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Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D

Berry, D. J., Vimaleswaran, K. S., Whittaker, J. C., Hingorani, A. D. and Hyppönen, E. (2012) Evaluation of genetic markers as instruments for Mendelian randomization studies on vitamin D. PLoS ONE, 7 (5). e37465. ISSN 1932-6203

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Abstract/Summary

Combining SNPs into allele scores provides a more powerful instrument for MR analysis than a single SNP in isolation. Population stratification and the potential for pleiotropic effects need to be considered in MR studies on vitamin D.

Item Type:Article
Refereed:Yes
Divisions:Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
ID Code:34646
Publisher:Public Library of Science

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