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Cheeseman, Jack, Badia, Concepcion, Elgood-Hunt, Georgia, Gardner, Richard, Trinh, Duong, Monopoli, Marco, Kuhnle, Gunter ORCID logoORCID:, Spencer, Daniel and Osborn, Helen (2023) Elevated concentrations of Neu5Ac and Neu5,9Ac2 in human plasma: potential biomarkers of cardiovascular disease. Glycoconjugate Journal. ISSN 1573-4986 (In Press)

Khater, Mai, Brazier, John, Greco, Francesca and Osborn, Helen (2023) Anticancer evaluation of new organometallic ruthenium(II) flavone complexes. Medicinal Chemistry, 14 (2). pp. 253-267. ISSN 2632-8682 doi:

Kramer, H.B.R. and Allman, Sarah Ann (2023) Sugar coating autophagy: exploring the links between the inhibition of NGLY1 (N-glycanase 1) and autophagy induction. Autophagy Reports, 2 (1). 2166324. ISSN 2769-4127 doi:

Mitry, Madonna M. A., Greco, Francesca and Osborn, Helen M. I. (2023) In vivo applications of bioorthogonal reactions- chemistry and targeting mechanisms. Chemistry - A European Journal, 29 (20). e202203942. ISSN 0947-6539 doi:

Mitry, Madonna M.A., Boateng, Samuel Y., Greco, Francesca and Osborn, Helen M. I. (2023) Bioorthogonal activation of prodrugs, for the potential treatment of breast cancer, using the Staudinger reaction. RSC Medicinal Chemistry. ISSN 2632-8682 doi:

Pozza, Maria Dalla, Mesdom, Pierre, Abdullrahman, Ahmad, Prieto Otoya, Tayler D., Arnoux, Philippe, Frochot, Céline ORCID logoORCID:, Niogret, Germain, Saubaméa, Bruno, Burckel, Pierre, Hall, James P. ORCID logoORCID:, Hollenstein, Marcel ORCID logoORCID:, Cardin, Christine J. ORCID logoORCID: and Gasser, Gilles ORCID logoORCID: (2023) Increasing the π-expansive ligands in ruthenium(II) polypyridyl complexes: synthesis, characterization, and biological evaluation for photodynamic therapy applications. Inorganic Chemistry, 62 (45). pp. 18510-18523. ISSN 1520-510X doi:


Albadawi, Dina A. I., Ravishankar, Divyashree, Vallance, Thomas M., Patel, Ketan, Osborn, Helen M. I. and Vaiyapuri, Sakthivel ORCID logoORCID: (2022) Impacts of commonly used edible plants on the modulation of platelet function. International Journal of Molecular Sciences, 23 (2). 605. ISSN 1422-0067 doi:

Allman, Sarah, Cordy, Joanna, Hall, James, Kleanthous, Vicky and Lander, Lizzy (2022) Exploring the perception of additional information content in 360° 3D VR video for teaching and learning. Virtual Worlds, 1 (1). pp. 1-17. ISSN 2813-2084 doi:

Baker, Ysobel R., Thorpe, Cameron, Chen, Jinfeng, Poller, Laura M., Cox, Lina, Kumar, Pawan, Lim, Wooi F., Lie, Lillian, McClorey, Graham, Epple, Sven, Singleton, Daniel, McDonough, Michael A., Hardwick, Jack S., Christensen, Kirsten E., Wood, Matthew J. A., Hall, James P., El-Sagheer, Afaf H. and Brown, Tom (2022) An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides. Nature Communications, 13. pp. 1-13. ISSN 2041-1723 doi:

Cheeseman, Jack, Badia, Concepcion, Thomson, Rebecca I., Kuhnle, Gunter ORCID logoORCID:, Gardner, Richard A., Spencer, Daniel I. R. and Osborn, Helen M. I. (2022) Quantitative standards of 4-O acetyl and 9-O acetyl N-acetyl neuraminic acid for the analysis of plasma and serum. ChemBioChem, 23 (5). e202100662. ISSN 1439-7633 doi:

Dalla Pozza, Maria, Abdullrahman, Ahmad, Cardin, Christine J. ORCID logoORCID:, Gasser, Gilles and Hall, James P. ORCID logoORCID: (2022) Three’s a crowd – stabilisation, structure, and applications of DNA triplexes. Chemical Science (35). pp. 10193-10215. ISSN 2041-6539 doi:

Hutchins, Mark, Bovill, Richard A., Stephens, Peter J., Brazier, John A. and Osborn, Helen M. I. (2022) Glycosides of nadifloxacin—synthesis and antibacterial activities against methicillin-resistant Staphylococcus aureus. Molecules, 27 (5). 1504. ISSN 1420-3049 doi:

Khater, Mai, Watson, Kimberly A. ORCID logoORCID:, Boateng, Samuel Y., Greco, Francesca and Osborn, Helen M. I. (2022) Halogenated flavonoid derivatives display antiangiogenic activity. Molecules, 27 (15). 4757. ISSN 1420-3049 doi:

McQuaid, Kane T., Takahashi, Shuntaro, Baumgaertner, Lena, Cardin, David J., Paterson, Neil G., Hall, James P., Sugimoto, Naoki and Cardin, Christine J. ORCID logoORCID: (2022) Ruthenium polypyridyl complex bound to a unimolecular chair-form G-quadruplex. Journal of the American Chemical Society, 144 (13). pp. 5956-5964. ISSN 0002-7863 doi:

