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Items where Author is "Clerk, Professor Angela"

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Sugden, P. H., McGuffin, L. J. and Clerk, A. (2013) SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein–protein interactions. Biochemical Journal, 454 (1). pp. 13-30. ISSN 0264-6021 doi: 10.1042/BJ20130219

Barrett, O. P. T., Yndestad, A., Marshall, A. K., Sugden, P. H. and Clerk, A. (2013) The early transcriptomic response to interleukin 1β and interleukin 33 in rat neonatal cardiomyocytes. Cytokine, 61 (2). pp. 340-344. ISSN 1096-0023 doi: 10.1016/j.cyto.2012.11.004

Amirak, E., Fuller, S. J., Sugden, P. H. and Clerk, A. (2013) p90 ribosomal S6 kinases play a significant role in early gene regulation in the cardiomyocyte response to Gq protein-coupled receptor stimuli, endothelin-1 and α1-adrenergic receptor agonists. Biochemical Journal, 450. pp. 351-363. ISSN 0264-6021 doi: 10.1042/BJ20121371 (In Press)

Giraldo, A., Barrett, O., Tindall, M., Fuller, S., Amirak, E., Bhattacharya, B., Sugden, P. and Clerk, A. (2012) Feedback regulation by Atf3 in the endothelin-1-responsive transcriptome of cardiomyocytes: Egr1 is a principal Atf3 target. Biochemical Journal, 444 (2). pp. 343-355. ISSN 0264-6021 doi: 10.1042/BJ20120125

Fuller, S. J., McGuffin, L. J., Marshall, A. K., Giraldo, A., Pikkarainen, S., Clerk, A. and Sugden, P. (2012) A novel, non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3). Biochemical Journal, 442 (3). pp. 595-610. ISSN 0264-6021 doi: 10.1042/BJ20112000

Sugden, P., Markou, T., Fuller, S. J., Tham, E. L., Molkentin, J., Paterson, H. and Clerk, A. (2011) Monophosphothreonyl extracellular signal-regulated kinases 1 and 2 (ERK1/2) are formed endogenously in intact cardiac myocytes and are enzymically active. Cellular Signalling, 23 (2). pp. 468-477. ISSN 0898-6568 doi: 10.1016/j.cellsig.2010.10.024

Marshall, A. K., Barrett, O. P. T., Cullingford, T. E., Shanmugasundram, A., Sugden, P. and Clerk, A. (2010) ERK1/2 signaling dominates over RhoA signaling in regulating early changes in RNA expression induced by endothelin-1 in neonatal rat cardiomyocytes. PLoS ONE, 5 (4). e10027. ISSN 1932-6203 doi: 10.1371/journal.pone.0010027

Yndestad, A., Marshall, A. K., Hodgkinson, J., Tham, E. L., Sugden, P. and Clerk, A. (2010) Modulation of interleukin signalling and gene expression in cardiac myocytes by endothelin-1. International Journal of Biochemistry & Cell Biology, 42 (2). pp. 263-272. ISSN 1357-2725 doi: 10.1016/j.biocel.2009.10.021

Markou, T., Marshall, A. K., Cullingford, T., Tham, E. L., Sugden, P. and Clerk, A. (2010) Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin. BMC Genomics, 11. 343. ISSN 1471-2164 doi: 10.1186/1471-2164-11-343

Clerk, A., Cullingford, T. E., Fuller, S., Giraldo, A. and Sugden, P. (2009) Endothelin-1 regulation of immediate early gene expression in cardiac myocytes: negative feedback regulation of interleukin 6 by Atf3 and Klf2. Advances in Enzyme Regulation, 49 (1). pp. 30-42. ISSN 0065-2571 doi: 10.1016/j.advenzreg.2008.12.007

Pikkarainen, S., Kennedy, R., Marshall, A. K., Tham, E. L., Lay , K., Kriz, T., Handa, B., Clerk, A. and Sugden, P. (2009) Regulation of expression of the rat orthologue of mouse double minute 2 (MDM2) by H2O2-induced oxidative stress in neonatal rat cardiac myocytes. The Journal of Biological Chemistry, 284 (40). pp. 27195-27210. ISSN 1083-351X doi: 10.1074/jbc.M109.037887

Cullingford, T. E., Butler, M. J., Marshall, A. K., Tham, E. L., Sugden, P. H. and Clerk, A. (2008) Differential regulation of Krüppel-like factor family transcription factor expression in neonatal rat cardiac myocytes: effects of endothelin-1, oxidative stress and cytokines. Biochimica Et Biophysica Acta-Molecular Cell Research, 1783 (6). pp. 1229-1236. ISSN 0167-4889 doi: 10.1016/j.bbamcr.2008.03.007

Sugden, P. H., Fuller, S. J., Weiss, S. C. and Clerk, A. (2008) Glycogen synthase kinase 3 (GSK3) in the heart: a point of integration in hypertrophic signalling and a therapeutic target? A critical analysis. British Journal of Pharmacology, 153 (S1). S137-S153. ISSN 1476-5381 doi: 10.1038/sj.bjp.0707659

Prasad, S. K., Clerk, A., Cullingford, T. E., Chen, A. W. Y., Kemp, T. J., Cannell, T. M., Cowie, M. R. and Petrou, M. (2008) Gene expression profiling of human hibernating myocardium: Increased expression of B-type natriuretic peptide and proenkephalin in hypocontractile vs normally-contracting regions of the heart. European Journal of Heart Failure, 10 (12). pp. 1177-1180. ISSN 1388-9842 doi: 10.1016/j.ejheart.2008.08.008

Markou, T., Cullingford, T. E., Giraldo Ramirez, A., Weiss, S. C., Alsafi, A., Fuller, S. J., Clerk, A. and Sugden, P. H. (2008) Glycogen synthase kinases 3α and 3β in cardiac myocytes: regulation and consequences of their inhibition. Cellular Signalling, 20 (1). pp. 206-218. ISSN 0898-6568 doi: 10.1016/j.cellsig.2007.10.004

Fuller, S. J., Pikkarainen, S., Tham, E. L., Cullingford, T. E., Molkentin, J. D., Cornils, H., Hergovitch, A., Hemmings, B. A., Clerk, A. and Sugden, P. H. (2008) Nuclear Dbf2-related protein kinases (NDRs) in isolated cardiac myocytes and the myocardium: activation by cellular stresses and by phosphoprotein serine-/threonine-phosphatase inhibitors. Cellular Signalling, 20 (8). pp. 1564-1577. ISSN 0898-6568 doi: 10.1016/j.cellsig.2008.04.013

Cullingford, T. E., Markou, T., Fuller, S. J., Giraldo Ramirez, A., Pikkarainern, S., Zoumpoulidou, G., Alsafi, A., Ekere, C., Kemp, T. J., Dennis, J. L., Game, L., Sugden, P. and Clerk, A. (2008) Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes. Genome Biology, 9 (2). R32. ISSN 1474-760X doi: 10.1186/gb-2008-9-2-r32

This list was generated on Wed Jul 30 00:00:50 2014 BST.

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