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Therapygenetics: the 5HTTLPR and response to psychological therapy

Eley, T. C., Hudson, J. L., Creswell, C., Tropeano, M., Lester, K. J., Cooper, P., Farmer, A., Lewis, C. M., Lyneham, H. J., Rapee, R. M., Uher, R., Zavos, H. M. S. and Collier, D. A. (2012) Therapygenetics: the 5HTTLPR and response to psychological therapy. Molecular Psychiatry, 17. pp. 236-237. ISSN 1476-5578

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To link to this article DOI: 10.1038/mp.2011.132

Abstract/Summary

Although pharmacogenetic research thrives,1 genetic determinants of response to purely psychotherapeutic treatments remain unexplored. In a sample of children undergoing cognitive behaviour therapy (CBT) for an anxiety disorder, we tested whether treatment response is associated with the serotonin transporter gene promoter region (5HTTLPR), previously shown to moderate environmental influences on depression.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Winnicott
Faculty of Life Sciences > School of Psychology and Clinical Language Sciences > Psychopathology and Affective Neuroscience
Faculty of Life Sciences > School of Psychology and Clinical Language Sciences > Department of Psychology
ID Code:25482
Publisher:Nature Publishing Group

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