Ridzuan, Noridzzaida, Widera, Darius ORCID logoORCID: and Yahaya, Badrul Hisham (2022) Isolation and characterization of extracellular vesicles derived from human umbilical cord mesenchymal stem cells. In: Kannan, Nagarajan and Beer, Philip (eds.) Stem Cell Assays. Methods in Molecular Biology, 2429 (2429). Springer, pp. 271-280. ISBN 9781071619797 doi: (ISSN 1940-6029)

Skurikhin, Evgenii G., Pershina, Olga ORCID logoORCID:, Ermakova, Natalia, Pakhomova, Angelina ORCID logoORCID:, Widera, Darius ORCID logoORCID:, Zhukova, Mariia ORCID logoORCID:, Pan, Edgar ORCID logoORCID:, Sandrikina, Lubov, Kogai, Lena, Kushlinskii, Nikolai, Morozov, Sergey G., Kubatiev, Aslan and Dygai, Alexander (2022) Reprogrammed CD8+ T-lymphocytes isolated from bone marrow have anticancer potential in lung cancer. Biomedicines, 10 (6). 1450. ISSN 2227-9059 doi:

Trinh, Duong N., Radlinskaite, Meda, Cheeseman, Jack, Kuhnle, Gunter ORCID logoORCID:, Osborn, Helen M. I., Meleady, Paula, Spencer, Daniel I. R. and Monopoli, Marco P. (2022) Biomolecular corona stability in association with plasma cholesterol level. Nanomaterials, 12 (15). 2661. ISSN 2079-4991 doi:


Babra, Tahkur, Warriner, Colin, Bazin, Nicholas, Hayes, Wayne and Greenland, Barny (2021) A fluoride degradable crosslinker for debond-on-demand polyurethane based crosslinked adhesives. Materials Today Communications, 26. 101777. ISSN 2352-4928 doi:

Cheeseman, Jack, Kuhnle, Gunter ORCID logoORCID:, Stafford, Graham, Gardner, Richard, Spencer, Daniel and Osborn, Helen (2021) Sialic acid as a potential biomarker for cardiovascular disease, diabetes and cancer. Biomarkers in Medicine, 15 (11). pp. 911-928. ISSN 1752-0363 doi:

Cheeseman, Jack, Kuhnle, Gunter ORCID logoORCID:, Spencer, Daniel I.R. and Osborn, Helen (2021) Assays for the identification and quantification of sialic acids: challenges, opportunities and future perspectives. Bioorganic & Medicinal Chemistry, 30. 115882. ISSN 0968-0896 doi:

Dawood, Dina H., Srour, Aladdin M., Saleh, Dalia O., Huff, Kelley J., Greco, Francesca and Osborn, Helen M. I. (2021) New pyridine and chromene scaffolds as potent vasorelaxant and anticancer agents. RSC Advances, 11. pp. 29441-29452. ISSN 2046-2069 doi:

Manzoni, Claudia and Ferrari, Raffaele (2021) Mendelian and sporadic FTD: disease risk and avenues from genetics to disease pathways through in silico modelling. In: Ghetti, Bernardino, Buratti, Emanuele, Boeve, Bradley and Rademakers, Rosa (eds.) Frontotemporal Dementias. Advances in Experimental Medicine and Biology, 1281. Springer, pp. 283-296. ISBN 9783030511395 doi:


Baptista, Frederico R., Devereux, Stephen J., Gurung, Sarah P., Hall, James P., Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Brazier, John A., Kelly, John M. and Quinn, Susan J. (2020) The influence of loops on the binding of the [Ru(phen)2dppz]2+ light-switch compound to i-motif DNA structures revealed by time-resolved spectroscopy. Chemical Communications, 56 (67). pp. 9703-9706. ISSN 1359-7345 doi:

Council, Claire E., Kilpin, Kelly J., Gusthart, Jessica S., Allman, Sarah A., Linclau, Bruno and Lee, Seung Seo (2020) Enzymatic glycosylation involving fluorinated carbohydrates. Organic & Biomolecular Chemistry, 18 (18). pp. 3423-3451. ISSN 1477-0520 doi:

Hall, James P. and Allman, Sarah A. (2020) Blending virtual reality with traditional approaches to encourage engagement with core chemistry concepts relevant to an undergraduate pharmacy curriculum. Pharmacy Education, 20 (1). pp. 365-374. ISSN 1477-2701 doi:

Khater, Mai, Greco, Francesca and Osborn, Helen M. I. (2020) Antiangiogenic activity of flavonoids: a systematic review and meta-analysis. Molecules, 25 (20). 4712. ISSN 1420-3049 doi:

Natfji, Az Alddien, Nikitin, Dmitry O., Semina, Irina I., Moustafine, Rouslan I., Khutoryanskiy, Vitaliy V., Lin, Hong, Stephens, Gary J., Watson, Kimberly A., Osborn, Helen M. I. and Greco, Francesca (2020) Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects. Journal of Controlled Release, 322. pp. 227-235. ISSN 0168-3659 doi:

Tomkins, James E. (2020) Defining the Proximal Interactome of Death-Associated Protein Kinase 1. PhD thesis, University of Reading. doi:


Conlon, Patrick F., Eguaogie, Olga, Wilson, Jordan, Sweet, Jamie S. T., Steinhögl, Julian, Englert, Klaudia, Hancox, Oliver G. A., Law, Christopher J., Allman, Sarah A., Tucker, James H. R., Hall, James P. and Vyle, Joseph S. (2019) Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography. Chemical Science, 10 (47). pp. 10948-10957. ISSN 1478-6524 doi:

