Accessibility navigation


Items where Author is "Hughes, Dr Craig"

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
[tool] Batch List
Group by: Item Type | No Grouping
Number of items: 30.

Article

Hughes, C. E. (2018) How to perform aggregometry and lumi-aggregometry in mouse platelets. Platelets. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2018.1478074

Mangin, P. H., Onselaer, M.-B., Receveur, N., Le Lay, N., Hardy, A. T., Wilson, C., Sanchez, X., Loyau, S., Dupuis, A., Babar, A. K., Miller, J. L. C., Philippou, H., Hughes, C. E., Herr, A. B., Ariens, R. A., Mezzano, D., Jandrot-Perrus, M., Gachet, C. and Watson, S. P. (2018) Immobilized fibrinogen activates human platelets through GPVI. Hematologica, 103 (5). pp. 898-907. ISSN 1592-8721 doi: https://doi.org/10.3324/haematol.2017.182972

Bye, A. P., Unsworth, A. J., Desborough, M. J., Hildyard, C. A. T., Appleby, N., Bruce, D., Kriek, N., Nock, S. H., Sage, T., Hughes, C. E. and Gibbins, J. M. (2017) Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib. Blood Advances, 1 (26). pp. 2610-2623. ISSN 2473-9529 doi: https://doi.org/10.1182/bloodadvances.2017011999

Lombard, S. E., Pollitt, A. Y., Hughes, C. E., Di, Y., Mckinnon, T., O'Callaghan, C. A. and Watson, S. P. (2017) Mouse podoplanin supports adhesion and aggregation of platelets under arterial shear: a novel mechanism of haemostasis. Platelets. ISSN 0953-7104 doi: https://doi.org/10.1080/09537104.2017.1356919

Alshehri, O. M., Hughes, C. E., Montague, S., Watson, S. K., Frampton, J., Bender, M. and Watson, S. P. (2015) Fibrin activates GPVI in human and mouse platelets. Blood, 126 (13). pp. 1601-1608. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2015-04-641654

Alshehri, O. M., Montague, S., Watson, S., Carter, P., Sarker, N., Manne, B. K., Miller, J. L. C., Herr, A. B., Pollitt, A. Y., O'Callaghan, C. A., Kunapuli, S., Arman, M., Hughes, C. E. and Watson, S. P. (2015) Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands. Biochemical Journal, 468 (3). pp. 459-473. ISSN 0264-6021 doi: https://doi.org/10.1042/BJ20150192

Hughes, C. E., Finney, B. A., Koentgen, F., Lowe, K. L. and Watson, S. P. (2015) The N-terminal SH2 domain of Syk is required for (hem)ITAM, but not integrin, signaling in mouse platelets. Blood, 125 (1). pp. 144-154. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-05-579375

Cherpokova, D., Bender, M., Morowski, M., Kraft, P., Schuhmann, M. K., Akbar, S. M., Sultan, C. S., Hughes, C. E., Kleinschnitz, C., Stoll, G., Dragone, L. L., Watson, S. P., Tomlinson, M. G. and Nieswandt, B. (2015) SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice. Blood, 125 (1). pp. 185-194. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2014-06-580597

Pollitt, A. Y., Poulter, N. S., Gitz, E., Navarro-Nuñez, L., Wang, Y.-J., Hughes, C. E., Thomas, S. G., Nieswandt, B., Douglas, M. R., Owen, D. M., Jackson, D. G., Dustin, M. L. and Watson, S. P. (2014) Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells. The Journal of Biological Chemistry, 289 (52). pp. 35695-35710. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M114.584284

Dütting, S., Vögtle, T., Morowski, M., Schiessl, S., Schäfer, C. M., Watson, S. K., Hughes, C. E., Ackermann, J. A., Radtke, D., Hermanns, H. M., Watson, S. P., Nitschke, L. and Nieswandt, B. (2014) Growth factor receptor-bound protein 2 contributes to (hem)immunoreceptor tyrosine-based activation motif-mediated signaling in platelets. Circulation Research, 114 (3). pp. 444-453. ISSN 0009-7330 doi: https://doi.org/10.1161/CIRCRESAHA.114.302670

Manne, B. K., Getz, T. M., Hughes, C. E., Alshehri, O., Dangelmaier, C., Naik, U. P., Watson, S. P. and Kunapuli, S. P. (2013) Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2). The Journal of Biological Chemistry, 288 (11). pp. 7717-7726. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M112.424473

Hughes, C. E., Sinha, U., Pandey, A., Eble, J. A., O'Callaghan, C. A. and Watson, S. P. (2013) Critical role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2). The Journal of Biological Chemistry, 288 (7). pp. 5127-5135. ISSN 1083-351X doi: https://doi.org/10.1074/jbc.M112.411462

Finney, B. A., Schweighoffer, E., Navarro-Núñez, L., Bénézech, C., Barone, F., Hughes, C. E., Langan, S. A., Lowe, K. L., Pollitt, A. Y., Mourao-Sa, D., Sheardown, S., Nash, G. B., Smithers, N., Reis e Sousa, C., Tybulewicz, V. L. J. and Watson, S. P. (2012) CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development. Blood, 119 (7). pp. 1747-1756. ISSN 0006-4971 doi: https://doi.org/10.1182/blood-2011-09-380709

