G. W., Tennent, G. A., Deroo, S., Morrison, A. J., Cobb, Alexander John Andre, Coyne, A., McCammon, M. G., Warner, T. D., Mitchell, J., Gill, R., Smith, M. D., Ley, S. V., Robinson, S. P. and Pepys, M. B. (2010) Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America, 107 (47). pp. 20483-20488. ISSN 0027-8424 doi: https://doi.org/10.1073/pnas.1008255107 Nodes, William J., Shankland, Kenneth, Rajkumar, Sundaram and Cobb, Alexander John Andre (2010) Asymmetric phase-transfer-catalyzed synthesis of five-membered cyclic gamma-Amino acid precursors. Synlett, 2010 (20). pp. 3011-3014. ISSN 1437-2096 doi: https://doi.org/10.1055/s-0030-1259050 Strohfeldt, Katja and Grant, Daniel T. (2010) A model for self-directed problem-based learning for renal therapeutics. American Journal of Pharmaceutical Education , 74 (9). Article 173. 2009Allman, S. A., Jensen, H. H., Vijayakrishnan, B., Garnett, J. A., Leon, E., Liu, Y., Anthony, D. C., Sibson, N. R., Feizi, T., Matthews, S. and Davis, B. G. (2009) Potent fluoro-oligosaccharide probes of adhesion in Toxoplasmosis. ChemBioChem, 10 (15). pp. 2522-2529. ISSN 1439-7633 doi: https://doi.org/10.1002/cbic.200900425 Garnett, James A., Liu, Yan, Leon, Ester, Allman, Sarah A., Friedrich, Nikolas, Saouros, Savvas, Curry, Stephen, Soldati-Favre, Dominique, Davis, Benjamin G., Feizi, Ten and Matthews, Stephen (2009) Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii. Protein Science, 18 (9). pp. 1935-1947. ISSN 0961-8368 doi: https://doi.org/10.1002/pro.204 Jawaid, Samaila, Khan, Tariq H., Osborn, Helen M. I. and Williams, Nana O. A. (2009) Tyrosinase activated melanoma prodrugs. Anti-cancer agents in medicinal chemistry, 9 (7). pp. 717-727. ISSN 1871-5206 Nodes, William, Nutt, David Richard, Chippindale, Ann Mary and Cobb, Alexander John Andre (2009) Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters. Journal of the American Chemical Society, 131 (44). pp. 16016-16017. ISSN 0002-7863 doi: https://doi.org/10.1021/ja9070915 Osborn, Helen M. I. and Turkson, Andrea (2009) Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside. Tetrahedron Asymmetry, 20 (18). pp. 2162-2166. ISSN 0957-4166 doi: https://doi.org/10.1016/j.tetasy.2009.08.004 Vessieres, Anne, Plamont, Marie-Aude, Cabestaing, Claude, Claffey, James, Dieckmann, Sandra, Hogan, Megan, Mueller-Bunz, Helge, Strohfeldt, Katja Astrid and Tacke, Matthias (2009) Proliferative and anti-proliferative effects of titanium- and iron-based metallocene anti-cancer drugs. Journal of Organometallic Chemistry , 694 (6). pp. 874-879. ISSN 0022-328X doi: https://doi.org/10.1016/j.jorganchem.2008.11.071 2008Baksh, Mohamed Fazilluddeen and Kelly, Patrick (2008) Statistical methods for examining genetic influences of resistance to anti-epileptic drugs. Expert Review of Clinical Pharmacology, 1 (1). pp. 137-144. ISSN 1751-2433 doi: https://doi.org/10.1586/17512433.1.1.137 Bonjoch, Josep, Drew, Michael G.B., Gonzalez, Asensio, Greco, Francesca, Jawaid, Samaila, Osborn, Helen Mary Isted, Williams, Nana A.O. and Yaqoob, Parveen (2008) Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma. Journal of Medicinal Chemistry, 51 (20). pp. 6604-6608. ISSN 0022-2623 doi: https://doi.org/10.1021/jm8007745 Ellis, David, Norman, Sarah Ellen and Osborn, Helen Mary Isted (2008) Synthesis of S-linked carbohydrate analogues via a Ferrier reaction. Tetrahedron, 64 (12). pp. 2832-2854. ISSN 0040-4020 doi: https://doi.org/10.1016/j.tet.2008.01.042 Strohfeldt, Katja Astrid and Tacke, Matthias (2008) Bioorganometallic fulvene-derived titanocene anti-cancer drugs. Chemical Society Reviews, 37 (6). pp. 1174-1187. ISSN 0306-0012 doi: https://doi.org/10.1039/b707310k 2007Campo, Vanessa Leiria, Carvalho, Ivone, Allman, Sarah, Davis, Benjamin G. and Field, Robert A. (2007) Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins. Organic & Biomolecular Chemistry, 5 (16). pp. 2645-2657. ISSN 1477-0520 doi: https://doi.org/10.1039/b707772f Gaynor, J. W., Brazier, John and Cosstick, R. (2007) Synthesis of 3 '-S-phosphorothiolate oligonucleotides for their potential use in RNA interference. Nucleosides Nucleotides & Nucleic Acids, 26 (6-7). pp. 709-712. ISSN 1525-7770 doi: https://doi.org/10.1080/15257770701490753 2005Brazier, J. A., Shibata, T., Townsley, J., Taylor, B. F., Frary, E., Williams, N. H. and Williams, D. M. (2005) Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation. Nucleic Acids Research, 33 (4). pp. 1362-1371. ISSN 1362-4962 doi: https://doi.org/10.1093/nar/gki254 |
