Influence of the APOC3 −2854T>G polymorphism on plasma lipid levels: effect of age and gender
Minihane, A. M., Finnegan, Y., Talmud, P., Leigh-Firbank , E. and Williams, C. M. (2002) Influence of the APOC3 −2854T>G polymorphism on plasma lipid levels: effect of age and gender. Biochimica Et Biophysica Acta-Molecular and Cell Biology of Lipids, 1583 (3). pp. 311-314. ISSN 1388-1981
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To link to this article DOI: 10.1016/S1388-1981(02)00264-0
The APOC3 −2854T>G polymorphism lies in the APOC3–A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype–triglyceride interactions.