Jarvis, G. E., Bihan, D., Hamaia, S., Pugh, N., Ghevaert, C. J. G., Pearce, A. C., Hughes, C. E., Watson, S. P., Ware, J., Rudd, C. E. and Farndale, R. W. (2012) A role for adhesion and degranulation-promoting adapter protein in collagen-induced platelet activation mediated via integrin α(2) β(1). Journal of Thrombosis and Haemostasis, 10 (2). pp. 268-277. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2011.04567.x

Hughes, C. E., Radhakrishnan, U. P., Lordkipanidzé, M., Egginton, S., Dijkstra, J. M., Jagadeeswaran, P. and Watson, S. P. (2012) G6f-like is an ITAM-containing collagen receptor in thrombocytes. PLoS ONE, 7 (12). e52622. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0052622

Brazón, J., Hughes, C. E., Mori, J., Sevcik, C., D'suze, G. and Watson, S. P. (2011) Tityus discrepans scorpion venom activates platelets through GPVI and a novel Src-dependent signaling pathway. Platelets, 22 (3). pp. 165-172. ISSN 0953-7104 doi: https://doi.org/10.3109/09537104.2010.544343

Hughes, C. E., Navarro-Núñez, L., Finney, B. A., Mourão-Sá, D., Pollitt, A. Y. and Watson, S. P. (2010) CLEC-2 is not required for platelet aggregation at arteriolar shear. Journal of Thrombosis and Haemostasis, 8 (10). pp. 2328-2332. ISSN 1538-7933 doi: https://doi.org/10.1111/j.1538-7836.2010.04006.x

Hughes, C. E., Pollitt, A. Y., Mori, J., Eble, J. A., Tomlinson, M. G., Hartwig, J. H., O'Callaghan, C. A., Fütterer, K. and Watson, S. P. (2010) CLEC-2 activates Syk through dimerization. Blood, 115 (14). pp. 2947-2955. ISSN 1528-0020 doi: https://doi.org/10.1182/blood-2009-08-237834

Spalton, J. C., Mori, J., Pollitt, A. Y., Hughes, C. E., Eble, J. A. and Watson, S. P. (2009) The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC-2 signaling in platelets. Journal of thrombosis and haemostasis : JTH, 7 (7). pp. 1192-9. ISSN 1538-7836

Grygielska, B., Hughes, C. E. and Watson, S. P. (2009) Molecular basis of platelet activation by an alphaIIbbeta3-CHAMPS peptide. Journal of thrombosis and haemostasis : JTH, 7 (2). pp. 339-46. ISSN 1538-7836

Hughes, C. E., Auger, J. M., McGlade, J., Eble, J. A., Pearce, A. C. and Watson, S. P. (2008) Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2. Journal of thrombosis and haemostasis : JTH, 6 (12). pp. 2152-9. ISSN 1538-7836

Riba, R., Hughes, C. E., Graham, A., Watson, S. P. and Naseem, K. M. (2008) Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor gamma chain complex. Journal of thrombosis and haemostasis : JTH, 6 (6). pp. 1012-20. ISSN 1538-7836

Pears, C. J., Thornber, K., Auger, J. M., Hughes, C. E., Grygielska, B., Protty, M. B., Pearce, A. C. and Watson, S. P. (2008) Differential roles of the PKC novel isoforms, PKCδ and PKCε, in mouse and human platelets. PLoS ONE, 3 (11). e3793. ISSN 1932-6203 doi: https://doi.org/10.1371/journal.pone.0003793

Hughan, S. C., Hughes, C. E., McCarty, O. J. T., Schweighoffer, E., Soultanova, I., Ware, J., Tybulewicz, V. L. J. and Watson, S. P. (2007) GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk. Arteriosclerosis, thrombosis, and vascular biology, 27 (2). pp. 422-9. ISSN 1524-4636

Dhanjal, T. S., Ross, E. A., Auger, J. M., McCarty, O. J. T., Hughes, C. E., Senis, Y. A., Buckley, C. D. and Watson, S. P. (2007) Minimal regulation of platelet activity by PECAM-1. Platelets, 18 (1). pp. 56-67. ISSN 0953-7104

Suzuki-Inoue, K., Hughes, C. E., Inoue, O., Kaneko, M., Cuyun-Lira, O., Takafuta, T., Watson, S. P. and Ozaki, Y. (2007) Involvement of Src kinases and PLCgamma2 in clot retraction. Thrombosis research, 120 (2). pp. 251-8. ISSN 0049-3848

García, A., Senis, Y. A., Antrobus, R., Hughes, C. E., Dwek, R. A., Watson, S. P. and Zitzmann, N. (2006) A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter. Proteomics, 6 (19). pp. 5332-43. ISSN 1615-9853

Book or Report Section

Pollitt, A. Y., Hughes, C. E. and Watson, S. P. (2013) GPVI and CLEC-2. In: Michelson, A. D. (ed.) Platelets. 3rd edition. Academic Press, Amsterdam, pp. 215-231. ISBN 9780123878373 doi: https://doi.org/10.1016/B978-0-12-387837-3.00011-0

Conference or Workshop Item

Yu, T. Y., Finney, B. A., Hughes, C. E., Dehghani, H., Claridge, E. and Thomas, S. G. (2013) Three dimensional analysis of cardiovascular development in mouse embryos using X-ray microcomputed tomography. In: Microscopy and Analysis.

Thesis

Hughes, C. E. (2010) Comparison of CLEC-2 and GPVI signaling in platelets: the role of adaptor proteins. PhD thesis, University of Birmingham.

This list was generated on Sat Jul 21 10:38:41 2018 UTC.

Page navigation