Howse, G. L., Bovill, R. A., Stephens, P. J. and Osborn, Helen M. I. (2019) Synthesis and antibacterial profiles of targeted triclosan derivatives. European Journal of Medicinal Chemistry, 162. pp. 51-58. ISSN 0223-5234 doi:

Khater, Mai, Ravishankar, Divyashree, Greco, Francesca and Osborn, Helen (2019) Metal complexes of flavonoids: their synthesis, characterization, and enhanced anti-oxidant and anti-cancer activities. Future Medicinal Chemistry, 11 (21). ISSN 1756-8927 doi:

McQuaid, Kane, Hall, James P., Baumgaertner, Lena, Cardin, David J. and Cardin, Christine J. (2019) Three thymine/adenine binding modes of the ruthenium complex Λ-[Ru (TAP)2(dppz)]2+ to the G-quadruplex forming sequence d(TAGGGTT) shown by X-ray crystallography. Chemical Communications, 55. pp. 9116-9119. ISSN 1359-7345 doi:

McQuaid, Kane, Abell, Holly, Gurung, Sarah P., Allan, David R., Winter, Graeme, Sorensen, Thomas, Cardin, David J., Brazier, John A., Cardin, Christine J. and Hall, James P. (2019) Structural studies reveal the enantiospecific recognition of a DNA G-quadruplex by a ruthenium polypyridyl complex. Angewandte Chemie International Edition, 58 (29). pp. 9881-9885. ISSN 1433-7851 doi:

Strohfeldt, Katja (2019) The power of the virtual client – using problem-based learning as a tool for integration in a pharmaceutical sciences laboratory course. Higher Education Pedagogies, 4 (1). pp. 462-475. ISSN 2375-2696 doi:

Vallance, Thomas M., Ravishankar, Divyashree, Albadawi, Dina A. I., Osborn, Helen M. I. and Vaiyapuri, Sakthivel (2019) Synthetic flavonoids as novel modulators of platelet function and thrombosis. International Journal of Molecular Sciences, 20 (12). e3106. ISSN 1422-0067 doi:


Bootman, Martin D., Allman, Sarah, Rietdorf, Katja and Bultynck, Geert (2018) Deleterious effects of calcium indicators within cells: an inconvenient truth. Cell Calcium, 73. pp. 82-87. ISSN 0143-4160 doi:

Brown, Geoffrey D., Bauer, Julia, Osborn, Helen M. I. and Kuemmerle, Rainer (2018) A solution NMR approach to determine the chemical structures of carbohydrates using the hydroxyl groups as starting points. ACS Omega, 3 (12). pp. 17957-17975. ISSN 2470-1343 doi:

Murray, Claire A., Zhu, Zhixue, Cardin, Christine J., Colquhoun, Howard M. and Greenland, Barnaby W. (2018) Quadruple stacking of macrocyclic viologen radical-cations. Supramolecular Chemistry, 30 (9). pp. 751-757. ISSN 1061-0278 doi:

Parker, Matthew P., Murray, Claire A., Hart, Lewis R., Greenland, Barny W., Hayes, Wayne, Cardin, Christine J. and Colquhoun, Howard M. (2018) Mutual complexation between π-π stacked molecular tweezers. Crystal Growth and Design, 18 (1). pp. 386-392. ISSN 1528-7505 doi:

Stachulski, Andrew V., Santoro, M. Gabriella, Piacentini, Sara, Belardo, Giuseppe, La Frazia, Simone, Pidathala, Chandrakala, Row, Eleanor C., Berry, Neil G., Iqbal, Mazhar, Allman, Sarah A., Semple, J.Edward, Eklov, Brian M., O'Neill, Paul M. and Rossignol, Jean-Francois (2018) Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus. Future Medicinal Chemistry, 10 (8). pp. 851-862. ISSN 1756-8927 doi:


Hall, James P., Gurung, Sarah P., Henle, Jessica, Poidl, Patrick, Andersson, Johanna, Lincoln, Per, Winter, Graeme, Sorensen, Thomas, Cardin, David J., Brazier, John A. and Cardin, Christine J. (2017) Guanine can direct binding specificity of Ru-dppz complexes to DNA through steric effects. Chemistry: A European Journal, 23 (21). pp. 4981-4985. ISSN 0947-6539 doi:

Hart, Lewis R., Hayes, Wayne and Greenland, Barnaby W. (2017) Polymeric materials based on NDI and its congeners. In: Pantos, G. Dan (ed.) Naphthalenediimide and its Congeners: From Molecules to Materials. Monographs in Supramolecular Chemistry. Royal Society of Chemistry, London, pp. 167-217. ISBN 9781849739221 doi:

Natfji, Az Alddien, Osborn, Helen M. I. and Greco, Francesca (2017) Feasibility of polymer-drug conjugates for non-cancer applications. Current Opinion in Colloid & Interface Science, 31. pp. 51-66. ISSN 1359-0294 doi:

Natfji, Az Alddien, Ravishankar, Divyashree, Osborn, Helen M. I. and Greco, Francesca (2017) Parameters affecting the enhanced permeability and retention effect: the need for patient selection. Journal of Pharmaceutical Sciences, 106 (11). pp. 3179-3187. ISSN 0022-3549 doi:

Ravishankar, Divyashree, Salamah, Maryam, Attina, Alda, Pothi, Radhika, Vallance, Thomas M., Javed, Muhammad, Williams, Harry F., Alzahrani, Eman M. S., Kabova, Elena, Vaiyapuri, Rajendran, Shankland, Kenneth, Gibbins, Jonathan, Strohfeldt, Katja, Greco, Francesca, Osborn, Helen M. I. and Vaiyapuri, Sakthivel (2017) Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy. Scientific Reports, 7. 5738. ISSN 2045-2322 doi:

