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Adipose tissue metabolism in pregnancy: the lipolytic effect of human placental lactogen

Coltart, T. M. and Williams, C. M. (1978) Adipose tissue metabolism in pregnancy: the lipolytic effect of human placental lactogen. British Journal of Obstetrics and Gynaecology, 85 (1). pp. 43-46. ISSN 0306-5456

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To link to this article DOI: 10.1111/j.1471-0528.1978.tb15824.x

Abstract/Summary

In vitro adipose tissue lipolysis was investigated in pregnant and non-pregnant women. Basal and hormone-stimulated rates of lipolysis were significantly higher in the pregnant group. Human placental lactogen (HPL) was shown to be lipolytic on adipose tissue from both pregnant and non-pregnant women; the response being more marked in the pregnant group. We postulate that HPL is responsible for this increased lipolytic sensitivity in pregnancy, the result of which is the elevation in levels of plasma free fatty acids in the third trimester.

Item Type:Article
Refereed:Yes
Divisions:Faculty of Life Sciences > School of Chemistry, Food and Pharmacy > Department of Food and Nutritional Sciences > Human Nutrition Research Group
Interdisciplinary centres and themes > Institute for Cardiovascular and Metabolic Research (ICMR)
ID Code:19518
Publisher:Wiley-Blackwell

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