Accessibility navigation


Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study

Gulseth, H. L., Gjelstad, I. M.F., Tierney, A. C., Shaw, D. I., Helal, O., van Hees, A. M.J., Delgado-Lista, J., Leszczynska-Golabek, I., Karlström, B., Lovegrove, J. A., Defoort, C., Blaak, E. E., Lopez-Miranda, J., Dembinska-Kiec, A., Risérus, U., Roche, H. M., Birkeland, K. I., and Drevon, C. A. (2010) Dietary fat modifications and blood pressure in subjects with the metabolic syndrome in the LIPGENE dietary intervention study. British Journal of Nutrition, 104 (2). pp. 160-163. ISSN 1475-2662

Full text not archived in this repository.

To link to this article DOI: 10.1017/S0007114510000565

Abstract/Summary

Hypertension is a key feature of the metabolic syndrome. Lifestyle and dietary changes may affect blood pressure (BP), but the knowledge of the effects of dietary fat modification in subjects with the metabolic syndrome is limited. The objective of the present study was to investigate the effect of an isoenergetic change in the quantity and quality of dietary fat on BP in subjects with the metabolic syndrome. In a 12-week European multi-centre, parallel, randomised controlled dietary intervention trial (LIPGENE), 486 subjects were assigned to one of the four diets distinct in fat quantity and quality: two high-fat diets rich in saturated fat or monounsaturated fat and two low-fat, high-complex carbohydrate diets with or without 1·2 g/d of very long-chain n-3 PUFA supplementation. There were no overall differences in systolic BP (SBP), diastolic BP or pulse pressure (PP) between the dietary groups after the intervention. The high-fat diet rich in saturated fat had minor unfavourable effects on SBP and PP in males.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
ID Code:16369
Publisher:Cambridge University Press

Centaur Editors: Update this record

Page navigation