Takahashi, Shuntaro, Brazier, John A. and Sugimoto, Naoki (2017) Topological impact of noncanonical DNA structures on Klenow fragment of DNA polymerase. Proceedings of the National Academy of Sciences of the United States of America, 114 (36). pp. 9605-9610. ISSN 0027-8424 doi:

Thomson, Rebecca I., Gardner, Richard A., Strohfeldt, Katja, Fernandes, Daryl L., Stafford, Graham P., Spencer, Daniel I. R. and Osborn, Helen M. I. (2017) Analysis of three epoetin alpha products by LC and LC-MS indicates differences in glycosylation critical quality attributes, including sialic acid content. Analytical Chemistry, 89 (12). pp. 6455-6462. ISSN 0003-2700 doi:


Al-Ani, Widad, Shankland, Kenneth and Cobb, Andre J. A. (2016) Asymmetric organocatalytic synthesis of cyclopentane γ-nitroketones. Synlett, 27 (1). pp. 17-20. ISSN 0936-5214 doi:

Bovill, Richard, Evans, P. G., Howse, G. L. and Osborn, Helen M. I. (2016) Synthesis and biological analysis of novel glycoside derivatives of L-AEP, as targeted antibacterial agents. Bioorganic & Medicinal Chemistry Letters, 26 (15). pp. 3774-3779. ISSN 0960-894X doi:

Bryant, Laura A., Fanelli, Rossana and Cobb, Alexander J. A. (2016) Cupreines and cupreidines: an established class of bifunctional cinchona organocatalysts. Beilstein Journal of Organic Chemistry, 12. pp. 429-443. ISSN 1860-5397 doi:

Chen, Long, Willcock, Helen, Wedge, Christopher J., Hartl, Frantisek, Colquhoun, Howard M. and Greenland, Barny W. (2016) Efficient access to conjugated 4,4’-bipyridinium oligomers using the Zincke reaction: synthesis, spectroscopic and electrochemical properties. Organic and Biomolecular Chemistry, 14 (3). pp. 980-988. ISSN 1477-0520 doi:

Hall, James P., Keane, Paraic M., Beer, Hanna, Buchner, Katrin, Winter, Graeme, Sorensen, Thomas L., Cardin, David J., Brazier, John A. and Cardin, Christine J. (2016) Delta chirality ruthenium ‘light-switch’ complexes can bind in the minor groove of DNA with five different binding modes. Nucleic Acids Research, 44 (19). pp. 9472-9482. ISSN 1362-4962 doi:

Heath, Felicity, Newman, Amy, Clementi, Chiara, Pasut, Gianfranco, Lin, Hong, Stephens, Gary J., Whalley, Ben J., Osborn, Helen M. I. and Greco, Francesca (2016) A novel PEG–haloperidol conjugate with a non-degradable linker shows the feasibility of using polymer–drug conjugates in a non-prodrug fashion. Polymer Chemistry, 7 (47). pp. 7204-7210. ISSN 1759-9954 doi:

Keane, Paraic M., Baptista, Frederico R., Gurung, Sarah P., Devereux, Stephen J., Sazanovich, Igor V., Towrie, Michaal, Brazier, John A., Cardin, Christine J., Kelly, John M. and Quinn, Susan J. (2016) Long-lived excited-state dynamics of i-motif structures probed by time-resolved infrared spectroscopy. ChemPhysChem, 17 (9). pp. 1281-1287. ISSN 1439-7641 doi:

Parshotam, Jay P., Brazier, John A., Bovill, Richard and Osborn, Helen M. I. (2016) An efficient and rapid microwave-assisted synthesis of 1-acetyl-1H-indol-3-YL acetates. Current Microwave Chemistry, 3 (3). pp. 247-257. ISSN 2213-3364 doi:

Ravishankar, Divyashree, Corona, Giulia, Hogan, Stephanie M., Spencer, Jeremy P. E., Greco, Francesca and Osborn, Helen M. I. (2016) Thioflavones as novel neuroprotective agents. Bioorganic & Medicinal Chemistry, 24 (21). pp. 5513-5520. ISSN 0968-0896 doi:

Ravishankar, Divyashree, Watson, Kim A., Greco, Francesca and Osborn, Helen M. I. (2016) Novel synthesised flavone derivatives provide significant insight into the structural features required for enhanced anti-proliferative activity. RSC Advances, 6 (69). pp. 64544-64556. ISSN 2046-2069 doi:

Sinclair, Fern, Chen, Long, Greenland, Barnaby W. and Shaver, Michael P. (2016) Installing multiple functional groups on biodegradable polyesters via post-polymerization olefin cross-metathesis. Macromolecules, 49 (18). pp. 6826-6834. ISSN 0024-9297 doi:


Aitken, Lewis S., Hammond, Lisa E., Sundaram, Rajkumar, Shankland, Kenneth, Brown, Geoffrey D. and Cobb, Andre J. A. (2015) Asymmetric cyclopropanation of conjugated cyanosulfones using a novel cupreine organocatalyst: rapid access to d3-amino acids. Chemical Communications, 51 (70). pp. 13558-13561. ISSN 1359-7345 doi:

Bauer, Julia and Osborn, Helen M. I. (2015) Sialic acids in biological and therapeutic processes: opportunities and challenges. Future Medicinal Chemistry, 7 (16). pp. 2285-2299. ISSN 1756-8927 doi:

Gadd, Adam J. R., Greco, Francesca, Cobb, Alexander J. A. and Edwards, Alexander D. (2015) Targeted activation of toll-like receptors: conjugation of a toll-like receptor 7 agonist to a monoclonal antibody maintains antigen binding and specificity. Bioconjugate Chemistry, 26 (8). pp. 1743-1752. ISSN 1043-1802 doi:

Greenland, Barny W. and Hayes, Wayne (2015) Donor-acceptor π−π stacking interactions: from small molecule complexes to healable supramolecular polymer networks. In: Supramolecular polymer networks and gels. Advances in Polymer Science. Springer, pp. 143-166.

Gurung, Sarah P., Schwarz, Christine, Hall, James P., Cardin, Christine J. and Brazier, John A. (2015) The importance of loop length on the stability of i-motif structures. Chemical Communications, 51 (26). pp. 5630-5632. ISSN 1359-7345 doi:

Hall, James P., Poynton, Fergus E., Keane, Paraic M., Gurung, Sarah P., Brazier, John A., Cardin, David J., Winter, Graeme, Gunnlaugsson, Thorfinnur, Sazanovich, Igor V., Towrie, Michael, Cardin, Christine J., Kelly, John M. and Quinn, Susan J. (2015) Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy. Nature Chemistry, 7. pp. 961-967. ISSN 1755-4330 doi:

Kikuta, Kenji, Piao, Haishun, Brazier, John, Taniguchi, Yosuke, Onizuka, Kazumitsu, Nagatsugi, Fumi and Sasaki, Shigeki (2015) Stabilization of the i-motif structure by the intra-strand cross-link formation. Bioorganic & Medicinal Chemistry Letters, 25 (16). pp. 3307-3310. ISSN 0960-894X doi:

MacDonald, J. P., Parker, M. P., Greenland, B. W., Hermida-Merino, D., Hamley, I. W. and Shaver, M. P. (2015) Tuning thermal properties and microphase separation in aliphatic polyester ABA copolymers. Polymer Chemistry, 6 (9). pp. 1445-1453. ISSN 1759-9954 doi:

Olorunniji, Femi J., McPherson, Arlene L., Pavlou, Hania J., McIlwraith, Michael J., Brazier, John, Cosstick, Richard and Stark, W. Marshall (2015) Nicked-site substrates for a serine recombinase reveal enzyme–DNA communications and an essential tethering role of covalent enzyme–DNA linkages. Nucleic Acids Research, 43 (12). pp. 6134-6143. ISSN 1362-4962 doi:

Ravishankar, Divyashree, Watson, Kimberly A., Boateng, Samuel Y., Green, Rebecca J., Greco, Francesca and Osborn, Helen M.I. (2015) Exploring quercetin and luteolin derivatives as antiangiogenic agents. European Journal of Medicinal Chemistry, 97. pp. 259-274. ISSN 0223-5234 doi:

Strohfeldt, Katja and Khutoryanskaya, Olga (2015) Using problem-based learning in a chemistry practical class for pharmacy students and engaging them with feedback. American Journal of Pharmaceutical Education, 79 (9). 141. ISSN 1553-6467 doi:


Dell'Isola, Antonio, McLachlan, Matthew M. W., Neuman, Benjamin W., Al-Mullah, Hawaa M. N., Binks, Alexander W. D., Elvidge, Warren, Shankland, Kenneth and Cobb, Alexander J. A. (2014) Synthesis and antiviral properties of spirocyclic [1,2,3]-triazolooxazine nucleosides. Chemistry- A European Journal, 20 (37). pp. 11685-11689. ISSN 0947-6539 doi:

Hart, Lewis R., Hunter, James H, Nguyen, Ngoc A, Harries, Josephine L, Greenland, Barnaby W., Mackay, Michael E, Colquhoun, Howard M. and Hayes, Wayne (2014) Multivalency in healable supramolecular polymers: the effect of supramolecular cross-link density on the mechanical properties and healing of noncovalent polymer networks. Polymer Chemistry, 5 (11). pp. 3680-3688. ISSN 1759-9954 doi:

Harvey, David J., Edgeworth, Matthew, Krishna, Benjamin A., Bonomelli, Camille, Allman, Sarah A., Crispin, Max and Scrivens, James H. (2014) Fragmentation of negative ions from N-linked carbohydrates: Part 6. Glycans containing oneN-acetylglucosamine in the core. Rapid Communications in Mass Spectrometry, 28 (18). pp. 2008-2018. ISSN 0951-4198 doi:

Rajora, Amit K., Ravishankar, Divyashree, Osborn, Helen M.I. and Greco, Francesca (2014) Impact of the enhanced permeability and retention (EPR) effect and cathepsins levels on the activity of polymer-drug conjugates. Polymers, 6 (8). pp. 2186-2220. ISSN 2073-4360 doi:

Steinke, Joachim H. G., Greenland, Barnaby W., Johns, Stephen, Parker, Matthew P., Atkinson, Robert C. J., Cade, Ian A. and Trussell, Stephen J. (2014) Robust and operationally simple synthesis of Poly(bis(2,2,2- trifluoroethoxy) phosphazene) with controlled molecular weight, low PDI, and high conversion. ACS Macro Letters, 3. pp. 548-551. ISSN 2161-1653 doi:

Vaiyapuri, Rajendran, Greenland, Barnaby, Colquhoun, Howard M., Elliott, Joanne M. and Hayes, Wayne (2014) Evolution of supramolecular healable composites: a minireview. Polymer International, 63 (6). pp. 933-942. ISSN 0959-8103 doi:


Alonzi, D. S., Kukushkin, N. V., Allman, S. A., Hakki, Z., Williams, S. J., Pierce, L., Dwek, R. A. and Butters, T. D. (2013) Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins. Cellular and Molecular Life Sciences, 70 (15). pp. 2799-2814. ISSN 1420-682X doi:

Bajaj, N., Hart, L. R., Greenland, B. W. and Hayes, Wayne (2013) Urea organogelators: synthesis and properties. Macromolecular Symposia, 329 (1). pp. 118-124. ISSN 1022-1360 doi:

Cheng, Ge, Greenland, Barnaby W., Lampard, Chris, Williams, Neal, Bahra, Malkit S. and Hayes, Wayne (2013) Lightly branched comb polyesters: application in fast drying solvent-borne coating formulations. Reactive & Functional Polymers, 73 (4). pp. 619-623. ISSN 1381-5148 doi:

Cheng, Ge, Greenland, Barnaby W., Lampard, Chris, Williams, Neil, Barhra, Malkit S. and Hayes, Wayne (2013) Synthesis of novel hyperbranched polymers featuring oxazoline linear units and their application in fast-drying solvent-borne coating formulations. Journal of Polymer Science Part A: Polymer Chemistry, 51 (18). pp. 3964-3974. ISSN 1099-0518 doi:

Cobb, Andre, Arezki, Natasha, Dell'Isola, Antonio and Aitken, Lewis (2013) Asymmetric organocatalysis and the nitro group functionality. Synthesis-Stuttgart, 45 (19). pp. 2627-2648. ISSN 0039-7881 doi:

Greenland, Barnaby W and Hayes, Wayne (2013) Healable polymeric materials. In: Greenland, Barnaby W and Hayes, Wayne (eds.) Healable polymer systems. Royal Society of Chemistry, London, pp. 1-15. ISBN 9781849736268 doi:

Greenland, Barnaby W., Bird, Matthew B., Burattini, Stefano, Cramer, Rainer, O'Reilly, Rachel K., Patterson, Joseph P., Hayes, Wayne, Cardin, Christine J. and Colquhoun, Howard M. (2013) Mutual binding of polymer end-groups by complementary π–π-stacking: a molecular “Roman Handshake”. Chemical Communications, 49 (5). pp. 454-456. ISSN 1359-7345 doi:

Greenland, Barnaby W., Fiore, Gina L., Rowan, Stuart J. and Weder, Christoph (2013) Healable supramolecular polymeric materials. In: Hayes, Wayne and Greenland, Barnaby W. (eds.) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp. 92-125. ISBN 9781849736268 doi:

Hart, Lewis R., Harries, J. L., Greenland, Barnaby W., Colquhoun, Howard M. and Hayes, Wayne (2013) Healable supramolecular polymers. Polymer Chemistry, 4. pp. 4860-4870. ISSN 1759-9954 doi:

Hayes, Wayne and Greenland, Barnaby W., eds. (2013) Healable Polymer Systems. Royal Society of Chemistry, Cambridge, pp165. ISBN 9781849736268

Jarvis, Ashley N., McClaren, Andrew B., Osborn, Helen M. I. and Sweeney, Joseph (2013) Preparation and ring-opening reactions of N-diphenylphosphinyl vinyl aziridines. Beilstein Journal of Organic Chemistry, 9. pp. 852-859. ISSN 1860-5397 doi:

Murray, Claire A., Cardin, Christine J., Greenland, Barny W., Swift, Andrew and Colquhoun, Howard M. (2013) Pairwise assembly of organopalladium(II) units with cyanurato(3-) and trithiocyanurato(3-) ligands: formation of chiral Pd12, Pd10 and Pd9 cage-molecules. Inorganic Chemistry, 52 (18). pp. 10424-10430. ISSN 0020-1669 doi:

Rajkumar, Sundaram, Shankland, Kenneth, Goodman, Jonathan M. and Cobb, Alexander J.A. (2013) Organocatalytic domino reaction of cyanosulfones: access to complex cyclohexane systems with quaternary carbon centers. Organic Letters, 15 (6). pp. 1386-1389. ISSN 1523-7060 doi:

Ravishankar, Divya, Rajora, Amit, Greco, Francesca and Osborn, Helen (2013) Flavonoids as prospective compounds for anti-cancer therapy. International Journal of Biochemistry and Cell Biology, 45 (12). pp. 2821-2831. ISSN 1878-5875 doi:

Vaiyapuri, Rajendran, Greenland, Barnaby W, Colquhoun, Howard M, Elliott, Joanne E and Hayes, Wayne (2013) Molecular recognition between functionalized gold nanoparticles and healable, supramolecular polymer blends – a route to property enhancement. Polymer Chemistry, 4. pp. 4902-4909. ISSN 1759-9954 doi:


Brazier, John A., Shah, Arti and Brown, Geoffrey D. (2012) I-Motif formation in gene promoters: unusually stable formation in sequences complementary to known G-quadruplexes. Chemical Communication, 48 (87). pp. 10739-10741. ISSN 1359-7345 doi:

Rajkumar, S., Shankland, Kenneth, Brown, Geoffrey D. and Cobb, Andre (2012) Organocatalytic enantioselective construction of nitrocyclohexanes containing multiple chiral centres via a cascade reaction. Chemical Science, 3. pp. 584-588. ISSN 1478-6524 doi:

Rangam, Gopinath, Schmitz, Kerstin-Maike, Cobb, Andre and Petersen-Mahrt, Svend (2012) AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud. PloS ONE, 7 (8). e43279. ISSN 1932-6203 doi:

Shaikh, Abdul K., Cobb, Andre J A and Varvounis, George (2012) Mild and rapid method for the generation of ortho-(naphtho)-quinone methide intermediates. Organic Letters, 14 (2). pp. 584-587. ISSN 1523-7060 doi:


Benning, R. K., Osborn, Helen Mary Isted and Turkson, Andrea (2011) Regioselective Beckmann rearrangements of furanoside and pyranoside-derived oximes. Tetrahedron: Asymmetry, 22 (1). pp. 109-116. ISSN 0957-4166 doi:

Burland, Peter A., Osborn, Helen M. I. and Turkson, Andrea (2011) Synthesis and glycosidase inhibitory profiles of functionalised morpholines and oxazepanes. Bioorganic & Medicinal Chemistry, 19 (18). pp. 5679-5692. ISSN 0968-0896 doi:

Cobb, Andre (2011) General aspects of organocatalytic cyclizations. In: Mahrwald, Rainer (ed.) Enantioselective Organocatalyzed Reactions II: Asymmetric C-C Bond Formation Processes. Springer, pp. 1-40. ISBN 9789048138661

Fais, M., Karamanska, R., Allman, Sarah, Fairhurst, S. A., Innocenti, P., Fairbanks, A. J., Donohoe, T. J., Davis, B. G., Russell, D. A. and Field, R. A (2011) Surface plasmon resonance imaging of glycoarrays identifies novel and unnatural carbohydrate-based ligands for potential ricin sensor development. Chemical Science, 2 (10). pp. 1952-1959. ISSN 2041-6539 doi:

Fante, Cristina, Eldar-Boock, Anat, Satchi-Fainaro, Ronit, Osborn, Helen M. I. and Greco, Francesca (2011) Synthesis and biological evaluation of a polyglutamic acid-dopamine conjugate: a new antiangiogenic agent. Journal of Medicinal Chemistry, 54 (14). pp. 5255-5259. ISSN 0022-2623 doi:

Fern, S. E., Heath, Peter and Cobb, Alexander John Andre (2011) Aldol reaction of butane-2,3-diacetal protected methyl glycerate. Tetrahedron: Asymmetry, 22 (2). pp. 149-152. ISSN 0957-4166 doi:

Rassmussen, T. S., Allman, Sarah, Twigg, G., Butters, T. D. and Jensen, H. H. (2011) Synthesis of N-alkylated noeurostegines and evaluation of their potential as treatment for Gaucher's disease. Bioorganic & Medicinal Chemistry Letters, 21 (5). pp. 1519-1522. ISSN 0960-894X doi:

Sarsam, Susan W., Nutt, David R., Strohfeldt, Katja and Watson, Kimberly A. (2011) Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study. Metallomics, 3 (2). pp. 152-161. ISSN 1756-5901 doi:

Stachulski, A. V., Pidathala, C., Row, E. C., Sharma, R., Berry, N. G., Lawrenson, A. S., Moores, S. L, Iqbal, M., Bentley, J., Allman, S., Edwards, G., Helm, A., Hellier, J., Korba, B. E., Semple, J. E. and Rossignol, J.-F. (2011) Thiazolides as novel antiviral agents. 2. Inhibition of hepatitis C virus replication. Journal of Medicinal Chemistry, 54 (24). pp. 8670-8680. ISSN 0022-2623 doi:

Stachulski, A.V., Pidathala, C., Row, E.C., Sharma, R., Berry, N.G., Iqbal, M., Bentley, J., Allman, S.A., Edwards, G., Helm, A., Hellier, J., Korba, B.E., Semple, J.E. and Rossignol, Jean-Francois (2011) Thiazolides as novel antiviral agents. 1. Inhibition of hepatitis B virus replication. Journal of Medicinal Chemistry, 54 (12). pp. 4119-4132. ISSN 0022-2623 doi:


Bauer, JO, Stiller, J, Marques-Lopez, E, Strohfeldt, Katja Astrid, Christmann, M and Strohmann , C (2010) Silyl-Modified Analogues of 2-Tritylpyrrolidine: Synthesis and Applications in Asymmetric Organocatalysis. Chemistry - A European Journal, 16 (42). pp. 12553-12558. ISSN 0947-6539 doi:

Burland, P. A., Coisson, D. and Osborn, Helen Mary Isted (2010) Rapid synthesis of carbohydrate derivatives, including mimetics of c-linked disaccharides and c-Linked aza disaccharides, using the Hetero-Diels−Alder Reaction. Journal of Organic Chemistry, 75 (21). pp. 7210-7218. ISSN 0022-3263 doi:

Carlescu, Irina, Osborn, Helen M.I., Desbrieres, Jacques, Scutaru, Dan and Popa, Marcel (2010) Synthesis of poly(aspartimide)-based bio-glycoconjugates. Carbohydrate Research, 345 (1). pp. 33-40. ISSN 0008-6215 doi:

Kolstoe, S. E., Mangione, P. P., Bellotti, V., Taylor, G. W., Tennent, G. A., Deroo, S., Morrison, A. J., Cobb, Alexander John Andre, Coyne, A., McCammon, M. G., Warner, T. D., Mitchell, J., Gill, R., Smith, M. D., Ley, S. V., Robinson, S. P. and Pepys, M. B. (2010) Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proceedings of the National Academy of Sciences of the United States of America, 107 (47). pp. 20483-20488. ISSN 0027-8424 doi:

Nodes, William J., Shankland, Kenneth, Rajkumar, Sundaram and Cobb, Alexander John Andre (2010) Asymmetric phase-transfer-catalyzed synthesis of five-membered cyclic gamma-Amino acid precursors. Synlett, 2010 (20). pp. 3011-3014. ISSN 1437-2096 doi:

Strohfeldt, Katja and Grant, Daniel T. (2010) A model for self-directed problem-based learning for renal therapeutics. American Journal of Pharmaceutical Education , 74 (9). Article 173.


Allman, S. A., Jensen, H. H., Vijayakrishnan, B., Garnett, J. A., Leon, E., Liu, Y., Anthony, D. C., Sibson, N. R., Feizi, T., Matthews, S. and Davis, B. G. (2009) Potent fluoro-oligosaccharide probes of adhesion in Toxoplasmosis. ChemBioChem, 10 (15). pp. 2522-2529. ISSN 1439-7633 doi:

Garnett, James A., Liu, Yan, Leon, Ester, Allman, Sarah A., Friedrich, Nikolas, Saouros, Savvas, Curry, Stephen, Soldati-Favre, Dominique, Davis, Benjamin G., Feizi, Ten and Matthews, Stephen (2009) Detailed insights from microarray and crystallographic studies into carbohydrate recognition by microneme protein 1 (MIC1) of Toxoplasma gondii. Protein Science, 18 (9). pp. 1935-1947. ISSN 0961-8368 doi:

Jawaid, Samaila, Khan, Tariq H., Osborn, Helen M. I. and Williams, Nana O. A. (2009) Tyrosinase activated melanoma prodrugs. Anti-cancer agents in medicinal chemistry, 9 (7). pp. 717-727. ISSN 1871-5206

Nodes, William, Nutt, David Richard, Chippindale, Ann Mary and Cobb, Alexander John Andre (2009) Enantioselective Intramolecular Michael Addition of Nitronates onto Conjugated Esters: Access to Cyclic γ-Amino Acids with up to Three Stereocenters. Journal of the American Chemical Society, 131 (44). pp. 16016-16017. ISSN 0002-7863 doi:

Osborn, Helen M. I. and Turkson, Andrea (2009) Synthesis and NMR spectroscopic analysis of 3-nitro-pyranoside, 3-nitro-septanoside and 4-nitro-septanoside derivatives by condensation of the anion of nitromethane with glycoside. Tetrahedron Asymmetry, 20 (18). pp. 2162-2166. ISSN 0957-4166 doi:

Vessieres, Anne, Plamont, Marie-Aude, Cabestaing, Claude, Claffey, James, Dieckmann, Sandra, Hogan, Megan, Mueller-Bunz, Helge, Strohfeldt, Katja Astrid and Tacke, Matthias (2009) Proliferative and anti-proliferative effects of titanium- and iron-based metallocene anti-cancer drugs. Journal of Organometallic Chemistry , 694 (6). pp. 874-879. ISSN 0022-328X doi:


Baksh, Mohamed Fazilluddeen and Kelly, Patrick (2008) Statistical methods for examining genetic influences of resistance to anti-epileptic drugs. Expert Review of Clinical Pharmacology, 1 (1). pp. 137-144. ISSN 1751-2433 doi:

Bonjoch, Josep, Drew, Michael G.B., Gonzalez, Asensio, Greco, Francesca, Jawaid, Samaila, Osborn, Helen Mary Isted, Williams, Nana A.O. and Yaqoob, Parveen (2008) Synthesis and evaluation of novel boron-containing complexes of potential use for the selective treatment of malignant melanoma. Journal of Medicinal Chemistry, 51 (20). pp. 6604-6608. ISSN 0022-2623 doi:

Ellis, David, Norman, Sarah Ellen and Osborn, Helen Mary Isted (2008) Synthesis of S-linked carbohydrate analogues via a Ferrier reaction. Tetrahedron, 64 (12). pp. 2832-2854. ISSN 0040-4020 doi:

Strohfeldt, Katja Astrid and Tacke, Matthias (2008) Bioorganometallic fulvene-derived titanocene anti-cancer drugs. Chemical Society Reviews, 37 (6). pp. 1174-1187. ISSN 0306-0012 doi:


Campo, Vanessa Leiria, Carvalho, Ivone, Allman, Sarah, Davis, Benjamin G. and Field, Robert A. (2007) Chemical and chemoenzymatic synthesis of glycosyl-amino acids and glycopeptides related to Trypanosoma cruzi mucins. Organic & Biomolecular Chemistry, 5 (16). pp. 2645-2657. ISSN 1477-0520 doi:

Gaynor, J. W., Brazier, John and Cosstick, R. (2007) Synthesis of 3 '-S-phosphorothiolate oligonucleotides for their potential use in RNA interference. Nucleosides Nucleotides & Nucleic Acids, 26 (6-7). pp. 709-712. ISSN 1525-7770 doi:


Brazier, J. A., Shibata, T., Townsley, J., Taylor, B. F., Frary, E., Williams, N. H. and Williams, D. M. (2005) Amino-functionalized DNA: the properties of C5-amino-alkyl substituted 2′-deoxyuridines and their application in DNA triplex formation. Nucleic Acids Research, 33 (4). pp. 1362-1371. ISSN 1362-4962 doi:

This list was generated on Mon Dec 4 21:25:19 2023 UTC.

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